In Vitro and In Vivo Antitumor Activity of a Novel pH-Activated Polymeric Drug Delivery System for Doxorubicin

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Huan, Menglei ^a   Zhang, Bangle ^a   Teng, Zenghui ^a   Cui, Han ^a   Wang, Jieping ^b   Liu, Xinyou ^b   Xia, Hui ^c   Zhou, Siyuan ^a   Mei, Qibing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; MACROGOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; BREAST CARCINOMA; CANCER CELL CULTURE; CONTROLLED STUDY; COVALENT BOND; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG RELEASE; DRUG STRUCTURE; DRUG TARGETING; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PH; PROTON NUCLEAR MAGNETIC RESONANCE; SURVIVAL TIME; TREATMENT OUTCOME; TUMOR XENOGRAFT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MCF-7 CELLS; MICE; MICE, SCID; POLYETHYLENE GLYCOLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84866705003     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044116     Document Type: Article

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