Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy

Expert Opinion on Drug Delivery

Volumn 11, Issue 9, 2014, Pages 1367-1380

  Zhang, Jinming ^a   Li, Yingbo ^b   Gao, Wei ^b   Repka, Michael A ^c   Wang, Yitao ^a   Chen, Meiwan ^a  

^a China jack1987168 163com   (Macao)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Andrographolide; Breast cancer MAD MB 231 cells; Micelles; Pharmacokinetics; Poly (D,L lactide co glycolide) b poly (ethylene glycol) b poly (D,L lactide co glycolide) triblock copolymer

Indexed keywords

AMPHOPHILE; ANDROGRAPHOLIDE; COPOLYMER; POLY(LACTIDE CO GLYCOLIDE) B POLY(ETHYLENE GLYCOL) B POLY(LACTIDE CO GLYCOLIDE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; CANCER CELL LINE; CANCER THERAPY; CELL CYCLE ARREST; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG TUMOR LEVEL; ENCAPSULATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR TRANSPORT; M PHASE CELL CYCLE CHECKPOINT; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; RAT; SUSPENSION; ZETA POTENTIAL;

ANDROGRAPHOLIDE; BREAST CANCER MAD-MB-231 CELLS; MICELLES; PHARMACOKINETICS; POLY (D,L-LACTIDE-CO-GLYCOLIDE)-B-POLY (ETHYLENE GLYCOL)-B-POLY (D,L-LACTIDE-CO-GLYCOLIDE) TRIBLOCK COPOLYMER;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; DITERPENES; DRUG DELIVERY SYSTEMS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICELLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; POLYMERS; RATS; RATS, WISTAR;

EID: 84906324397     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2014.924503     Document Type: Article

References (34)

1. Jayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med 2013;2013:846740
2. Poolsup N, Suthisisang C, Prathanturarug S, et al. Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: Systematic review of randomized controlled trials. J Clin Pharm Ther 2004;29(1):37-45
3. Jarukamjorn K, Nemoto N. Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent andrographolide. J Health Sci 2008;54(4):370-81
4. Niranjan Reddy V, Malla Reddy S, Ravikanth V, et al. A new bis-Andrographolide ether from Andrographis paniculata nees and evaluation of anti-HIV activity. Nat Prod Res 2005;19(3):223-30
5. Sulaiman MR, Zakaria ZA, Rahman AA, et al. Antinociceptive and antiedematogenic activities of andrographolide isolated from Andrographis paniculata in animal models. Biol Res Nurs 2010;11(3):293-301
6. Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007;8(1):49-62
7. Lee YC, Lin HH, Hsu CH, et al. Inhibitory effects of andrographolide on migration and invasion in human nonsmall cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway. Eur J Pharmacol 2010;632(1):23-32
8. Hocker HJ, Cho KJ, Chen CY, et al. Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function. Proc Natl Acad Sci U S A 2013;110(25):10201-6
9. Chen M, Xie C, Liu L. Solubility of andrographolide in various solvents from (288.2 to 323.2) K. J Chem Eng Data 2010;55(11):5297-8
10. Jain PK, Khurana N, Pounikar Y, et al. Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-Andrographolide vesicular system. J Liposome Res 2013;23(2):110-18
11. Gelderblom H, Verweij J, Nooter K, et al. Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 2001;37(13):1590-8
12. Torchilin VP. Micellar nanocarriers: Pharmaceutical perspectives. Pharm Res 2007;24(1):1-16
13. Chen S, Pieper R, Webster DC, et al. Triblock copolymers: Synthesis, characterization, and delivery of a model protein. Int J Pharm 2005;288(2):207-18
14. Chen S, Singh J. Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation. Int J Pharm 2008;352(1):58-65
15. Gilani K, Moazeni E, Ramezanli T, et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. J Pharm Sci 2011;100(1):252-9
16. Liu J, Pang Y, Huang W, et al. Self-Assembly of phospholipid-Analogous hyperbranched polymers nanomicelles for drug delivery. Biomaterials 2010;31(6):1334-41
17. Wang S, Chen T, Chen R, et al. Emodin loaded solid lipid nanoparticles: Preparation, characterization and antitumor activity studies. Int J Pharm 2012;430(1-2):238-46
18. Aznar MA, Lasa Saracibar B, Estella Hermoso de Mendoza A, et al. Efficacy of edelfosine lipid nanoparticles in breast cancer cells. Int J Pharm 2013;454(2):720-6
19. Wong BM, Cordaro JG. Coumarin Dyes for dye-sensitized solar cells: A long-range-corrected density functional study. J Chem Phys 2008;129(21):214703
20. Yin Win K, Feng SS. Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials 2005;26(15):2713-22
21. Yang T, Sheng HH, Feng NP, et al. Preparation of andrographolide-loaded solid lipid nanoparticles and their in vitro and in vivo evaluations: Characteristics, release, absorption, transports, pharmacokinetics, and antihyperlipidemic activity. J Pharm Sci 2013;102(12):4414-25
22. Rathi RC, Zentner GM. Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties. US6004573; 1999
23. Chen S, Singh J. Controlled delivery of testosterone from smart polymer solution based systems: In vitro evaluation. Int J Pharm 2005;295(1-2):183-90
24. Pearton M, Allender C, Brain K, et al. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharm Res 2008;25(2):407-16
25. Song Z, Feng R, Sun M, et al. Curcumin-loaded PLGA-PEGPLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo. J Colloid Interface Sci 2011;354(1):116-23
26. Hans M, Lowman A. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci 2002;6(4):319-27
27. Satyanarayana C, Deevi DS, Rajagopalan R, et al. DRF 3188 a novel semi-synthetic analog of andrographolide: Cellular response to MCF 7 breast cancer cells. BMC Cancer 2004;4:26-1-8
28. Feng S-S, Mei L, Anitha P, et al. Poly (lactide)-vitamin E derivative/ montmorillonite nanoparticle formulations for the oral delivery of Docetaxel. Biomaterials 2009;30(19):3297-306
29. Conner SD, Schmid SL. Regulated portals of entry into the cell. Nature 2003;422(6):37-44
30. Treuel L, Jiang X, Nienhaus GU. New views on cellular uptake and trafficking of manufactured nanoparticles. J R Soc Interface 2013;10(82):1-7
31. Deng C, Jiang Y, Cheng R, et al. Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: Promises, progress and prospects. Nano Today 2012;7(5):467-80
32. Hu X, Jing X. Biodegradable amphiphilic polymer-drug conjugate micelles. Expert Opin Drug Deliv 2009;6(10):1079-90
33. Meng F, Hennink WE, Zhong Z. Reduction-sensitive polymers and bioconjugates for biomedical applications. Biomaterials 2009;30(12):2180-98
34. Sun H, Guo B, Li X, et al. Shell-sheddable micelles based on Dextran-SS-poly (caprolactone) diblock copolymer for efficient intracellular release of doxorubicin. Biomacromolecules 2010;11(4):848-54.