Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Waghela, Bhargav N ^a   Sharma, Anupama ^a   Dhumale, Suhashini ^a   Pandey, Shashibahl M ^b   Pathak, Chandramani ^a  

^a Indian Institute of Advanced Research   (India)

^b Smt CHM College   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYGLACTIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; COLON CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; DRUG UPTAKE; HUMAN; HUMAN CELL; IC50; MITOCHONDRIAL MEMBRANE POTENTIAL; PH; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SUSTAINED RELEASE FORMULATION; TRANSCRIPTION REGULATION; ANIMAL; BIOAVAILABILITY; CELL MOTION; CHEMISTRY; COLON TUMOR; DELAYED RELEASE FORMULATION; DRUG EFFECTS; METABOLISM; MOUSE; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

CURCUMA LONGA;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLONIC NEOPLASMS; CURCUMIN; DELAYED-ACTION PREPARATIONS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LACTIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; NF-KAPPA B; POLYGLYCOLIC ACID; REACTIVE OXYGEN SPECIES;

EID: 84923283329     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117526     Document Type: Article

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