Quantitative proteomic analysis of cell wall and plasma membrane fractions from multidrug-resistant acinetobacter baumannii

Journal of Proteome Research

Volumn 10, Issue 2, 2011, Pages 459-469

  Yun, Sung Ho ^a   Choi, Chi Won ^a   Kwon, Sang Oh ^a,c   Park, Gun Wook ^a,c   Cho, Kun ^a   Kwon, Kyung Hoon ^a   Kim, Jin Young ^a   Yoo, Jong Shin ^a,c   Lee, Je Chul ^b   Choi, Jong Soon ^a,c   Kim, Soohyun ^a   Kim, Seung Il ^a  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

1 DE LC MS MS; Acinetobacter baumannii; iTRAQ; Membrane protein; Multidrug resistant

Indexed keywords

BACTERIAL PROTEIN; BETA LACTAMASE; IMIPENEM; PENICILLIN BINDING PROTEIN; PROTEIN KINASE; RIBOSOME PROTEIN; TETRACYCLINE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL WALL; BACTERIAL MEMBRANE; BACTERIAL OUTER MEMBRANE; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL DIVISION; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; GEL ELECTROPHORESIS; IRON TRANSPORT; LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NODULATION; NONHUMAN; ONE DIMENSIONAL ELECTROPHORESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; CELL MEMBRANE; CELL WALL; CHROMATOGRAPHY, LIQUID; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; IMIPENEM; ISOTOPE LABELING; MEMBRANE TRANSPORT PROTEINS; PROTEOME; PROTEOMICS; TANDEM MASS SPECTROMETRY; TETRACYCLINE; TETRACYCLINE RESISTANCE;

ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 79955378367     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr101012s     Document Type: Article

References (40)

1. Peleg, A. Y.; Seifert, H.; Paterson, D. L. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol Rev. 2008, 21 (3), 538-82.
2. Bergogne-Berezin, E.; Towner, K. J. Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin. Microbiol. Rev. 1996, 9 (2), 148-65. (Pubitemid 26123943)
3. Abbo, A.; Navon-Venezia, S.; Hammer-Muntz, O.; Krichali, T.; Siegman-Igra, Y.; Carmeli, Y. Multidrug-resistant Acinetobacter baumannii. Emerging Infect. Dis. 2005, 11 (1), 22-9. (Pubitemid 40093348)
4. Dijkshoorn, L.; Nemec, A.; Seifert, H. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat. Rev. Microbiol. 2007, 5 (12), 939-51. (Pubitemid 350131182)
5. Poirel, L.; Marque, S.; Heritier, C.; Segonds, C.; Chabanon, G.; Nordmann, P. OXA-58, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2005, 49 (1), 202-8. (Pubitemid 40065794)
6. Seward, R. J.; Lambert, T.; Towner, K. J. Molecular epidemiology of aminoglycoside resistance in Acinetobacter spp. J. Med. Microbiol. 1998, 47 (5), 455-62. (Pubitemid 28191050)
7. Vila, J.; Ruiz, J.; Goni, P.; Jimenez de Anta, T. Quinolone-resistance mutations in the topoisomerase IV parC gene of Acinetobacter baumannii. J. Antimicrob. Chemother. 1997, 39 (6), 757-62. (Pubitemid 27296416)
8. Ruzin, A.; Keeney, D.; Bradford, P. A. AdeABC multidrug efflux pump is associated with decreased susceptibility to tigecycline in Acinetobacter calcoaceticus-Acinetobacter baumannii complex. J Antimicrob. Chemother. 2007, 59 (5), 1001-4. (Pubitemid 47073374)
9. del Mar Tomas, M.; Beceiro, A.; Perez, A.; Velasco, D.; Moure, R.; Villanueva, R.; Martinez-Beltran, J.; Bou, G. Cloning and functional analysis of the gene encoding the 33- to 36-kilodalton outer membrane protein associated with carbapenem resistance in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2005, 49 (12), 5172-5. (Pubitemid 41778945)
10. Limansky, A. S.; Mussi, M. A.; Viale, A. M. Loss of a 29-kilodalton outer membrane protein in Acinetobacter baumannii is associated with imipenem resistance. J. Clin. Microbiol. 2002, 40 (12), 4776-8. (Pubitemid 35434989)
11. Dupont, M.; Pages, J. M.; Lafitte, D.; Siroy, A.; Bollet, C. Identification of an OprD homologue in Acinetobacter baumannii. J. Proteome Res. 2005, 4 (6), 2386-90. (Pubitemid 41814312)
12. Magnet, S.; Courvalin, P.; Lambert, T. Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454. Antimicrob. Agents Chemother. 2001, 45 (12), 3375-80. (Pubitemid 33107849)
13. Mussi, M. A.; Limansky, A. S.; Viale, A. M. Acquisition of resistance to carbapenems in multidrug-resistant clinical strains of Acine-tobacter baumannii: natural insertional inactivation of a gene encoding a member of a novel family of beta-barrel outer membrane proteins. Antimicrob. Agents Chemother. 2005, 49 (4), 1432-40. (Pubitemid 40463373)
14. Siroy, A.; Cosette, P.; Seyer, D.; Lemaitre-Guillier, C; Vallenet, D.; Van Dorsselaer, A.; Boyer-Mariotte, S.; Jouenne, T.; De, E. Global comparison of the membrane subproteomes between a multidrug- resistant Acinetobacter baumannii strain and a reference strain. J Proteome Res. 2006, 5 (12), 3385-98. (Pubitemid 44904330)
15. Marti, S.; Sanchez-Cespedes, J.; Oliveira, E.; Bellido, D.; Giralt, E.; Vila, J. Proteomic analysis of a fraction enriched in cell envelope proteins of Acinetobacter baumannii. Proteomics 2006, 6 (1), S82- 7.
16. Vashist, J.; Tiwari, V.; Kapil, A.; Rajeswari, M. R. Quantitative profiling and identification of outer membrane proteins of beta- lactam resistant strain of Acinetobacter baumannii. J. Proteome Res. 2010, 9 (2), 1121-8.
17. Vallenet, D.; Nordmann, P.; Barbe, V.; Poirel, L.; Mangenot, S.; Bataille, E.; Dossat, C.; Gas, S.; Kreimeyer, A.; Lenoble, P.; Oztas, S.; Poulain, J.; Segurens, B.; Robert, C.; Abergel, C.; Claverie, J. M.; Raoult, D.; Medigue, C.; Weissenbach, J.; Cruveiller, S. Comparative analysis of Acinetobacters: three genomes for three lifestyles. PLoS One 2008, 3 (3), e1805.
18. Smith, M. G.; Gianoulis, T. A.; Pukatzki, S.; Mekalanos, J. J.; Ornston, L. N.; Gerstein, M.; Snyder, M. New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis. Genes Dev. 2007, 21 (5), 601-14. (Pubitemid 46409474)
19. Fernandez-Reyes, M.; Rodriguez-Falcon, M.; Chiva, C.; Pachon, J.; Andreu, D.; Rivas, L. The cost of resistance to colistin in Acine-tobacter baumannii: a proteomic perspective. Proteomics 2009, 9 (6), 1632-45.
20. Soares, N. C.; Cabral, M. P.; Gayoso, C.; Mallo, S.; Rodriguez-Velo, P.; Fernandez-Moreira, E.; Bou, G. Associating growth-phase-related changes in the proteome of Acinetobacter baumannii with increased resistance to oxidative stress. J. Proteome Res. 2010, 9 (4), 1951-64.
21. Soares, N. C.; Cabral, M. P.; Parreira, J. R.; Gayoso, C.; Barba, M. J.; Bou, G. 2-DE analysis indicates that Acinetobacter baumannii displays a robust and versatile metabolism. Proteome Sci. 2009, 7, 37.
22. Park, S. H.; Kim, J. W.; Yun, S. H.; Leem, S. H.; Kahng, H. Y.; Kim, S. I. Characterization of beta-ketoadipate pathway from multi-drug resistance bacterium, Acinetobacter baumannii DU202 by proteomic approach. J. Microbiol. 2006, 44 (6), 632-40.
23. Yun, S. H.; Choi, C. W.; Park, S. H.; Lee, J. C.; Leem, S. H.; Choi, J. S.; Kim, S.; Kim, S. I. Proteomic analysis of outer membrane proteins from Acinetobacter baumannii DU202 in tetracycline stress condition. J. Microbiol. 2008, 46 (6), 720-7.
24. Kwon, S. O.; Gho, Y. S.; Lee, J. C.; Kim, S. I. Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. FEMS Microbiol. Lett. 2009, 297 (2), 150-6.
25. Karageorgopoulos, D. E.; Falagas, M. E. Current control and treatment of multidrug-resistant Acinetobacter baumannii infections. Lancet Infect. Dis. 2008, 8 (12), 751-62.
26. Vila, J.; Pachon, J. Therapeutic options for Acinetobacter baumannii infections. Expert Opin. Pharmacother. 2008, 9 (4), 587-99. (Pubitemid 351425386)
27. Gordon, N. C.; Wareham, D. W. A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline. J. Antimicrob. Chemother. 2009, 63 (4), 775-80.
28. Molloy, M. P.; Herbert, B. R.; Slade, M. B.; Rabilloud, T.; Nouwens, A. S.; Williams, K. L.; Gooley, A. A. Proteomic analysis of the Escherichia coli outer membrane. Eur. J. Biochem. 2000, 267 (10), 2871-81. (Pubitemid 30321332)
29. Krieg, R. C.; Dong, Y.; Schwamborn, K.; Knuechel, R. Protein quantification and its tolerance for different interfering reagents using the BCA-method with regard to 2D SDS PAGE. J. Biochem. Biophys. Methods 2005, 65 (1), 13-9. (Pubitemid 41562866)
30. Xu, C.; Lin, X.; Ren, H.; Zhang, Y.; Wang, S.; Peng, X. Analysis of outer membrane proteome of Escherichia coli related to resistance to ampicillin and tetracycline. Proteomics 2006, 6 (2), 462-73. (Pubitemid 43208026)
31. Kim, Y. H.; Cho, K.; Yun, S. H.; Kim, J. Y.; Kwon, K. H.; Yoo, J. S.; Kim, S. I. Analysis of aromatic catabolic pathways in Pseudomonas putida KT 2440 using a combined proteomic approach: 2-DE/MS and cleavable isotope-coded affinity tag analysis. Proteomics 2006, 6 (4), 1301-18.
32. Yu, C. S.; Chen, Y. C.; Lu, C. H.; Hwang, J. K. Prediction of protein subcellular localization. Proteins 2006, 64 (3), 643-51.
33. Moller, S.; Croning, M. D.; Apweiler, R. Evaluation of methods for the prediction of membrane spanning regions. Bioinformatics 2001, 17 (7), 646-53. (Pubitemid 32707587)
34. Ishihama, Y.; Oda, Y.; Tabata, T.; Sato, T.; Nagasu, T.; Rappsilber, J.; Mann, M. Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein. Mol. Cell. Proteomics 2005, 4 (9), 1265-72. (Pubitemid 41448714)
35. Nemec, A.; Maixnerova, M.; van der Reijden, T. J.; van den Broek, P. J.; Dijkshoorn, L. Relationship between the AdeABC efflux system gene content, netilmicin susceptibility and multidrug resistance in a genotypically diverse collection of Acinetobacter baumannii strains. J. Antimicrob. Chemother. 2007, 60 (3), 483-9. (Pubitemid 47299860)
36. Damier-Piolle, L.; Magnet, S.; Bremont, S.; Lambert, T.; Courvalin, P. AdelJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2008, 52 (2), 557-62. (Pubitemid 351170828)
37. Peng, X.; Xu, C.; Ren, H.; Lin, X.; Wu, L.; Wang, S. Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Pseudomonas aeruginosa responding to ampicilin, kanamycin, and tetracycline resistance. J. Proteome Res. 2005, 4 (6), 2257-65. (Pubitemid 41814295)
38. Tomaras, A. P.; Flagler, M. J.; Dorsey, C. W.; Gaddy, J. A.; Actis, L. A. Characterization of a two-component regulatory system from Acinetobacter baumannii that controls biofilm formation and cellular morphology. Microbiology 2008, 154 (Pt. 11), 3398-409.
39. Zeng, X.; Xu, F.; Lin, J. Molecular, antigenic, and functional characteristics of ferric enterobactin receptor CfrA in Campylo-bacter jejuni. Infect. Immun. 2009, 77 (12), 5437-48.
40. Peleg, A. Y.; Adams, J.; Paterson, D. L. Tigecycline efflux as a mechanism for nonsusceptibility in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2007, 51 (6), 2065-9. (Pubitemid 46903095)