Mismatch repair status in patients with primary operable colorectal cancer: Associations with the local and systemic tumour environment

British Journal of Cancer

Volumn 114, Issue 5, 2016, Pages 562-570

  Park, James H ^a   Powell, Arfon G ^b   Roxburgh, Campbell S D ^a   Horgan, Paul G ^a   McMillan, Donald C ^a   Edwards, Joanne ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

colorectal cancer; microsatellite instability; mismatch repair; systemic inflammation; tumour microenvironment

Indexed keywords

CD3 ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; MISMATCH REPAIR PROTEIN; ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; DNA LIGASE; G-T MISMATCH-BINDING PROTEIN; MISMATCH REPAIR PROTEIN PMS2; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; PROTEIN MSH2; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; AGED; ARTICLE; BLOOD CELL RATIO; CANCER CELL; CANCER PROGNOSIS; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CANCER SURGERY; CELL INFILTRATION; CLINICAL ASSESSMENT; COLORECTAL CANCER; COLORECTAL SURGERY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLASGOW PROGNOSTIC SCORE; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LEUKOCYTE DIFFERENTIAL COUNT; MAJOR CLINICAL STUDY; MALE; MISMATCH REPAIR; NEUTROPHIL COUNT; NEUTROPHIL LYMPHOCYTE RATIO; NEUTROPHIL PLATELET SCORE; PRIORITY JOURNAL; PROGNOSTIC ASSESSMENT; PROSPECTIVE STUDY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; T LYMPHOCYTE; TUMOR MICROENVIRONMENT; COHORT ANALYSIS; COLORECTAL TUMOR; FACTUAL DATABASE; GENETICS; IMMUNOLOGY; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; METABOLISM; MICROSATELLITE INSTABILITY; MIDDLE AGED; NEUTROPHIL; PROGNOSIS; TUMOR ASSOCIATED LEUKOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; AGED; COHORT STUDIES; COLORECTAL NEOPLASMS; DATABASES, FACTUAL; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MISMATCH REPAIR ENDONUCLEASE PMS2; MUTL PROTEIN HOMOLOG 1; MUTS HOMOLOG 2 PROTEIN; NEUTROPHILS; NUCLEAR PROTEINS; PROGNOSIS; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT;

EID: 84959333399     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2016.17     Document Type: Article

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