IL-1 receptor blockade prevents fetal cortical brain injury but not preterm birth in a mouse model of inflammation-induced preterm birth and perinatal brain injury

American Journal of Reproductive Immunology

Volumn 71, Issue 5, 2014, Pages 418-426

  Leitner, Kirstin ^a   Al Shammary, Mofeedah ^b   Mclane, Michael ^a   Johnston, Michael V ^b,c   Elovitz, Michal A ^a   Burd, Irina ^b,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

IL 1 receptor antagonist; Intrauterine inflammation; Mouse model

Indexed keywords

INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NEURONAL NITRIC OXIDE SYNTHASE; NOS1 PROTEIN, HUMAN;

ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; BRAIN INJURIES; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; FEMALE; FETUS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; METABOLISM; MOUSE; NEWBORN; PATHOLOGY; PREGNANCY; PREMATURITY; SIGNAL TRANSDUCTION; UTERUS;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; FETUS; GENE EXPRESSION REGULATION; HUMANS; INFANT, NEWBORN; INFLAMMATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; NITRIC OXIDE SYNTHASE TYPE I; PREGNANCY; PREMATURE BIRTH; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; UTERUS;

EID: 84898809350     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/aji.12216     Document Type: Article

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