-
1
-
-
84904155440
-
Cancer treatment and survivorship statistics, 2014
-
DeSantis CE, Lin CC, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin. 2014;64:252-271.
-
(2014)
CA Cancer J Clin.
, vol.64
, pp. 252-271
-
-
DeSantis, C.E.1
Lin, C.C.2
Mariotto, A.B.3
-
2
-
-
76249089855
-
Annual report to the nation on the status of cancer 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates
-
Edwards BK, Ward E, Kohler BA, et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer. 2010;116:544-573.
-
(2010)
Cancer.
, vol.116
, pp. 544-573
-
-
Edwards, B.K.1
Ward, E.2
Kohler, B.A.3
-
3
-
-
77953744331
-
Cancer mortality in Europe, 2000-2004, and an overview of trends since 1975
-
La Vecchia C, Bosetti C, Lucchini F, et al. Cancer mortality in Europe, 2000-2004, and an overview of trends since 1975. Ann Oncol. 2010;21:1323-1360.
-
(2010)
Ann Oncol.
, vol.21
, pp. 1323-1360
-
-
La Vecchia, C.1
Bosetti, C.2
Lucchini, F.3
-
4
-
-
77957275712
-
Present status and perspectives of colorectal cancer in Asia: Colorectal Cancer Working Group report in 30th Asia-Pacific Cancer Conference
-
Hyodo I, Suzuki H, Takahashi K, et al. Present status and perspectives of colorectal cancer in Asia: Colorectal Cancer Working Group report in 30th Asia-Pacific Cancer Conference. Jpn J Clin Oncol. 2010;40(Suppl. 1):i38-i43.
-
(2010)
Jpn J Clin Oncol.
, vol.40
, pp. i38-i43
-
-
Hyodo, I.1
Suzuki, H.2
Takahashi, K.3
-
5
-
-
84960804853
-
The role of virtual colonoscopy in colorectal screening
-
PMID: 26298421
-
Patel JD, Chang KJ. The role of virtual colonoscopy in colorectal screening. Clin Imaging. 2015. PMID: 26298421.
-
(2015)
Clin Imaging.
-
-
Patel, J.D.1
Chang, K.J.2
-
6
-
-
84891800145
-
Metformin and the incidence of cancer in patients with diabetes: A nested case-control study
-
Wang SY, Chuang CS, Muo CH, et al. Metformin and the incidence of cancer in patients with diabetes: a nested case-control study. Diabetes Care. 2013;36:e155-e156.
-
(2013)
Diabetes Care.
, vol.36
, pp. e155-e156
-
-
Wang, S.Y.1
Chuang, C.S.2
Muo, C.H.3
-
7
-
-
78649302320
-
Metformin and cancer risk in diabetic patients: A systematic review and meta-analysis
-
Decensi A, Puntoni M, Goodwin P, et al. Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis. Cancer Prev Res (Phila). 2010;3:1451-1461.
-
(2010)
Cancer Prev Res (Phila).
, vol.3
, pp. 1451-1461
-
-
Decensi, A.1
Puntoni, M.2
Goodwin, P.3
-
8
-
-
45849134512
-
Why diabetes patients are more prone to the development of colon cancer?
-
Jin T. Why diabetes patients are more prone to the development of colon cancer? Med Hypotheses. 2008;71:241-244.
-
(2008)
Med Hypotheses.
, vol.71
, pp. 241-244
-
-
Jin, T.1
-
10
-
-
0037313036
-
Impact of diabetes mellitus on outcomes in patients with colon cancer
-
Meyerhardt JA, Catalano PJ, Haller DG, et al. Impact of diabetes mellitus on outcomes in patients with colon cancer. J Clin Oncol. 2003;21:433-440.
-
(2003)
J Clin Oncol.
, vol.21
, pp. 433-440
-
-
Meyerhardt, J.A.1
Catalano, P.J.2
Haller, D.G.3
-
12
-
-
84859076050
-
Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: Results from a large population-based follow-up study
-
Ruiter R, Visser LE, van Herk-Sukel MP, et al. Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: results from a large population-based follow-up study. Diabetes Care. 2012;35:119-124.
-
(2012)
Diabetes Care.
, vol.35
, pp. 119-124
-
-
Ruiter, R.1
Visser, L.E.2
Van Herk-Sukel, M.P.3
-
13
-
-
84925356673
-
Metformin for primary colorectal cancer prevention in patients with diabetes: A case-control study in a US population
-
Sehdev A, Shih YC, Vekhter B, et al. Metformin for primary colorectal cancer prevention in patients with diabetes: a case-control study in a US population. Cancer. 2015;121:1071-1078.
-
(2015)
Cancer.
, vol.121
, pp. 1071-1078
-
-
Sehdev, A.1
Shih, Y.C.2
Vekhter, B.3
-
14
-
-
84891540896
-
Use of biguanides and the risk of colorectal cancer: A register-based cohort study
-
Knapen LM, Dittrich ST, de Vries F, et al. Use of biguanides and the risk of colorectal cancer: a register-based cohort study. Curr Drug Saf. 2013;8:349-356.
-
(2013)
Curr Drug Saf.
, vol.8
, pp. 349-356
-
-
Knapen, L.M.1
Dittrich, S.T.2
De Vries, F.3
-
15
-
-
84857073798
-
Use of metformin is not associated with a decreased risk of colorectal cancer: A case-control analysis
-
Bodmer M, Becker C, Meier C, et al. Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis. Cancer Epidemiol Biomarkers Prev. 2012;21:280-286.
-
(2012)
Cancer Epidemiol Biomarkers Prev.
, vol.21
, pp. 280-286
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
-
16
-
-
84938983934
-
No reduced risk of overall, colorectal, lung, breast, and prostate cancer with metformin therapy in diabetic patients: Database analyses from Germany and the UK
-
Kowall B, Stang A, Rathmann W, et al. No reduced risk of overall, colorectal, lung, breast, and prostate cancer with metformin therapy in diabetic patients: database analyses from Germany and the UK. Pharmacoepidemiol Drug Saf. 2015.
-
(2015)
Pharmacoepidemiol Drug Saf.
-
-
Kowall, B.1
Stang, A.2
Rathmann, W.3
-
17
-
-
77953589054
-
Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase
-
Algire C, Amrein L, Zakikhani M, et al. Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase. Endocr Relat Cancer. 2010;17:351-360.
-
(2010)
Endocr Relat Cancer.
, vol.17
, pp. 351-360
-
-
Algire, C.1
Amrein, L.2
Zakikhani, M.3
-
18
-
-
55449124298
-
Metformin suppresses intestinal polyp growth in ApcMin/mice
-
Tomimoto A, Endo H, Sugiyama M, et al. Metformin suppresses intestinal polyp growth in ApcMin/mice. Cancer Sci. 2008;99:2136-2141.
-
(2008)
Cancer Sci.
, vol.99
, pp. 2136-2141
-
-
Tomimoto, A.1
Endo, H.2
Sugiyama, M.3
-
19
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001;108:1167-1174.
-
(2001)
J Clin Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
-
20
-
-
80053992117
-
Metformin as an antitumor agent in cancer prevention and treatment
-
Li D. Metformin as an antitumor agent in cancer prevention and treatment. J Diabetes. 2011;3:320-327.
-
(2011)
J Diabetes.
, vol.3
, pp. 320-327
-
-
Li, D.1
-
21
-
-
84928753669
-
Preferred reporting items for a systematic review and meta-analysis of individual participant data the PRISMA-IPD Statement
-
Stewart LA, Clarke M, Rovers M, et al. Preferred reporting items for a systematic review and meta-analysis of individual participant data The PRISMA-IPD Statement. JAMA. 2015;313:1657-1665.
-
(2015)
JAMA
, vol.313
, pp. 1657-1665
-
-
Stewart, L.A.1
Clarke, M.2
Rovers, M.3
-
24
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-1558.
-
(2002)
Stat Med.
, vol.21
, pp. 1539-1558
-
-
Higgins, J.P.1
Thompson, S.G.2
-
25
-
-
0028152471
-
Why sources of heterogeneity in meta-analysis should be investigated
-
Thompson SG. Why sources of heterogeneity in meta-analysis should be investigated. BMJ. 1994;309:1351-1355.
-
(1994)
BMJ
, vol.309
, pp. 1351-1355
-
-
Thompson, S.G.1
-
26
-
-
84865717087
-
Diabetes metformin use, and colon cancer: A population-based cohort study in Taiwan
-
Tseng CH. Diabetes, metformin use, and colon cancer: a population-based cohort study in Taiwan. Eur J Endocrinol. 2012;167:409-416.
-
(2012)
Eur J Endocrinol.
, vol.167
, pp. 409-416
-
-
Tseng, C.H.1
-
27
-
-
84929339047
-
Association between gastro-enterological malignancy and diabetes mellitus and anti-diabetic therapy: A nationwide, population-based cohort study
-
Lin CM, Huang HL, Chu FY, et al. Association between gastro-enterological malignancy and diabetes mellitus and anti-diabetic therapy: a nationwide, population-based cohort study. PLoS ONE. 2015;10:e0125421.
-
(2015)
PLoS ONE.
, vol.10
, pp. e0125421
-
-
Lin, C.M.1
Huang, H.L.2
Chu, F.Y.3
-
28
-
-
78651451726
-
Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: A representative population prospective cohort study of 800, 000 individuals
-
Lee MS, Hsu CC, Wahlqvist ML, et al. Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800, 000 individuals. BMC Cancer. 2011;11:20.
-
(2011)
BMC Cancer.
, vol.11
, pp. 20
-
-
Lee, M.S.1
Hsu, C.C.2
Wahlqvist, M.L.3
-
29
-
-
5144234027
-
Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients
-
Yang YX, Hennessy S, Lewis JD. Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients. Gastroenterol-ogy. 2004;127:1044-1050.
-
(2004)
Gastroenterol-ogy.
, vol.127
, pp. 1044-1050
-
-
Yang, Y.X.1
Hennessy, S.2
Lewis, J.D.3
-
30
-
-
84886416382
-
The use of metformin and colorectal cancer incidence in patients with type II diabetes mellitus
-
Smiechowski B, Azoulay L, Yin H, et al. The use of metformin and colorectal cancer incidence in patients with type II diabetes mellitus. Cancer Epidemiol Biomarkers Prev. 2013;22:1877-1883.
-
(2013)
Cancer Epidemiol Biomarkers Prev.
, vol.22
, pp. 1877-1883
-
-
Smiechowski, B.1
Azoulay, L.2
Yin, H.3
-
31
-
-
84874322688
-
Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus
-
Qiu H, Rhoads GG, Berlin JA, et al. Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus. Diabetes Obes Metab. 2013;15:349-357.
-
(2013)
Diabetes Obes Metab.
, vol.15
, pp. 349-357
-
-
Qiu, H.1
Rhoads, G.G.2
Berlin, J.A.3
-
32
-
-
84928658794
-
Validating drug repurposing signals using electronic health records: A case study of metformin associated with reduced cancer mortality
-
Xu H, Aldrich MC, Chen Q, et al. Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality. J Am Med Inform Assoc. 2015;22:179-191.
-
(2015)
J Am Med Inform Assoc.
, vol.22
, pp. 179-191
-
-
Xu, H.1
Aldrich, M.C.2
Chen, Q.3
-
33
-
-
79956226830
-
Cohort study of pioglitazone and cancer incidence in patients with diabetes
-
Ferrara A, Lewis JD, Quesenberry CP Jr et al. Cohort study of pioglitazone and cancer incidence in patients with diabetes. Diabetes Care. 2011;34:923-929.
-
(2011)
Diabetes Care.
, vol.34
, pp. 923-929
-
-
Ferrara, A.1
Lewis, J.D.2
Quesenberry, C.P.3
-
34
-
-
84882273707
-
A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer
-
Spillane S, Bennett K, Sharp L, et al. A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2013;22:1364-1373.
-
(2013)
Cancer Epidemiol Biomarkers Prev.
, vol.22
, pp. 1364-1373
-
-
Spillane, S.1
Bennett, K.2
Sharp, L.3
-
35
-
-
84861576077
-
The effects of metformin on the survival of colorectal cancer patients with diabetes mellitus
-
Lee JH, Kim TI, Jeon SM, et al. The effects of metformin on the survival of colorectal cancer patients with diabetes mellitus. Int J Cancer. 2012;131:752-759.
-
(2012)
Int J Cancer.
, vol.131
, pp. 752-759
-
-
Lee, J.H.1
Kim, T.I.2
Jeon, S.M.3
-
36
-
-
84884130619
-
Diabetes, metformin use, and colorectal cancer survival in postmenopausal women
-
Cossor FI, Adams-Campbell LL, Chlebowski RT, et al. Diabetes, metformin use, and colorectal cancer survival in postmenopausal women. Cancer Epidemiol. 2013;37:742-749.
-
(2013)
Cancer Epidemiol.
, vol.37
, pp. 742-749
-
-
Cossor, F.I.1
Adams-Campbell, L.L.2
Chlebowski, R.T.3
-
37
-
-
77955558076
-
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglita-zone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials
-
Home PD, et al. Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglita-zone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials. Diabetologia. 2010;53:1838-1845.
-
(2010)
Diabetologia.
, vol.53
, pp. 1838-1845
-
-
Home, P.D.1
-
38
-
-
84991494403
-
Long-term use of metformin and colorectal cancer risk in type II diabetics: A population-based case-control study
-
Cardel M, Jensen SM, Pottegard A, et al. Long-term use of metformin and colorectal cancer risk in type II diabetics: a population-based case-control study. Cancer Med. 2014;3: 1458-1466.
-
(2014)
Cancer Med.
, vol.3
, pp. 1458-1466
-
-
Cardel, M.1
Jensen, S.M.2
Pottegard, A.3
-
40
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie CJ, Poole CD, Gale EA. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia. 2009;52:1766-1777.
-
(2009)
Diabetologia.
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
41
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby G, et al. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care. 2009;32:1620-1625.
-
(2009)
Diabetes Care.
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
-
42
-
-
84856701110
-
Further exploration of the relationship between insulin glargine and incident cancer: A retrospective cohort study of older Medicare patients
-
Morden NE, et al. Further exploration of the relationship between insulin glargine and incident cancer: a retrospective cohort study of older Medicare patients. Diabetes Care. 2011;34:1965-1971.
-
(2011)
Diabetes Care.
, vol.34
, pp. 1965-1971
-
-
Morden, N.E.1
-
43
-
-
84906691535
-
Metformin does not affect cancer risk: A cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial
-
Tsillidis KK, et al. Metformin does not affect cancer risk: a cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial. Diabetes Care. 2014;37:2522-2532.
-
(2014)
Diabetes Care.
, vol.37
, pp. 2522-2532
-
-
Tsillidis, K.K.1
-
44
-
-
84859631091
-
Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer
-
Garrett CR, et al. Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer. Br J Cancer. 2012;106:1374-1378.
-
(2012)
Br J Cancer.
, vol.106
, pp. 1374-1378
-
-
Garrett, C.R.1
-
45
-
-
84859029647
-
Mortality after incident cancer in people with and without type 2 diabetes: Impact of metformin on survival
-
Currie CJ, et al. Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival. Diabetes Care. 2012;35:299-304.
-
(2012)
Diabetes Care.
, vol.35
, pp. 299-304
-
-
Currie, C.J.1
-
46
-
-
79961238388
-
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
-
Sterne JA, Sutton AJ, Ioannidis JP, et al. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ. 2011;343:d4002.
-
(2011)
BMJ.
, vol.343
, pp. d4002
-
-
Sterne, J.A.1
Sutton, A.J.2
Ioannidis, J.P.3
-
47
-
-
84890036692
-
Antidiabetic medications and the risk of colorectal cancer in patients with diabetes mellitus: A systematic review and meta-analysis
-
Singh S, Singh H, Singh PP, et al. Antidiabetic medications and the risk of colorectal cancer in patients with diabetes mellitus: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2013;22:2258-2268.
-
(2013)
Cancer Epidemiol Biomarkers Prev.
, vol.22
, pp. 2258-2268
-
-
Singh, S.1
Singh, H.2
Singh, P.P.3
-
48
-
-
84858693012
-
Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: A meta-analysis
-
Zhang ZJ, Zheng ZJ, Kan H, et al. Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis. Diabetes Care. 2011;34:2323-2328.
-
(2011)
Diabetes Care.
, vol.34
, pp. 2323-2328
-
-
Zhang, Z.J.1
Zheng, Z.J.2
Kan, H.3
-
49
-
-
84869788946
-
Metformin and the risk of cancer: Time-related biases in observational studies
-
Suissa S, Azoulay L. Metformin and the risk of cancer: time-related biases in observational studies. Diabetes Care. 2012;35:2665-2673.
-
(2012)
Diabetes Care.
, vol.35
, pp. 2665-2673
-
-
Suissa, S.1
Azoulay, L.2
-
50
-
-
84907296915
-
Metformin and cancer risk and mortality: A systematic review and meta-analysis taking into account biases and confounders
-
Gandini S, Puntoni M, Heckman-Stoddard BM, et al. Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders. Cancer Prev Res (Phila). 2014;7:867-885.
-
(2014)
Cancer Prev Res (Phila).
, vol.7
, pp. 867-885
-
-
Gandini, S.1
Puntoni, M.2
Heckman-Stoddard, B.M.3
-
51
-
-
84857975015
-
Metformin: Multi-faceted protection against cancer
-
Del Barco S, Vazquez-Martin A, Cufi S, et al. Metformin: multi-faceted protection against cancer. Oncotarget. 2011;2:896-917.
-
(2011)
Oncotarget.
, vol.2
, pp. 896-917
-
-
Del Barco, S.1
Vazquez-Martin, A.2
Cufi, S.3
-
52
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, et al. Glycolytic enzymes can modulate cellular life span. Cancer Res. 2005;65:177-185.
-
(2005)
Cancer Res.
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
-
54
-
-
78649858143
-
AMPK as a therapeutic target in renal cell carcinoma
-
Woodard J, Joshi S, Viollet B, et al. AMPK as a therapeutic target in renal cell carcinoma. Cancer Biol Ther. 2010;10:1168-1177.
-
(2010)
Cancer Biol Ther.
, vol.10
, pp. 1168-1177
-
-
Woodard, J.1
Joshi, S.2
Viollet, B.3
-
55
-
-
44849099894
-
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
-
Ben Sahra I, Laurent K, Loubat A, et al. The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene. 2008;27:3576-3586.
-
(2008)
Oncogene.
, vol.27
, pp. 3576-3586
-
-
Ben Sahra, I.1
Laurent, K.2
Loubat, A.3
-
56
-
-
77954468475
-
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase
-
Hosono K, Endo H, Takahashi H, et al. Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase. Mol Carcinog. 2010;49:662-671.
-
(2010)
Mol Carcinog.
, vol.49
, pp. 662-671
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
|