Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display

Methods in Enzymology

Volumn 570, Issue , 2016, Pages 47-72

  Dorgham, Karim ^a   Cerini, Fabrice ^b   Gaertner, Hubert ^b   Melotti, Astrid ^b   Rossitto Borlat, Irène ^b   Gorochov, Guy ^a,b   Hartley, Oliver ^c  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

CCR5; Chemokine; CX3CR1; Phage display; Pharmacology

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; DNA; CCR5 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR5; CX3CR1 PROTEIN, HUMAN; PEPTIDE LIBRARY;

BINDING AFFINITY; CELL LINE; CELL MIGRATION; CELL SURFACE; DNA PURIFICATION; ESCHERICHIA COLI; GENE AMPLIFICATION; INTRACELLULAR SIGNALING; MOLECULAR LIBRARY; NONHUMAN; PHAGE DISPLAY; POLYMERASE CHAIN REACTION; PROTEIN FUNCTION; PROTEIN STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR BIOLOGY; PEPTIDE LIBRARY; PROCEDURES;

CELL LINE; CHEMOKINES; HUMANS; MOLECULAR BIOLOGY; PEPTIDE LIBRARY; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE;

EID: 84959095228     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/bs.mie.2015.09.014     Document Type: Chapter

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