The structure of a full-length membrane-embedded Integrin bound to a physiological Ligand

Journal of Biological Chemistry

Volumn 290, Issue 45, 2015, Pages 27168-27175

  Dai, Aguang ^a   Ye, Feng ^c   Taylor, Dianne W ^a   Hu, Guiqing ^a   Ginsberg, Mark H ^b   Taylor, Kenneth A ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Allele Biotechnology and Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEINS; MANGANESE; PHYSIOLOGY;

CONFORMATIONAL CHANGE; INTEGRINS; MACROMOLECULAR LIGANDS; NANODISCS; PHYSIOLOGICAL LIGANDS; PHYSIOLOGICAL SUBSTRATE;

LIGANDS;

ALPHAIIB BETA3 INTEGRIN; BETA3 INTEGRIN; FIBRIN; INTEGRIN; MANGANESE; MANGANESE CHLORIDE; NANODISC; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR; LIGAND; MEMBRANE LIPID; NANOMATERIAL; PROTEIN BINDING;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBEDDING; LIGAND BINDING; MEMBRANE BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; CHEMISTRY; HUMAN; IN VITRO STUDY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; THROMBOCYTE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

BLOOD PLATELETS; FIBRIN; HUMANS; IN VITRO TECHNIQUES; LIGANDS; MANGANESE; MEMBRANE LIPIDS; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; NANOSTRUCTURES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84946599583     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.682377     Document Type: Article

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