PH-sensitive micelles based on acid-labile pluronic F68-curcumin conjugates for improved tumor intracellular drug delivery

International Journal of Pharmaceutics

Volumn 502, Issue 1-2, 2016, Pages 28-37

  Fang, Xiao Bin ^a   Zhang, Jin Ming ^a   Xie, Xi ^b   Liu, Di ^c   He, Cheng Wei ^a   Wan, Jian Bo ^a   Chen, Mei Wan ^a  

^a University of Macau   (Macao)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cancer; Curcumin; pH sensitive; Pluronic F68; Polymer drug conjugate

Indexed keywords

ACID; ACID ANHYDRIDE; CURCUMIN; POLOXAMER; ANTINEOPLASTIC AGENT; MICELLE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; CANCER THERAPY; CAVEOLA; CELL PH; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENDOCYTOSIS; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; LIVER CANCER CELL LINE; MICELLE; MITOCHONDRIAL MEMBRANE POTENTIAL; OVARIAN CANCER CELL LINE; PARTICLE SIZE; PRIORITY JOURNAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; PH; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CURCUMIN; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICELLES; POLOXAMER;

EID: 84959017497     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.01.029     Document Type: Article

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