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Volumn 2016, Issue , 2016, Pages

Manufacturing of Human Umbilical Cord Mesenchymal Stromal Cells on Microcarriers in a Dynamic System for Clinical Use

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOREACTOR; CELL EXPANSION; CELL GROWTH; CELL ISOLATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INOCULATION; MALE; MESENCHYMAL STROMA CELL; MICROCARRIER CULTURE; PRIORITY JOURNAL; QUALITY CONTROL; UMBILICAL CORD;

EID: 84959108411     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2016/4834616     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 84862746616 scopus 로고    scopus 로고
    • Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics
    • C. L. Elseberg, J. Leber, D. Salzig et al., "Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics," International Journal of Artificial Organs, vol. 35, no. 2, pp. 93-107, 2012.
    • (2012) International Journal of Artificial Organs , vol.35 , Issue.2 , pp. 93-107
    • Elseberg, C.L.1    Leber, J.2    Salzig, D.3
  • 2
    • 68749109438 scopus 로고    scopus 로고
    • Growth, metabolism, and growth inhibitors of mesenchymal stem cells
    • D. Schop, F. W. Janssen, L. D. S. van Rijn et al., "Growth, metabolism, and growth inhibitors of mesenchymal stem cells," Tissue Engineering. Part A, vol. 15, no. 8, pp. 1877-1886, 2009.
    • (2009) Tissue Engineering. Part A , vol.15 , Issue.8 , pp. 1877-1886
    • Schop, D.1    Janssen, F.W.2    Van Rijn, L.D.S.3
  • 3
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for non-hematopoietic tissues
    • D. J. Prockop, "Marrow stromal cells as stem cells for non-hematopoietic tissues," Science, vol. 276, no. 5309, pp. 71-74, 1997.
    • (1997) Science , vol.276 , Issue.5309 , pp. 71-74
    • Prockop, D.J.1
  • 4
    • 0034975453 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Building blocks for molecular medicine in the 21st century
    • A. I. Caplan and S. P. Bruder, "Mesenchymal stem cells: building blocks for molecular medicine in the 21st century," Trends in Molecular Medicine, vol. 7, no. 6, pp. 259-264, 2001.
    • (2001) Trends in Molecular Medicine , vol.7 , Issue.6 , pp. 259-264
    • Caplan, A.I.1    Bruder, S.P.2
  • 5
    • 27544441193 scopus 로고    scopus 로고
    • Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood
    • W. Wagner, F. Wein, A. Seckinger et al., "Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood," Experimental Hematology, vol. 33, no. 11, pp. 1402-1416, 2005.
    • (2005) Experimental Hematology , vol.33 , Issue.11 , pp. 1402-1416
    • Wagner, W.1    Wein, F.2    Seckinger, A.3
  • 6
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • M. F. Pittenger, A. M. Mackay, S. C. Beck et al., "Multilineage potential of adult human mesenchymal stem cells," Science, vol. 284, no. 5411, pp. 143-147, 1999.
    • (1999) Science , vol.284 , Issue.5411 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 7
    • 3242755834 scopus 로고    scopus 로고
    • A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential
    • G. Kögler, S. Sensken, J. A. Airey et al., "A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential," Journal of Experimental Medicine, vol. 200, no. 2, pp. 123-135, 2004.
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.2 , pp. 123-135
    • Kögler, G.1    Sensken, S.2    Airey, J.A.3
  • 8
    • 33846406448 scopus 로고    scopus 로고
    • Stem cells in the umbilical cord
    • M. L. Weiss and D. L. Troyer, "Stem cells in the umbilical cord," Stem Cell Reviews, vol. 2, no. 2, pp. 155-162, 2006.
    • (2006) Stem Cell Reviews , vol.2 , Issue.2 , pp. 155-162
    • Weiss, M.L.1    Troyer, D.L.2
  • 9
    • 84930196394 scopus 로고    scopus 로고
    • Wharton's Jelly-derived mesenchymal stromal cells as a promising cellular therapeutic strategy for the management of graft-versus-host disease
    • J. P. McGuirk, J. R. Smith, C. L. Divine, M. Zuniga, and M. L. Weiss, "Wharton's Jelly-derived mesenchymal stromal cells as a promising cellular therapeutic strategy for the management of graft-versus-host disease," Pharmaceuticals, vol. 8, no. 2, pp. 196-220, 2015.
    • (2015) Pharmaceuticals , vol.8 , Issue.2 , pp. 196-220
    • McGuirk, J.P.1    Smith, J.R.2    Divine, C.L.3    Zuniga, M.4    Weiss, M.L.5
  • 10
    • 79959938424 scopus 로고    scopus 로고
    • Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells
    • T. Deuse, M. Stubbendorff, K. Tang-Quan et al., "Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells," Cell Transplantation, vol. 20, no. 5, pp. 655-667, 2011.
    • (2011) Cell Transplantation , vol.20 , Issue.5 , pp. 655-667
    • Deuse, T.1    Stubbendorff, M.2    Tang-Quan, K.3
  • 11
    • 70349121293 scopus 로고    scopus 로고
    • Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues
    • K. H. Yoo, I. K. Jang, M. W. Lee et al., "Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues," Cellular Immunology, vol. 259, no. 2, pp. 150-156, 2009.
    • (2009) Cellular Immunology , vol.259 , Issue.2 , pp. 150-156
    • Yoo, K.H.1    Jang, I.K.2    Lee, M.W.3
  • 12
    • 78149265779 scopus 로고    scopus 로고
    • Adipose-tissue-derived and Wharton's jelly-derived mesenchymal stromal cells suppress lymphocyte responses by secreting leukemia inhibitory factor
    • M. Najar, G. Raicevic, H. I. Boufker et al., "Adipose-tissue-derived and Wharton's jelly-derived mesenchymal stromal cells suppress lymphocyte responses by secreting leukemia inhibitory factor," Tissue Engineering Part A, vol. 16, no. 11, pp. 3537-3546, 2010.
    • (2010) Tissue Engineering Part A , vol.16 , Issue.11 , pp. 3537-3546
    • Najar, M.1    Raicevic, G.2    Boufker, H.I.3
  • 13
    • 77949308137 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines, IFNγ and TNFα, influence immune properties of human bone marrow and wharton jelly mesenchymal stem cells differentially
    • S. J. Prasanna, D. Gopalakrishnan, S. R. Shankar, and A. B. Vasandan, "Pro-inflammatory cytokines, IFNγ and TNFα, influence immune properties of human bone marrow and wharton jelly mesenchymal stem cells differentially," PLoS ONE, vol. 5, no. 2, article e9016, 2010.
    • (2010) PLoS ONE , vol.5 , Issue.2
    • Prasanna, S.J.1    Gopalakrishnan, D.2    Shankar, S.R.3    Vasandan, A.B.4
  • 14
    • 56249139741 scopus 로고    scopus 로고
    • Immune properties of human umbilical cord Wharton's jelly-derived cells
    • M. L. Weiss, C. Anderson, S. Medicetty et al., "Immune properties of human umbilical cord Wharton's jelly-derived cells," STEM CELLS, vol. 26, no. 11, pp. 2865-2874, 2008.
    • (2008) Stem Cells , vol.26 , Issue.11 , pp. 2865-2874
    • Weiss, M.L.1    Anderson, C.2    Medicetty, S.3
  • 16
    • 68749116404 scopus 로고    scopus 로고
    • A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering
    • L. Wang, I. Tran, K. Seshareddy, M. L. Weiss, and M. S. Detamore, "A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering," Tissue Engineering Part A, vol. 15, no. 8, pp. 2259-2266, 2009.
    • (2009) Tissue Engineering Part A , vol.15 , Issue.8 , pp. 2259-2266
    • Wang, L.1    Tran, I.2    Seshareddy, K.3    Weiss, M.L.4    Detamore, M.S.5
  • 17
    • 84959085088 scopus 로고    scopus 로고
    • Standardizing umbilical cord mesenchymal stromal cells for translation to clinical use: Selection of GMP-compliant medium and a simplified isolation method
    • In press
    • J. R. Smith, K. Pfeiffer, F. Petry, N. Powell, J. Delzeit, and M. L. Weiss, "Standardizing umbilical cord mesenchymal stromal cells for translation to clinical use: selection of GMP-compliant medium and a simplified isolation method," Stem Cells International, In press.
    • Stem Cells International
    • Smith, J.R.1    Pfeiffer, K.2    Petry, F.3    Powell, N.4    Delzeit, J.5    Weiss, M.L.6
  • 18
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • M. Dominici, K. Le Blanc, I. Mueller et al., "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement," Cytotherapy, vol. 8, no. 4, pp. 315-317, 2006.
    • (2006) Cytotherapy , vol.8 , Issue.4 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 19
    • 0037237389 scopus 로고    scopus 로고
    • Matrix cells from Wharton's jelly form neurons and glia
    • K. E. Mitchell, M. L. Weiss, B. M. Mitchell et al., "Matrix cells from Wharton's jelly form neurons and glia," STEM CELLS, vol. 21, no. 1, pp. 50-60, 2003.
    • (2003) Stem Cells , vol.21 , Issue.1 , pp. 50-60
    • Mitchell, K.E.1    Weiss, M.L.2    Mitchell, B.M.3
  • 21
    • 33744973827 scopus 로고    scopus 로고
    • Human umbilical cord matrix stem cells: Preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease
    • M. L. Weiss, S. Medicetty, A. R. Bledsoe et al., "Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease," Stem Cells, vol. 24, no. 3, pp. 781-792, 2006.
    • (2006) Stem Cells , vol.24 , Issue.3 , pp. 781-792
    • Weiss, M.L.1    Medicetty, S.2    Bledsoe, A.R.3
  • 22
    • 13744254666 scopus 로고    scopus 로고
    • Human umbilical cord perivascular (HUCPV) cells: A source of mesenchymal progenitors
    • R. Sarugaser, D. Lickorish, D. Baksh, M. M. Hosseini, and J. E. Davies, "Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors," Stem Cells, vol. 23, no. 2, pp. 220-229, 2005.
    • (2005) Stem Cells , vol.23 , Issue.2 , pp. 220-229
    • Sarugaser, R.1    Lickorish, D.2    Baksh, D.3    Hosseini, M.M.4    Davies, J.E.5
  • 23
    • 39049164672 scopus 로고    scopus 로고
    • Islet-like clusters derived from mesenchymal stem cells in Wharton's jelly of the human umbilical cord for transplantation to control type 1 diabetes
    • K. C. Chao, K. F. Chao, Y. S. Fu, and S. H. Liu, "Islet-like clusters derived from mesenchymal stem cells in Wharton's jelly of the human umbilical cord for transplantation to control type 1 diabetes," PLoS ONE, vol. 3, no. 1, Article ID e1451, 2008.
    • (2008) PLoS ONE , vol.3 , Issue.1
    • Chao, K.C.1    Chao, K.F.2    Fu, Y.S.3    Liu, S.H.4
  • 24
    • 79959973362 scopus 로고    scopus 로고
    • Human umbilical mesenchymal stem cells promote recovery after ischemic stroke
    • Y.-C. Lin, T.-L. Ko, Y.-H. Shih et al., "Human umbilical mesenchymal stem cells promote recovery after ischemic stroke," Stroke, vol. 42, no. 7, pp. 2045-2053, 2011.
    • (2011) Stroke , vol.42 , Issue.7 , pp. 2045-2053
    • Lin, Y.-C.1    Ko, T.-L.2    Shih, Y.-H.3
  • 25
    • 84888258395 scopus 로고    scopus 로고
    • Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2
    • H.-S. Kim, T.-H. Shin, B.-C. Lee et al., "Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2," Gastroenterology, vol. 145, no. 6, pp. 1392-1403, 2013.
    • (2013) Gastroenterology , vol.145 , Issue.6 , pp. 1392-1403
    • Kim, H.-S.1    Shin, T.-H.2    Lee, B.-C.3
  • 26
    • 10444248938 scopus 로고    scopus 로고
    • Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord
    • H.-S. Wang, S.-C. Hung, S.-T. Peng et al., "Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord," STEM CELLS, vol. 22, no. 7, pp. 1330-1337, 2004.
    • (2004) Stem Cells , vol.22 , Issue.7 , pp. 1330-1337
    • Wang, H.-S.1    Hung, S.-C.2    Peng, S.-T.3
  • 27
    • 33645532494 scopus 로고    scopus 로고
    • Conversion of human umbilical cord mesenchymal stem cells in Wharton's Jelly to dopaminergic neurons in vitro: Potential therapeutic application for Parkinsonism
    • Y.-S. Fu, Y.-C. Cheng, M.-Y. A. Lin et al., "Conversion of human umbilical cord mesenchymal stem cells in Wharton's Jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism," Stem Cells, vol. 24, no. 1, pp. 115-124, 2006.
    • (2006) Stem Cells , vol.24 , Issue.1 , pp. 115-124
    • Fu, Y.-S.1    Cheng, Y.-C.2    Lin, M.-Y.A.3
  • 28
    • 4444373354 scopus 로고    scopus 로고
    • Transformation of human umbilical mesenchymal cells into neurons in vitro
    • Y.-S. Fu, Y.-T. Shih, Y.-C. Cheng, and M.-Y. Min, "Transformation of human umbilical mesenchymal cells into neurons in vitro," Journal of Biomedical Science, vol. 11, no. 5, pp. 652-660, 2004.
    • (2004) Journal of Biomedical Science , vol.11 , Issue.5 , pp. 652-660
    • Fu, Y.-S.1    Shih, Y.-T.2    Cheng, Y.-C.3    Min, M.-Y.4
  • 29
    • 84877070464 scopus 로고    scopus 로고
    • Wharton's jelly or bone marrow mesenchymal stromal cells improve cardiac function following myocardial infarction for more than 32 weeks in a rat model: A preliminary report
    • Y. López, B. Lutjemeier, K. Seshareddy et al., "Wharton's jelly or bone marrow mesenchymal stromal cells improve cardiac function following myocardial infarction for more than 32 weeks in a rat model: a preliminary report," Current Stem Cell Research and Therapy, vol. 8, no. 1, pp. 46-59, 2013.
    • (2013) Current Stem Cell Research and Therapy , vol.8 , Issue.1 , pp. 46-59
    • López, Y.1    Lutjemeier, B.2    Seshareddy, K.3
  • 30
    • 79951679002 scopus 로고    scopus 로고
    • Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
    • M. E. Bernardo, L. M. Ball, A. M. Cometa et al., "Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation," Bone Marrow Transplantation, vol. 46, no. 2, pp. 200-207, 2011.
    • (2011) Bone Marrow Transplantation , vol.46 , Issue.2 , pp. 200-207
    • Bernardo, M.E.1    Ball, L.M.2    Cometa, A.M.3
  • 31
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • K. Le Blanc, F. Frassoni, L. Ball et al., "Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study," The Lancet, vol. 371, no. 9624, pp. 1579-1586, 2008.
    • (2008) The Lancet , vol.371 , Issue.9624 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 32
    • 84886404127 scopus 로고    scopus 로고
    • Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease
    • L. M. Ball, M. E. Bernardo, H. Roelofs et al., "Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease," British Journal of Haematology, vol. 163, no. 4, pp. 501-509, 2013.
    • (2013) British Journal of Haematology , vol.163 , Issue.4 , pp. 501-509
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3
  • 33
    • 84883375670 scopus 로고    scopus 로고
    • Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem cell transplantation
    • R. Jitschin, D. Mougiakakos, L. von Bahr et al., "Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem cell transplantation," Stem Cells, vol. 31, no. 8, pp. 1715-1725, 2013.
    • (2013) Stem Cells , vol.31 , Issue.8 , pp. 1715-1725
    • Jitschin, R.1    Mougiakakos, D.2    Von Bahr, L.3
  • 34
    • 84922553044 scopus 로고    scopus 로고
    • Increasing efficiency of human mesenchymal stromal cell culture by optimization of microcarrier concentration and design of medium feed
    • A. K.-L. Chen, Y. K. Chew, H. Y. Tan, S. Reuveny, and S. K. W. Oh, "Increasing efficiency of human mesenchymal stromal cell culture by optimization of microcarrier concentration and design of medium feed," Cytotherapy, vol. 17, no. 2, pp. 163-173, 2015.
    • (2015) Cytotherapy , vol.17 , Issue.2 , pp. 163-173
    • Chen, A.K.-L.1    Chew, Y.K.2    Tan, H.Y.3    Reuveny, S.4    Oh, S.K.W.5
  • 35
    • 84899649027 scopus 로고    scopus 로고
    • A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells
    • F. Dos Santos, A. Campbell, A. Fernandes-Platzgummer et al., "A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells," Biotechnology and Bioengineering, vol. 111, no. 6, pp. 1116-1127, 2014.
    • (2014) Biotechnology and Bioengineering , vol.111 , Issue.6 , pp. 1116-1127
    • Dos Santos, F.1    Campbell, A.2    Fernandes-Platzgummer, A.3
  • 37
    • 84925268082 scopus 로고    scopus 로고
    • Modulation of mesenchymal stromal cell characteristics by microcarrier culture in bioreactors
    • J. Hupfeld, I. H. Gorr, C. Schwald et al., "Modulation of mesenchymal stromal cell characteristics by microcarrier culture in bioreactors," Biotechnology and Bioengineering, vol. 111, no. 11, pp. 2290-2302, 2014.
    • (2014) Biotechnology and Bioengineering , vol.111 , Issue.11 , pp. 2290-2302
    • Hupfeld, J.1    Gorr, I.H.2    Schwald, C.3
  • 38
    • 34547122719 scopus 로고    scopus 로고
    • Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow
    • D. Baksh, R. Yao, and R. S. Tuan, "Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow," Stem Cells, vol. 25, no. 6, pp. 1384-1392, 2007.
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1384-1392
    • Baksh, D.1    Yao, R.2    Tuan, R.S.3
  • 39
    • 78751641526 scopus 로고    scopus 로고
    • Growth and differentiation properties of mesenchymal stromal cell populations derived from whole human umbilical cord
    • I. Majore, P. Moretti, F. Stahl, R. Hass, and C. Kasper, "Growth and differentiation properties of mesenchymal stromal cell populations derived from whole human umbilical cord," Stem Cell Reviews and Reports, vol. 7, no. 1, pp. 17-31, 2011.
    • (2011) Stem Cell Reviews and Reports , vol.7 , Issue.1 , pp. 17-31
    • Majore, I.1    Moretti, P.2    Stahl, F.3    Hass, R.4    Kasper, C.5
  • 40
    • 0026254349 scopus 로고
    • Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor
    • S. S. Ozturk and B. O. Palsson, "Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor," Biotechnology Progress, vol. 7, no. 6, pp. 481-494, 1991.
    • (1991) Biotechnology Progress , vol.7 , Issue.6 , pp. 481-494
    • Ozturk, S.S.1    Palsson, B.O.2
  • 41
    • 0028500473 scopus 로고
    • Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures
    • J. Ljunggren and L. Häggström, "Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures," Biotechnology and Bioengineering, vol. 44, no. 7, pp. 808-818, 1994.
    • (1994) Biotechnology and Bioengineering , vol.44 , Issue.7 , pp. 808-818
    • Ljunggren, J.1    Häggström, L.2
  • 42
    • 0023763120 scopus 로고
    • Catabolic control of mammalian cell culture
    • M. W. Glacken, "Catabolic control of mammalian cell culture," Bio/Technology, vol. 6, no. 9, pp. 1041-1050, 1988.
    • (1988) Bio/Technology , vol.6 , Issue.9 , pp. 1041-1050
    • Glacken, M.W.1
  • 43
    • 0000409606 scopus 로고
    • Spontaneous decomposition of glutamine in cell culture media
    • G. L. Tritsch and G. E. Moore, "Spontaneous decomposition of glutamine in cell culture media," Experimental Cell Research, vol. 28, no. 2, pp. 360-364, 1962.
    • (1962) Experimental Cell Research , vol.28 , Issue.2 , pp. 360-364
    • Tritsch, G.L.1    Moore, G.E.2
  • 44
    • 0031239859 scopus 로고    scopus 로고
    • Effects of ammonium and lactate on growth and metabolism of a recombinant Chinese hamster ovary cell culture
    • M.-S. Lao and D. Toth, "Effects of ammonium and lactate on growth and metabolism of a recombinant Chinese hamster ovary cell culture," Biotechnology Progress, vol. 13, no. 5, pp. 688-691, 1997.
    • (1997) Biotechnology Progress , vol.13 , Issue.5 , pp. 688-691
    • Lao, M.-S.1    Toth, D.2
  • 45
    • 84885986075 scopus 로고    scopus 로고
    • Microcarrier culture for efficient expansion and osteogenic differentiation of human fetal mesenchymal stem cells
    • T. K. Goh, Z. Zhang, A. K. Chen et al., "Microcarrier culture for efficient expansion and osteogenic differentiation of human fetal mesenchymal stem cells," BioResearch Open Access, vol. 2, no. 2, pp. 84-97, 2013.
    • (2013) BioResearch Open Access , vol.2 , Issue.2 , pp. 84-97
    • Goh, T.K.1    Zhang, Z.2    Chen, A.K.3
  • 46
    • 80055102439 scopus 로고    scopus 로고
    • Spontaneous osteogenesis of MSCs cultured on 3D microcarriers through alteration of cytoskeletal tension
    • P.-C. Tseng, T.-H. Young, T.-M. Wang, H.-W. Peng, S.-M. Hou, and M.-L. Yen, "Spontaneous osteogenesis of MSCs cultured on 3D microcarriers through alteration of cytoskeletal tension," Biomaterials, vol. 33, no. 2, pp. 556-564, 2012.
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 556-564
    • Tseng, P.-C.1    Young, T.-H.2    Wang, T.-M.3    Peng, H.-W.4    Hou, S.-M.5    Yen, M.-L.6
  • 47
    • 79961052652 scopus 로고    scopus 로고
    • Spektrum Akademischer, Heidelberg, Germany, 3rd edition
    • H. Chmiel, Bioprozesstechnik, Spektrum Akademischer, Heidelberg, Germany, 3rd edition, 2011.
    • (2011) Bioprozesstechnik
    • Chmiel, H.1
  • 48
    • 0022059389 scopus 로고
    • A mechanistic analysis of the inoculum requirement for the cultivation of mammalian cells on microcarriers
    • W. S. Hu, J. Meier, and D. I. C. Wang, "A mechanistic analysis of the inoculum requirement for the cultivation of mammalian cells on microcarriers," Biotechnology and Bioengineering, vol. 27, no. 5, pp. 585-595, 1985.
    • (1985) Biotechnology and Bioengineering , vol.27 , Issue.5 , pp. 585-595
    • Hu, W.S.1    Meier, J.2    Wang, D.I.C.3
  • 49
    • 24944494021 scopus 로고    scopus 로고
    • Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells
    • C. Götherström, A. West, J. Liden, M. Uzunel, R. Lahesmaa, and K. Le Blanc, "Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells," Haematologica, vol. 90, no. 8, pp. 1017-1026, 2005.
    • (2005) Haematologica , vol.90 , Issue.8 , pp. 1017-1026
    • Götherström, C.1    West, A.2    Liden, J.3    Uzunel, M.4    Lahesmaa, R.5    Le Blanc, K.6


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