Short- and Long-Term Outcomes of Moderate and Late Preterm Infants

American Journal of Perinatology

Volumn 33, Issue 3, 2016, Pages 305-317

  Natarajan, Girija ^a   Shankaran, Seetha ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

late preterm; moderate preterm; neurodevelopmental outcomes; outcomes

Indexed keywords

BRAIN DEVELOPMENT; BRAIN HEMORRHAGE; BRAIN INJURY; CHILD GROWTH; COGNITION; FEEDING DIFFICULTY; GESTATIONAL AGE; GLUCOSE METABOLISM; HEALTH HAZARD; HOSPITAL READMISSION; HUMAN; INFANT; INFANT FEEDING; INFANT MORTALITY; INFECTION; JAUNDICE; LEUKOMALACIA; META ANALYSIS (TOPIC); METABOLIC REGULATION; MULTICENTER STUDY (TOPIC); NEWBORN APNEA; NEWBORN PERIOD; PERIVENTRICULAR LEUKOMALACIA; PREGNANCY OUTCOME; PREMATURITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY FUNCTION; RESPIRATORY TRACT DISEASE; REVIEW; SYSTEMATIC REVIEW (TOPIC); THERMOREGULATION; FEMALE; GROWTH, DEVELOPMENT AND AGING; INFANT NUTRITION; INFANT, PREMATURE, DISEASES; MORBIDITY; NEWBORN; PREGNANCY; PREMATURE BIRTH; TREATMENT OUTCOME;

FEMALE; GESTATIONAL AGE; HUMANS; INFANT; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MORBIDITY; PREGNANCY; PREMATURE BIRTH; TREATMENT OUTCOME;

EID: 84959090908     PISSN: 07351631     EISSN: 10988785     Source Type: Journal    
DOI: 10.1055/s-0035-1571150     Document Type: Review

References (95)

1. Raju T. NK, Higgins R. D., Stark A. R., Leveno K. J. Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics: 2006; 118 3 1207 1214
2. Davidoff M. J., Dias T., Damus K., et al. Changes in the gestational age distribution among U.S. singleton births: impact on rates of late preterm birth, 1992 to 2002. Semin Perinatol: 2006; 30 1 8 15
3. Blencowe H., Cousens S., Oestergaard M. Z., et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet: 2012; 379 9832 2162 2172
4. Shapiro-Mendoza C. K., Lackritz E. M. Epidemiology of late and moderate preterm birth. Semin Fetal Neonatal Med: 2012; 17 3 120 125
5. Gouyon J. B., Iacobelli S., Ferdynus C., Bonsante F. Neonatal problems of late and moderate preterm infants. Semin Fetal Neonatal Med: 2012; 17 3 146 152
6. Boyle J. D., Boyle E. M. Born just a few weeks early: does it matter? Arch Dis Child Fetal Neonatal Ed: 2013; 98 1 F85 F88
7. Escobar G. J., Clark R. H., Greene J. D. Short-term outcomes of infants born at 35 and 36 weeks gestation: we need to ask more questions. Semin Perinatol: 2006; 30 1 28 33
8. Escobar G. J., McCormick M. C., Zupancic J. A., et al. Unstudied infants: outcomes of moderately premature infants in the neonatal intensive care unit. Arch Dis Child Fetal Neonatal Ed: 2006; 91 4 F238 F244
9. Teune M. J., Bakhuizen S., Gyamfi Bannerman C., et al. A systematic review of severe morbidity in infants born late preterm. Am J Obstet Gynecol: 2011; 205 4 374.e1 374.e9
10. Colin A. A., McEvoy C., Castile R. G. Respiratory morbidity and lung function in preterm infants of 32 to 36 weeks' gestational age. Pediatrics: 2010; 126 1 115 128
11. Hibbard J. U., Wilkins I., Sun L., et al. Consortium on Safe Labor. Respiratory morbidity in late preterm births. JAMA: 2010; 304 4 419 425
12. Mahoney A. D., Jain L. Respiratory disorders in moderately preterm, late preterm, and early term infants. Clin Perinatol: 2013; 40 4 665 678
13. Sahni R., Polin R. A. Physiologic underpinnings for clinical problems in moderately preterm and late preterm infants. Clin Perinatol: 2013; 40 4 645 663
14. Rubaltelli F. F., Dani C., Reali M. F., et al. Acute neonatal respiratory distress in Italy: a one-year prospective study Italian Group of Neonatal Pneumology. Acta Paediatr: 1998; 87 12 1261 1268
15. Gouyon J. B., Vintejoux A., Sagot P., Burguet A., Quantin C., Ferdynus C.; Burgundy Perinatal Network. Neonatal outcome associated with singleton birth at 34-41 weeks of gestation. Int J Epidemiol: 2010; 39 3 769 776
16. McIntire D. D., Leveno K. J. Neonatal mortality and morbidity rates in late preterm births compared with births at term. Obstet Gynecol: 2008; 111 1 35 41
17. Ramachandrappa A., Jain L. Elective cesarean section: its impact on neonatal respiratory outcome. Clin Perinatol: 2008; 35 2 373 393, vii
18. ACOG Committee on Obstetric Practice ACOG Committee Opinion No. 475: antenatal corticosteroid therapy for fetal maturation. Obstet Gynecol: 2011; 117 (2, Pt 1): 422 424
19. Roberts D., Dalziel S. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev: 2006; 3 CD004454
20. Gyamfi-Bannerman C., Gilbert S., Landon M. B., et al. Eunice Kennedy Shriver National Institute of Child Health; Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU). Effect of antenatal corticosteroids on respiratory morbidity in singletons after late-preterm birth. Obstet Gynecol: 2012; 119 3 555 559
21. Porto A. M., Coutinho I. C., Correia J. B., Amorim M. M. Effectiveness of antenatal corticosteroids in reducing respiratory disorders in late preterm infants: randomised clinical trial. BMJ: 2011; 342 d1696
22. Raju T. N. Developmental physiology of late and moderate prematurity. Semin Fetal Neonatal Med: 2012; 17 3 126 131
23. Wang M. L., Dorer D. J., Fleming M. P., Catlin E. A. Clinical outcomes of near-term infants. Pediatrics: 2004; 114 2 372 376
24. Kalyoncu O., Aygün C., Cetinoʇlu E., Küçüködük S. Neonatal morbidity and mortality of late-preterm babies. J Matern Fetal Neonatal Med: 2010; 23 7 607 612
25. Bird T. M., Bronstein J. M., Hall R. W., Lowery C. L., Nugent R., Mays G. P. Late preterm infants: birth outcomes and health care utilization in the first year. Pediatrics: 2010; 126 2 e311 e319
26. Laptook A., Jackson G. L. Cold stress and hypoglycemia in the late preterm (near-term) infant: impact on nursery of admission. Semin Perinatol: 2006; 30 1 24 27
27. Altman M., Vanpée M., Cnattingius S., Norman M. Neonatal morbidity in moderately preterm infants: a Swedish national population-based study. J Pediatr: 2011; 158 2 239 44.e1
28. Adamkin D. H.; Committee on Fetus and Newborn. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics: 2011; 127 3 575 579
29. Bhutani V. K., Johnson L. Kernicterus in late preterm infants cared for as term healthy infants. Semin Perinatol: 2006; 30 2 89 97
30. Maisels M. J., Bhutani V. K., Bogen D., Newman T. B., Stark A. R., Watchko J. F. Hyperbilirubinemia in the newborn infant > or =35 weeks' gestation: an update with clarifications. Pediatrics: 2009; 124 4 1193 1198
31. Walsh M., Laptook A., Stoll B., Shankaran S., Kandefer S., Cook N. The Spectrum of Mortality and Morbidity in Moderate Preterm Infants (MPT). Paper presented at Annual Meeting of Society of Pediatric Research/Pediatric Academic Societies; May 2014; Vancouver, Canada
32. Khashu M., Narayanan M., Bhargava S., Osiovich H. Perinatal outcomes associated with preterm birth at 33 to 36 weeks' gestation: a population-based cohort study. Pediatrics: 2009; 123 1 109 113
33. Cohen-Wolkowiez M., Moran C., Benjamin D. K., et al. Early and late onset sepsis in late preterm infants. Pediatr Infect Dis J: 2009; 28 12 1052 1056
34. Bhat V., Karam M., Saslow J., et al. Utility of performing routine head ultrasounds in preterm infants with gestational age 30-34 weeks. J Matern Fetal Neonatal Med: 2012; 25 2 116 119
35. Natarajan G., Shankaran S., Saha S., et al. Abnormal Cranial Imaging in Moderately Preterm (MPT) infants in the NICU. Paper presented at Annual Meeting of Society of Pediatric Research/Pediatric Academic Societies; May 2015, San Diego, CA
36. Kirkby S., Greenspan J. S., Kornhauser M., Schneiderman R. Clinical outcomes and cost of the moderately preterm infant. Adv Neonatal Care: 2007; 7 2 80 87
37. Batton D. G., Holtrop P., DeWitte D., Pryce C., Roberts C. Current gestational age-related incidence of major intraventricular hemorrhage. J Pediatr: 1994; 125 4 623 625
38. Harris N. J., Palacio D., Ginzel A., Richardson C. J., Swischuk L. Are routine cranial ultrasounds necessary in premature infants greater than 30 weeks gestation? Am J Perinatol: 2007; 24 1 17 21
39. Kelly C. E., Cheong J. LY, Gabra Fam L., et al. Moderate and late preterm infants exhibit widespread brain white matter microstructure alterations at term-equivalent age relative to term-born controls. Brain Imaging Behav: 2015; (e-pub ahead of print).doi:10.1007/s11682-015-9361-0
40. Walsh J. M., Doyle L. W., Anderson P. J., Lee K. J., Cheong J. L. Moderate and late preterm birth: effect on brain size and maturation at term-equivalent age. Radiology: 2014; 273 1 232 240
41. Vohr B. Long-term outcomes of moderately preterm, late preterm, and early term infants. Clin Perinatol: 2013; 40 4 739 751
42. Bhutta A. T., Cleves M. A., Casey P. H., Cradock M. M., Anand K. J. Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis. JAMA: 2002; 288 6 728 737
43. McGowan J. E., Alderdice F. A., Holmes V. A., Johnston L. Early childhood development of late-preterm infants: a systematic review. Pediatrics: 2011; 127 6 1111 1124
44. Baron I. S., Erickson K., Ahronovich M. D., Coulehan K., Baker R., Litman F. R. Visuospatial and verbal fluency relative deficits in 'complicated' late-preterm preschool children. Early Hum Dev: 2009; 85 12 751 754
45. Morse S. B., Zheng H., Tang Y., Roth J. Early school-age outcomes of late preterm infants. Pediatrics: 2009; 123 4 e622 e629
46. Petrini J. R., Dias T., McCormick M. C., Massolo M. L., Green N. S., Escobar G. J. Increased risk of adverse neurological development for late preterm infants. J Pediatr: 2009; 154 2 169 176
47. Chyi L. J., Lee H. C., Hintz S. R., Gould J. B., Sutcliffe T. L. School outcomes of late preterm infants: special needs and challenges for infants born at 32 to 36 weeks gestation. J Pediatr: 2008; 153 1 25 31
48. Huddy C. L., Johnson A., Hope P. L. Educational and behavioural problems in babies of 32-35 weeks gestation. Arch Dis Child Fetal Neonatal Ed: 2001; 85 1 F23 F28
49. Moster D., Lie R. T., Markestad T. Long-term medical and social consequences of preterm birth. N Engl J Med: 2008; 359 3 262 273
50. Gyamfi C. Neonatal and developmental outcomes in children born in the late preterm period versus term. Am J Obstet Gynecol: 2008; 199 (6, Suppl A): S45
51. Marret S., Ancel P. Y., Marpeau L., et al. Epipage Study Group. Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation. Obstet Gynecol: 2007; 110 1 72 80
52. Santos I. S., Matijasevich A., Domingues M. R., Barros A. J., Victora C. G., Barros F. C. Late preterm birth is a risk factor for growth faltering in early childhood: a cohort study. BMC Pediatr: 2009; 9 71 78
53. Odd D. E., Emond A., Whitelaw A. Long-term cognitive outcomes of infants born moderately and late preterm. Dev Med Child Neurol: 2012; 54 8 704 709
54. Gurka M. J., LoCasale-Crouch J., Blackman J. A. Long-term cognition, achievement, socioemotional, and behavioral development of healthy late-preterm infants. Arch Pediatr Adolesc Med: 2010; 164 6 525 532
55. MacKay D. F., Smith G. C., Dobbie R., Pell J. P. Gestational age at delivery and special educational need: retrospective cohort study of 407,503 schoolchildren. PLoS Med: 2010; 7 6 e1000289
56. Baron I. S., Erickson K., Ahronovich M. D., Litman F. R., Brandt J. Spatial location memory discriminates children born at extremely low birth weight and late-preterm at age three. Neuropsychology: 2010; 24 6 787 794
57. Kerstjens J. M., Butcher P. R., Molen van der J. L., et al. Development of late preterm infants at age 4. [Abstract] Eur J Public Health: 2007; 17 02 104 105
58. Woythaler M. A., McCormick M. C., Smith V. C. Late preterm infants have worse 24-month neurodevelopmental outcomes than term infants. Pediatrics: 2011; 127 3 e622 e629
59. Talge N. M., Holzman C., Wang J., Lucia V., Gardiner J., Breslau N. Late-preterm birth and its association with cognitive and socioemotional outcomes at 6 years of age. Pediatrics: 2010; 126 6 1124 1131
60. Woythaler M., McCormick M. C., Mao W. Y., Smith V. C. Late preterm infants and neurodevelopmental outcomes at kindergarten. Pediatrics: 2015; 136 3 424 431
61. Blaggan S., Guy A., Boyle E. M., et al. A parent questionnaire for developmental screening in infants born late and moderately preterm. Pediatrics: 2014; 134 1 e55 e62
62. Cserjesi R., Van Braeckel K. NJA, Butcher P. R., et al. Functioning of 7-year-old children born at 32 to 35 weeks' gestational age. Pediatrics: 2012; 130 4 e838 e846
63. Quigley M. A., Poulsen G., Boyle E., et al. Early term and late preterm birth are associated with poorer school performance at age 5 years: a cohort study. Arch Dis Child Fetal Neonatal Ed: 2012; 97 3 F167 F173
64. Mathiasen R., Hansen B. M., Andersen A. M., Forman J. L., Greisen G. Gestational age and basic school achievements: a national follow-up study in Denmark. Pediatrics: 2010; 126 6 e1553 e1561
65. Nepomnyaschy L., Hegyi T., Ostfeld B. M., Reichman N. E. Developmental outcomes of late-preterm infants at 2 and 4 years. Matern Child Health J: 2012; 16 8 1612 1624
66. Johnson S., Evans T. A., Draper E. S., et al. Neurodevelopmental outcomes following late and moderate prematurity: a population-based cohort study. Arch Dis Child Fetal Neonatal Ed: 2015; 100 F301 F308
67. Roth J., Figlio D. N., Chen Y., et al. Maternal and infant factors associated with excess kindergarten costs. Pediatrics: 2004; 114 3 720 728
68. Lipkind H. S., Slopen M. E., Pfeiffer M. R., McVeigh K. H. School-age outcomes of late preterm infants in New York City. Am J Obstet Gynecol: 2012; 206 3 222.e1 222.e6
69. Romeo D. M., Di Stefano A., Conversano M., et al. Neurodevelopmental outcome at 12 and 18 months in late preterm infants. Eur J Paediatr Neurol: 2010; 14 6 503 507
70. de Jong M., Verhoeven M., van Baar A. L. School outcome, cognitive functioning, and behaviour problems in moderate and late preterm children and adults: a review. Semin Fetal Neonatal Med: 2012; 17 3 163 169
71. Eide M. G., Oyen N., Skjaerven R., Bjerkedal T. Associations of birth size, gestational age, and adult size with intellectual performance: evidence from a cohort of Norwegian men. Pediatr Res: 2007; 62 5 636 642
72. Ekeus C., Lindström K., Lindblad F., Rasmussen F., Hjern A. Preterm birth, social disadvantage, and cognitive competence in Swedish 18- to 19-year-old men. Pediatrics: 2010; 125 1 e67 e73
73. Potijk M. R., de Winter A. F., Bos A. F., Kerstjens J. M., Reijneveld S. A. Higher rates of behavioural and emotional problems at preschool age in children born moderately preterm. Arch Dis Child: 2012; 97 2 112 117
74. van Baar A. L., Vermaas J., Knots E., de Kleine M. J., Soons P. Functioning at school age of moderately preterm children born at 32 to 36 weeks' gestational age. Pediatrics: 2009; 124 1 251 257
75. Lindström K., Lindblad F., Hjern A. Psychiatric morbidity in adolescents and young adults born preterm: a Swedish national cohort study. Pediatrics: 2009; 123 1 e47 e53
76. Dalziel S. R., Lim V. K., Lambert A., et al. Psychological functioning and health-related quality of life in adulthood after preterm birth. Dev Med Child Neurol: 2007; 49 8 597 602
77. Escobar G. J., Greene J. D., Hulac P., et al. Rehospitalisation after birth hospitalisation: patterns among infants of all gestations. Arch Dis Child: 2005; 90 2 125 131
78. McLaurin K. K., Hall C. B., Jackson E. A., Owens O. V., Mahadevia P. J. Persistence of morbidity and cost differences between late-preterm and term infants during the first year of life. Pediatrics: 2009; 123 2 653 659
79. Martens P. J., Derksen S., Gupta S. Predictors of hospital readmission of Manitoba newborns within six weeks postbirth discharge: a population-based study. Pediatrics: 2004; 114 3 708 713
80. Shapiro-Mendoza C. K., Tomashek K. M., Kotelchuck M., Barfield W., Weiss J., Evans S. Risk factors for neonatal morbidity and mortality among healthy, late preterm newborns. Semin Perinatol: 2006; 30 2 54 60
81. Oddie S. J., Hammal D., Richmond S., Parker L. Early discharge and readmission to hospital in the first month of life in the Northern Region of the UK during 1998: a case cohort study. Arch Dis Child: 2005; 90 2 119 124
82. Tomashek K. M., Shapiro-Mendoza C. K., Weiss J., et al. Early discharge among late preterm and term newborns and risk of neonatal morbidity. Semin Perinatol: 2006; 30 2 61 68
83. Kuzniewicz M. W., Parker S. J., Schnake-Mahl A., Escobar G. J. Hospital readmissions and emergency department visits in moderate preterm, late preterm, and early term infants. Clin Perinatol: 2013; 40 4 753 775
84. Escobar G. J., Joffe S., Gardner M. N., Armstrong M. A., Folck B. F., Carpenter D. M. Rehospitalization in the first two weeks after discharge from the neonatal intensive care unit. Pediatrics: 1999; 104 1 e2
85. Boyle E. M., Poulsen G., Field D. J., et al. Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study. BMJ: 2012; 344 e896
86. Olabarrieta I., Gonzalez-Carrasco E., Calvo C., Pozo F., Casas I., García-García M. L. Hospital admission due to respiratory viral infections in moderate preterm, late preterm and term infants during their first year of life. Allergol Immunopathol (Madr): 2015; 43 5 469 473
87. Paranjothy S., Dunstan F., Watkins W. J., et al. Gestational age, birth weight, and risk of respiratory hospital admission in childhood. Pediatrics: 2013; 132 6 e1562 e1569
88. Harijan P., Boyle E. M. Health outcomes in infancy and childhood of moderate and late preterm infants. Semin Fetal Neonatal Med: 2012; 17 3 159 162
89. Vrijlandt E. JLE, Kerstjens J. M., Duiverman E. J., Bos A. F., Reijneveld S. A. Moderately preterm children have more respiratory problems during their first 5 years of life than children born full term. Am J Respir Crit Care Med: 2013; 187 11 1234 1240
90. Friedrich L., Pitrez P. M., Stein R. T., Goldani M., Tepper R., Jones M. H. Growth rate of lung function in healthy preterm infants. Am J Respir Crit Care Med: 2007; 176 12 1269 1273
91. Kotecha S. J., Dunstan F. D., Kotecha S. Long term respiratory outcomes of late preterm-born infants. Semin Fetal Neonatal Med: 2012; 17 2 77 81
92. Hoo A. F., Dezateux C., Henschen M., Costeloe K., Stocks J. Development of airway function in infancy after preterm delivery. J Pediatr: 2002; 141 5 652 658
93. Todisco T., de Benedictis F. M., Iannacci L., et al. Mild prematurity and respiratory functions. Eur J Pediatr: 1993; 152 1 55 58
94. DeMauro S. B., Patel P. R., Medoff-Cooper B., Posencheg M., Abbasi S. Postdischarge feeding patterns in early- and late-preterm infants. Clin Pediatr (Phila): 2011; 50 10 957 962
95. Petrou S., Khan K. Economic costs associated with moderate and late preterm birth: primary and secondary evidence. Semin Fetal Neonatal Med: 2012; 17 3 170 178