The macromolecular architecture of platelet-derived microparticles

Journal of Structural Biology

Volumn 193, Issue 3, 2016, Pages 181-187

  Tamir, Adi ^a   Sorrentino, Simona ^b   Motahedeh, Sarah ^c   Shai, Ela ^c   Dubrovsky, Anna ^b   Dahan, Idit ^a   Eibauer, Matthias ^b   Studt, Jan Dirk ^d   Sapra, K Tanuj ^b   Varon, David ^c   Medalia, Ohad ^a,b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Cryo electron tomography

Indexed keywords

FIBRINOGEN; INTEGRIN RECEPTOR; MANGANESE; THROMBIN; FIBRINOGEN RECEPTOR;

ARTICLE; CELL ISOLATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CYTOSKELETON; ELECTRON TOMOGRAPHY; GLANZMANN DISEASE; HUMAN; HUMAN CELL; PLATELET MICROPARTICLE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; BLOOD; CELL ADHESION; CHEMISTRY; GENETICS; MEMBRANE MICROPARTICLE; METABOLISM; PATHOLOGY; THROMBOCYTE; ULTRASTRUCTURE;

BLOOD PLATELETS; CELL ADHESION; CELL-DERIVED MICROPARTICLES; CRYOELECTRON MICROSCOPY; CYTOSKELETON; FIBRINOGEN; HUMANS; MANGANESE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBASTHENIA; THROMBIN;

EID: 84959151786     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2015.12.013     Document Type: Article

References (54)

1. Amiry-Moghaddam M., Ottersen O.P. Immunogold cytochemistry in neuroscience. Nat. Neurosci. 2013, 16:798-804.
2. Capriotti A.L., Caruso G., Cavaliere C., Piovesana S., Samperi R., Lagana A. Proteomic characterization of human platelet-derived microparticles. Anal. Chim. Acta 2013, 776:57-63.
3. Cauwenberghs S., Feijge M.A., Harper A.G., Sage S.O., Curvers J., Heemskerk J.W. Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton. FEBS Lett. 2006, 580:5313-5320.
4. Choi W.S., Rice W.J., Stokes D.L., Coller B.S. Three-dimensional reconstruction of intact human integrin alphaIIbbeta3: new implications for activation-dependent ligand binding. Blood 2013, 122:4165-4171.
5. Dai A., Ye F., Taylor D.W., Hu G., Ginsberg M.H., Taylor K.A. The structure of a full-length membrane-embedded integrin bound to a physiological ligand. J. Biol. Chem. 2015.
6. Diamant M., Tushuizen M.E., Sturk A., Nieuwland R. Cellular microparticles: new players in the field of vascular disease?. Eur. J. Clin. Invest. 2004, 34:392-401.
7. Dubochet J., Adrian M., Chang J.J., Homo J.C., Lepault J., McDowall A.W., Schultz P. Cryo-electron microscopy of vitrified specimens. Q. Rev. Biophys. 1988, 21:129-228.
8. Gailit J., Ruoslahti E. Regulation of the fibronectin receptor affinity by divalent cations. J. Biol. Chem. 1988, 263:12927-12932.
9. Galkin V.E., Orlova A., Vos M.R., Schroder G.F., Egelman E.H. Near-atomic resolution for one state of F-actin. Structure 2015, 23:173-182.
10. Garcia B.A., Smalley D.M., Cho H., Shabanowitz J., Ley K., Hunt D.F. The platelet microparticle proteome. J. Proteome Res. 2005, 4:1516-1521.
11. George J.N., Caen J.P., Nurden A.T. Glanzmann's thrombasthenia: the spectrum of clinical disease. Blood 1990, 75:1383-1395.
12. Ginsberg M.H. Integrins - dynamic regulation of ligand-binding. Biochem. Soc. Trans. 1995, 23:439-446.
13. Goodnight S.H., Coull B.M., McAnulty J.H., Taylor L.M. Antiplatelet therapy-Part II. West. J. Med. 1993, 158:506-514.
14. Gore I., Takada M., Austin J. Ultrastructural basis of experimental thrombocytopenic purpura. Arch. Pathol. 1970, 90:197-205.
15. Harapin J., Eibauer M., Medalia O. Structural analysis of supramolecular assemblies by cryo-electron tomography. Structure 2013, 21:1522-1530.
16. Hartwig J.H. Mechanisms of actin rearrangements mediating platelet activation. J. Cell Biol. 1992, 118:1421-1442.
17. Herring J.M., McMichael M.A., Smith S.A. Microparticles in health and disease. J. Vet. Intern. Med. 2013, 27:1020-1033.
18. Hess J.R. Conventional blood banking and blood component storage regulation: opportunities for improvement. Blood Transfus. 2010, 8(Suppl. 3):s9-s15.
19. Kahn M.L., Zheng Y.W., Huang W., Bigornia V., Zeng D., Moff S., Farese R.V., Tam C., Coughlin S.R. A dual thrombin receptor system for platelet activation. Nature 1998, 394:690-694.
20. Kahner B.N., Kato H., Banno A., Ginsberg M.H., Shattil S.J., Ye F. Kindlins, integrin activation and the regulation of talin recruitment to alphaIIbbeta3. PLoS ONE 2012, 7:e34056.
21. Kanchanawong P., Shtengel G., Pasapera A.M., Ramko E.B., Davidson M.W., Hess H.F., Waterman C.M. Nanoscale architecture of integrin-based cell adhesions. Nature 2010, 468:580-584.
22. Kim M., Carman C.V., Springer T.A. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 2003, 301:1720-1725.
23. Matzdorff A., Kemkes-Matthes B., Pralle H. Microparticles and reticulated platelets in Wiskott-Aldrich syndrome patients. Br. J. Haematol. 2000, 109:673.
24. Medalia O., Weber I., Frangakis A.S., Nicastro D., Gerisch G., Baumeister W. Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography. Science 2002, 298:1209-1213.
25. Medalia O., Beck M., Ecke M., Weber I., Neujahr R., Baumeister W., Gerisch G. Organization of actin networks in intact filopodia. Curr. Biol. 2007, 17:79-84.
26. Milioli M., Ibanez-Vea M., Sidoli S., Palmisano G., Careri M., Larsen M.R. Quantitative proteomics analysis of platelet-derived microparticles reveals distinct protein signatures when stimulated by different physiological agonists. J. Proteomics 2015, 121:56-66.
27. Nachmias V.T., Sullender J., Fallon J., Asch A. Observations on the "cytoskeleton" of human platelets. Thromb. Haemost. 1980, 42:1661-1666.
28. Nickell S., Forster F., Linaroudis A., Net W.D., Beck F., Hegerl R., Baumeister W., Plitzko J.M. TOM software toolbox: acquisition and analysis for electron tomography. J. Struct. Biol. 2005, 149:227-234.
29. Patla I., Volberg T., Elad N., Hirschfeld-Warneken V., Grashoff C., Fassler R., Spatz J.P., Geiger B., Medalia O. Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. Nat. Cell Biol. 2010, 12:909-915.
30. Posch S., Neundlinger I., Leitner M., Siostrzonek P., Panzer S., Hinterdorfer P., Ebner A. Activation induced morphological changes and integrin alphaIIbbeta3 activity of living platelets. Methods 2013, 60:179-185.
31. Ross R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 1999, 340:115-126.
32. Sakariassen K.S., Holme P.A., Orvim U., Barstad R.M., Solum N.O., Brosstad F.R. Shear-induced platelet activation and platelet microparticle formation in native human blood. Thromb. Res. 1998, 92:S33-S41.
33. Saumet A., de Jesus N., Legrand C., Dubernard V. Association of thrombospondin-1 with the actin cytoskeleton of human thrombin-activated platelets through an alphaIIbbeta3- or CD36-independent mechanism. Biochem. J. 2002, 363:473-482.
34. Seligsohn U. Glanzmann thrombasthenia: a model disease which paved the way to powerful therapeutic agents. Pathophysiol. Haemost. Thromb. 2002, 32:216-217.
35. Shah M.D., Bergeron A.L., Dong J.F., Lopez J.A. Flow cytometric measurement of microparticles: pitfalls and protocol modifications. Platelets 2008, 19:365-372.
36. Shai E., Rosa I., Parguina A.F., Motahedeh S., Varon D., Garcia A. Comparative analysis of platelet-derived microparticles reveals differences in their amount and proteome depending on the platelet stimulus. J. Proteomics 2012, 76:287-296.
37. Shattil S.J., Newman P.J. Integrins: dynamic scaffolds for adhesion and signaling in platelets. Blood 2004, 104:1606-1615.
38. Shattil S.J., Kim C., Ginsberg M.H. The final steps of integrin activation: the end game. Nat. Rev. Mol. Cell Biol. 2010, 11:288-300.
39. Sorrentino S., Studt J.D., Medalia O., Tanuj Sapra K. Roll, adhere, spread and contract: structural mechanics of platelet function. Eur. J. Cell Biol. 2015, 94:129-138.
40. Takagi J., Petre B.M., Walz T., Springer T.A. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 2002, 110. 599-511.
41. Tanaka K., Itoh K. Reorganization of stress fiber-like structures in spreading platelets during surface activation. J. Struct. Biol. 1998, 124:13-41.
42. Tee Y.H., Shemesh T., Thiagarajan V., Hariadi R.F., Anderson K.L., Page C., Volkmann N., Hanein D., Sivaramakrishnan S., Kozlov M.M., Bershadsky A.D. Cellular chirality arising from the self-organization of the actin cytoskeleton. Nat. Cell Biol. 2015, 17:445-457.
43. Tiwari A., Jung J.J., Inamdar S.M., Brown C.O., Goel A., Choudhury A. Endothelial cell migration on fibronectin is regulated by syntaxin 6-mediated alpha5beta1 integrin recycling. J. Biol. Chem. 2011, 286:36749-36761.
44. Tseng C.C., Wang C.C., Chang H.C., Tsai T.H., Chang L.T., Huang K.T., Leu S., Yen C.H., Liu S.F., Chen C.H., Yang C.T., Yip H.K., Lin M.C. Levels of circulating microparticles in lung cancer patients and possible prognostic value. Dis. Markers 2013, 35:301-310.
45. Versteeg H.H., Heemskerk J.W., Levi M., Reitsma P.H. New fundamentals in hemostasis. Physiol. Rev. 2013, 93:327-358.
46. Vu T.K., Hung D.T., Wheaton V.I., Coughlin S.R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991, 64:1057-1068.
47. Wagner C.L., Mascelli M.A., Neblock D.S., Weisman H.F., Coller B.S., Jordan R.E. Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets. Blood 1996, 88:907-914.
48. Wang R., Stone R.L., Kaelber J.T., Rochat R.H., Nick A.M., Vijayan K.V., Afshar-Kharghan V., Schmid M.F., Dong J.F., Sood A.K., Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proc. Natl. Acad. Sci. U.S.A. 2015, 112:14266-14271.
49. Xiao T., Takagi J., Coller B.S., Wang J.H., Springer T.A. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature 2004, 432:59-67.
50. Yahav T., Maimon T., Grossman E., Dahan I., Medalia O. Cryo-electron tomography: gaining insight into cellular processes by structural approaches. Curr. Opin. Struct. Biol. 2011, 21:670-677.
51. Ye F., Kim C., Ginsberg M.H. Reconstruction of integrin activation. Blood 2012, 119:26-33.
52. 2+ activation when observed by cryoelectron tomography. J. Mol. Biol. 2008, 378:976-986.
53. Ye F., Hu G., Taylor D., Ratnikov B., Bobkov A.A., McLean M.A., Sligar S.G., Taylor K.A., Ginsberg M.H. Recreation of the terminal events in physiological integrin activation. J. Cell Biol. 2010, 188:157-173.
54. Yuana Y., Oosterkamp T.H., Bahatyrova S., Ashcroft B., Garcia Rodriguez P., Bertina R.M., Osanto S. Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles. J. Thromb. Haemost. 2010, 8:315-323.