Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus

Critical Reviews in Microbiology

Volumn 42, Issue 2, 2016, Pages 310-321

  Lamoth, Frédéric ^a,b   Juvvadi, Praveen R ^a   Steinbach, William J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Antifungal resistance; Aspergillus fumigatus; calcineurin; geldanamycin; heat shock protein 90; invasive aspergillosis; lysine deacetylase; trichostatinA

Indexed keywords

ANTIFUNGAL AGENT; CALCINEURIN; CALCINEURIN INHIBITOR; CASPOFUNGIN; CHAPERONE; ECHINOCANDIN; EFUNGUMAB; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; LYSINE; NITRIC OXIDE; POLYENE; PYRROLE DERIVATIVE; VORICONAZOLE; CARRIER PROTEIN; PROTEIN BINDING;

ANTIFUNGAL ACTIVITY; ANTIFUNGAL RESISTANCE; ASPERGILLUS FUMIGATUS; CLINICAL FEATURE; DRUG TARGETING; ENZYME INHIBITION; FUNGUS GROWTH; GENE INTERACTION; GENE REPRESSION; HUMAN; INTRACELLULAR SIGNALING; INVASIVE ASPERGILLOSIS; NITROSYLATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEOMICS; REVIEW; STRESS; STRUCTURE ANALYSIS; SURVIVAL RATE; ANIMAL; ANTAGONISTS AND INHIBITORS; ASPERGILLOSIS; CHEMISTRY; DRUG EFFECTS; INTRACELLULAR SPACE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PHYSIOLOGICAL STRESS; PROTEIN TRANSPORT;

ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CARRIER PROTEINS; DRUG RESISTANCE, FUNGAL; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SPACE; MICROBIAL VIABILITY; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; STRESS, PHYSIOLOGICAL;

EID: 84959310693     PISSN: 1040841X     EISSN: 15497828     Source Type: Journal    
DOI: 10.3109/1040841X.2014.947239     Document Type: Review

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