Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Feng, Bo ^a   Tang, Yangshun ^a   Chen, Bin ^a   Xu, Cenglin ^a   Wang, Yi ^a   Dai, Yunjian ^a   Wu, Dengchang ^a,b   Zhu, Junmin ^b   Wang, Shuang ^b   Zhou, Yudong ^a   Shi, Liyun ^c   Hu, Weiwei ^a   Zhang, Xia ^d   Chen, Zhong ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c HANGZHOU NORMAL UNIVERSITY   (China)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,6-BIS(CYCLOHEXYLOXIMINOCARBONYL)HEXANE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; BENZOXAZINE DERIVATIVE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CYCLOHEXANONE DERIVATIVE; IL1B PROTEIN, MOUSE; IL1RN PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIPOPROTEIN LIPASE; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; RIMONABANT; SMALL INTERFERING RNA;

AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; FEBRILE CONVULSION; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; SEIZURE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TISSUE CULTURE TECHNIQUE;

AGING; ANIMALS; BENZOXAZINES; CANNABINOID RECEPTOR ANTAGONISTS; CYCLOHEXANONES; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LIPOPROTEIN LIPASE; MICE; MICE, KNOCKOUT; MORPHOLINES; NAPHTHALENES; PIPERIDINES; PYRAZOLES; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RNA, SMALL INTERFERING; SEIZURES; SEIZURES, FEBRILE; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES;

EID: 84959140190     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21931     Document Type: Article

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