Chronic cannabinoid exposure during adolescence leads to long-term structural and functional changes in the prefrontal cortex

European Neuropsychopharmacology

Volumn 26, Issue 1, 2016, Pages 55-64

  Renard, Justine ^a,b   Vitalis, Tania ^c,d   Rame, Marion ^a,b   Krebs, Marie Odile ^a,b   Lenkei, Zsolt ^c,d   Le Pen, Gwenaëlle ^a,b   Jay, Thérèse M ^a,b  

^a CENTRE DE PSYCHIATRIE ET NEUROSCIENCES   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c CNRS   (France)

^d PSL RESEARCH UNIVERSITY   (France)

Author keywords

Adolescence; Cannabinoid; Dendrites; Prefrontal structure; Synaptic markers; Synaptic plasticity

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; CANNABINOID; POSTSYNAPTIC DENSITY PROTEIN 95; 3-(2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL)-4-(3-HYDROXYPROPYL)CYCLOHEXANOL; CYCLOHEXANOL DERIVATIVE; DLGH4 PROTEIN, RAT; MEMBRANE PROTEIN; SIGNAL PEPTIDE; SYNAPTOPHYSIN; SYP PROTEIN, RAT; VESICULAR GLUTAMATE TRANSPORTER; VGLUT3 PROTEIN, RAT;

ADOLESCENCE; ADOLESCENT; ADULT; ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN MATURATION; CANNABIS USE; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITE; HIPPOCAMPUS; LONG TERM EXPOSURE; MALE; MEDIAL PREFRONTAL CORTEX; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; SYNAPSE; ANIMAL; CANNABIS ADDICTION; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; LONG TERM POTENTIATION; METABOLISM; MICROELECTRODE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING; WISTAR RAT;

ANIMALS; BLOTTING, WESTERN; CANNABINOIDS; CHRONIC DISEASE; CYCLOHEXANOLS; DENDRITES; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LONG-TERM POTENTIATION; MALE; MARIJUANA ABUSE; MEMBRANE PROTEINS; MICROELECTRODES; PREFRONTAL CORTEX; PYRAMIDAL CELLS; RATS, WISTAR; SYNAPTOPHYSIN; VESICULAR GLUTAMATE TRANSPORT PROTEINS;

EID: 84959179204     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2015.11.005     Document Type: Article

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