The outer membrane porin OmpW of Acinetobacter baumannii is involved in iron uptake and colistin binding

FEBS Letters

Volumn 590, Issue 2, 2016, Pages 224-231

  Catel Ferreira, Manuella ^a   Marti, Sara ^a,b   Guillon, Laurent ^c   Jara, Luis ^d   Coadou, Gaël ^a   Molle, Virginie ^e   Bouffartigues, Emeline ^f   Bou, German ^g   Shalk, Isabelle ^c   Jouenne, Thierry ^a   Vila Farrés, Xavier ^b   Dé, Emmanuelle ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e UNIVERSITÉ DE MONTPELLIER   (France)

^f UNIVERSITÉ DE ROUEN   (France)

^g HOSPITAL JUAN CANALEJO   (Spain)

Author keywords

colistin resistance; hydrophobic channel; iron homeostasis

Indexed keywords

COLISTIN; IMIPENEM; IRON 55; LIPID; OUTER MEMBRANE PROTEIN W; PORIN; UNCLASSIFIED DRUG; IRON; OUTER MEMBRANE PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; HOMEOSTASIS; IN VIVO STUDY; IRON TRANSPORT; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; AMINO ACID SEQUENCE; CHEMISTRY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

ACINETOBACTER BAUMANNII; AMINO ACID SEQUENCE; BACTERIAL OUTER MEMBRANE PROTEINS; COLISTIN; IRON; MOLECULAR SEQUENCE DATA; PORINS; PROTEIN BINDING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84959010644     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1002/1873-3468.12050     Document Type: Article

References (41)

1. Dijkshoorn L, Nemec A, and, Seifert H, (2007) An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol 5, 939-951.
2. Peleg AY, Seifert H, and, Paterson DL, (2008) Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 21, 538-582.
3. Vila J, Marti S, and, Sanchez-Cespedes J, (2007) Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii. J Antimicrob Chemother 59, 1210-1215.
4. Vila J, and, Pachon J, (2008) Therapeutic options for Acinetobacter baumannii infections. Expert Opin Pharmacother 9, 587-599.
5. Ko KS, Suh JY, Kwon KT, Jung SI, Park KH, Kang CI, Chung DR, and, Peck KR, (2007) High rates of resistance to colistin and polymyxin B in subgroups of Acinetobacter baumannii isolates from Korea. J Antimicrob Chemother 60, 1163-1167.
6. Henry R, Vithanage N, Harrison P, Seemann T, Coutts S, Moffatt JH, Nation RL, Li J, Harper M, Adler B, et al,. (2011) Colistin-resistant, lipopolysaccharide-deficient Acinetobacter baumannii responds to lipopolysaccharide loss through increased expression of genes involved in the synthesis and transport of lipoproteins, phospholipids and poly-β-1,6-N-acetylglucosamine. Antimicrob Agents Chemother 56, 59-69.
7. Lopez-Rojas R, Jimenez-Mejias ME, Lepe JA, and, Pachõn J, (2011) Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: a case report from Spain. J Infect Dis 204, 1147-1148.
8. Cai Y, Chai D, Wang R, Liang B, and, Bai N, (2012) Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies. J Antimicrob Chemother 67, 1607-1615.
9. Siroy A, Cosette P, Seyer D, Lemaître-Guillier C, Vallenet D, Van Dorsselaer A, Boyer-Mariotte S, Jouenne T, and, Dé E, (2006) Global comparison of the membrane subproteomes between a multidrug-resistant Acinetobacter baumannii strain and a reference strain. J Proteome Res 5, 3385-3398.
10. Fernandez-Reyes M, Rodriguez-Falcon M, Chiva C, Pachõn J, Andreu D, and, Rivas L, (2009) The cost of resistance to colistin in Acinetobacter baumannii: a proteomic perspective. Proteomics 9, 1632-1645.
11. Yun S, Choi C, Kwon S, Park G, Cho K, Kwon K, Kim JY, Yoo JS, Lee JC, Choi JS, et al,. (2011) Quantitative proteomic analysis of cell wall and plasma membrane fractions from multidrug-resistant Acinetobacter baumannii. J Proteome Res 10, 459-469.
12. Vashist J, Tiwari V, Kapil A, and, Rajeswari MR, (2010) Quantitative profiling and identification of outer membrane proteins of betalactam resistant strain of Acinetobacter baumannii. J Proteome Res 9, 1121-1128.
13. Chopra S, Ramkissoon K, and, Anderson DC, (2013) A systematic quantitative proteomic examination of multidrug resistance in Acinetobacter baumannii. J Proteomics 84, 17-39.
14. Hong H, Patel DR, Tamm LK, and, van den Berg B, (2006) The outer membrane protein OmpW forms an eight-stranded beta-barrel with a hydrophobic channel. J Biol Chem 281, 7568-7577.
15. McPhee JB, Tamber S, Bains M, Maier E, Gellatly S, Lo A, Benz R, and, Hancock RE, (2009) The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel. FEMS Microbiol Lett 296, 241-247.
16. Touw DS, Patel DR, and, van den Berg B, (2010) The crystal structure of OprG from Pseudomonas aeruginosa, a potential channel for transport of hydrophobic molecules across the outer membrane. PLoS One 5, e15016.
17. Brambilla L, Morán-Barrio J, and, Viale AM, (2014) Expression of the Escherichia coli ompW colicin S4 receptor gene is regulated by temperature and modulated by the H-NS and StpA nucleoid-associated proteins. FEMS Microbiol Lett 352, 238-244.
18. Wu L, Lin X, Wang F, Ye D, Xiao X, Wang S, and, Peng X, (2006) OmpW and OmpV are required for NaCl regulation in Photobacterium damsela. J Proteome Res 5, 2250-2257.
19. Wu L, Lin XM, and, Peng XX, (2009) From proteome to genome for functional characterization of pH-dependent outer membrane proteins in Escherichia coli. J Proteome Res 8, 1059-1070.
20. McHugh JP, Rodriguez-Quinones F, Abdul-Tehrani H, Svistunenko DA, Poole RK, Cooper CE, and, Andrews SC, (2003) Global iron-dependent gene regulation in Escherichia coli. A new mechanism for iron homeostasis. J Biol Chem 278, 29478-29486.
21. Xu C, Lin X, Ren H, Zhang Y, Wang S, and, Peng X, (2006) Analysis of outer membrane proteome of Escherichia coli related to resistance to ampicillin and tetracycline. Proteomics 6, 462-473.
22. Li H, Lin XM, Wang SY, and, Peng XX, (2007) Identification and antibody-therapeutic targeting of chloramphenicol-resistant outer membrane proteins in Escherichia coli. J Proteome Res 6, 3628-3636.
23. Li H, Wang BC, Xu WJ, Lin XM, and, Peng XX, (2008) Identification and network of outer membrane proteins regulating streptomysin resistance in Escherichia coli. J Proteome Res 7, 4040-4049.
24. Lin XM, Wu LN, Li H, Wang SY, and, Peng XX, (2008) Downregulation of Tsx and OmpW and upregulation of OmpX are required for iron homeostasis in Escherichia coli. J Proteome Res 7, 1235-1243.
25. Lin XM, Yang JN, Peng XX, and, Li H, (2010) A novel negative regulation mechanism of bacterial outer membrane proteins in response to antibiotic resistance. J Proteome Res 9, 5952-5959.
26. Zhang DF, Jiang B, Xiang ZM, &, Wang SY, (2008) Functional characterization of altered outer membrane proteins for tetracycline resistance in Escherichia coli. Int J Antimicrob Agents, 32, 315-319.
27. Nwugo CC, Gaddy JA, Zimbler DL, and, Actis LA, (2010) Deciphering the iron response in Acinetobacter baumannii: a proteomics approach. J Proteomics 74, 44-58.
28. Tiwari V, Vashistt J, Kapil A, and, Moganty R, (2012) Comparative proteomics of inner membrane fraction from carbapenem-resistant Acinetobacter baumannii with a reference strain. PLoS One 7, e39451.
29. Yun SH, Choi CW, Park SH, Lee JC, Leem SH, Choi JS, Kim S, and, Kim SI, (2008) Proteomic analysis of outer membrane proteins from Acinetobacter baumannii DU202 in tetracycline stress condition. J Microbiol 46, 720-727.
30. Siroy A, Molle V, Lemaitre-Guillier C, Vallenet D, Pestel-Caron M, Cozzone AJ, Jouenne T, and, Dé E, (2005) Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. Antimicrob Agents Chemother 49, 4876-4883.
31. Catel-Ferreira M, Coadou G, Molle V, Mugnier Nordman P, Siroy A, Jouenne T, and, Dé E, (2011) Structure-function relationships of CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. J Antimicrob Chemother 66, 2053-2056.
32. Aranda J, Poza M, Pardo BG, Rumbo C, Parreira JR, Rodríguez-Velo P, and, Bou G, (2010) A rapid and simple method for constructing stable mutants of Acinetobacter baumannii. BMC Microbiol 10, 279.
33. Hancock RE, and, Carey AM, (1979) Outer membrane of Pseudomonas aeruginosa: heat- 2-mercaptoethanol-modifiable proteins. J Bacteriol 140, 902-910.
34. Dupont M, De E, Chollet R, Chevalier J, and, Pagès JM, (2004) Enterobacter aerogenes OmpX, a cation-selective channel mar- and osmo-regulated. FEBS Lett 569, 27-30.
35. Sugawara E, and, Nikaido H, (2012) OmpA is the principal nonspecific slow porin of Acinetobacter baumannii. J Bacteriol 194, 4089-4096.
36. Huang H, and, Hancock RE, (1996) The role of specific surface loop regions in determining the function of the imipenem-specific pore protein OprD of Pseudomonas aeruginosa. J Bacteriol 178, 3085-3090.
37. Van Gelder P, Dumas F, and, Winterhalter M, (2000) Understanding the function of bacterial outer membrane channels by reconstitution into black lipid membranes. Biophys Chem 85, 153-167.
38. Vaara M, and, Vaara T, (2010) Structure-activity studies on novel polymyxin derivatives that carry only three positive charges. Peptides 31, 2318-2321.
39. Vaara M, (2013) Novel derivatives of polymyxins. J Antimicrob Chemother 68, 1213-1219.
40. Vaara M, and, Vaara T, (1983) Sensitization of Gram-negative bacteria to antibiotics and complement by nontoxic oligopeptides. Nature 303, 526-528.
41. Olaitan AO, Morand S, and, Rolain J-M, (2014) Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria. Front Microbiol 5, 643.