Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms

Journal of Vascular Surgery

Volumn 51, Issue 4, 2010, Pages 1015-1025

  Kwee, Robert M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERY CALCIFICATION; ATHEROSCLEROTIC PLAQUE; BRAIN ISCHEMIA; CAROTID PLAQUE CALCIFICATION; DISEASE ASSOCIATION; HUMAN; MEASUREMENT; PRIORITY JOURNAL; REVIEW; STROKE; SYSTEMATIC REVIEW;

BRAIN ISCHEMIA; CALCINOSIS; CAROTID STENOSIS; DISEASE PROGRESSION; EVIDENCE-BASED MEDICINE; HUMANS; ODDS RATIO; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 77949914720     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2009.08.072     Document Type: Review

References (65)

1. Chaturvedi S., Bruno A., Feasby T., Holloway R., Benavente O., Cohen S.N., et al. Carotid endarterectomy-an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 65 (2005) 794-801
2. Naghavi M., Libby P., Falk E., Casscells S.W., Litovsky S., Rumberger J., et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 108 (2003) 1664-1672
3. Golledge J., Greenhalgh R.M., and Davies A.H. The symptomatic carotid plaque. Stroke 31 (2000) 774-781
4. Slevin M., Wang Q., Font M.A., Luque A., Juan-Babot O., Gaffney J., et al. Atherothrombosis and plaque heterology: different location or a unique disease?. Pathobiology 75 (2008) 209-225
5. Huang H., Virmani R., Younis H., Burke A.P., Kamm R.D., and Lee R.T. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation 103 (2001) 1051-1056
6. Nandalur K.R., Baskurt E., Hagspiel K.D., Finch M., Phillips C.D., Bollampally S.R., and Kramer C.M. Carotid artery calcification on CT may independently predict stroke risk. AJR Am J Roentgenol 186 (2006) 547-552
7. Polak J.F., Shemanski L., O'Leary D.H., Lefkowitz D., Price T.R., Savage P.J., et al. Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study. Radiology 208 (1998) 649-654
8. Halliday A., Mansfield A., Marro J., Peto C., Peto R., Potter J., et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet 363 (2004) 1491-1502
9. Tegos T.J., Sohail M., Sabetai M.M., Robless P., Akbar N., Pare G., et al. Echomorphologic and histopathologic characteristics of unstable carotid plaques. AJNR Am J Neuroradiol 21 (2000) 1937-1944
10. Denzel C., Lell M., Maak M., Höckl M., Balzer K., Müller K.M., et al. Carotid artery calcium: accuracy of a calcium score by computed tomography-an in vitro study with comparison to sonography and histology. Eur J Vasc Endovasc Surg 28 (2004) 214-220
11. Higgins C.L., Marvel S.A., and Morrisett J.D. Quantification of calcification in atherosclerotic lesions. Arterioscler Thromb Vasc Biol 25 (2005) 1567-1576
12. Wintermark M., Jawadi S.S., Rapp J.H., Tihan T., Tong E., Glidden D.V., et al. High-resolution CT imaging of carotid artery atherosclerotic plaques. AJNR Am J Neuroradiol 29 (2008) 875-882
13. Saam T., Ferguson M.S., Yarnykh V.L., Takaya N., Xu D., Polissar N.L., et al. Quantitative evaluation of carotid plaque composition by in vivo MRI. Arterioscler Thromb Vasc Biol 25 (2005) 234-239
14. Lal B.K., Hobson II R.W., Pappas P.J., Kubicka R., Hameed M., Chakhtoura E.Y., et al. Pixel distribution analysis of B-mode ultrasound scan images predicts histologic features of atherosclerotic carotid plaques. J Vasc Surg 35 (2002) 1210-1217
15. Altman D.G., and Bland J.M. Standard deviations and standard errors. BMJ 331 (2005) 903
16. Cochrane Collaboration open learning material for reviewers, version 1.1, November 2002. http://www.cochrane-net.org/openlearning/ Accessed May 4, 2009
17. Glass G.V. Primary, secondary, and meta-analysis of research. Educational Researcher 5 (1976) 3-8
18. Bland J.M., and Altman D.G. Statistics notes. The odds ratio. BMJ 320 (2000) 1468
19. Lewis S., and Clarke M. Forest plots: trying to see the wood and the trees. BMJ 322 (2001) 1479-1480
20. Higgins J.P., Thompson S.G., Deeks J.J., and Altman D.G. Measuring inconsistency in meta-analyses. BMJ 327 (2003) 557-560
21. Egger M., Davey Smith G., Schneider M., and Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 315 (1997) 629-634
22. Lau J., Ioannidis J.P., Terrin N., Schmid C.H., and Olkin I. The case of the misleading funnel plot. BMJ 333 (2006) 597-600
23. Verhoeven B., Hellings W.E., Moll F.L., de Vries J.P., de Kleijn D.P., de Bruin P., et al. Carotid atherosclerotic plaques in patients with transient ischemic attacks and stroke have unstable characteristics compared with plaques in asymptomatic and amaurosis fugax patients. J Vasc Surg 42 (2005) 1075-1081
24. Hatsukami T.S., Ferguson M.S., Beach K.W., Gordon D., Detmer P., Burns D., et al. Carotid plaque morphology and clinical events. Stroke 28 (1997) 95-100
25. Kardoulas D.G., Katsamouris A.N., Gallis P.T., Philippides T.P., Anagnostakos N.K., Gorgoyannis D.S., and Gourtsoyannis N.C. Ultrasonographic and histologic characteristics of symptom-free and symptomatic carotid plaque. Cardiovasc Surg 4 (1996) 580-590
26. [No authors listed]. European Carotid Plaque Study Group. Carotid artery plaque composition-relationship to clinical presentation and ultrasound B-mode imaging. Eur J Vasc Endovasc Surg 10 (1995) 23-30
27. Culebras A., Otero C., Toledo J.R., and Rubin B.S. Computed tomographic study of cervical carotid calcification. Stroke 20 (1989) 1472-1476
28. Hunt J.L., Fairman R., Mitchell M.E., Carpenter J.P., Golden M., Khalapyan T., et al. Bone formation in carotid plaques: a clinicopathological study. Stroke 33 (2002) 1214-1219
29. Hellings W.E., Pasterkamp G., Verhoeven B.A., De Kleijn D.P., De Vries J.P., Seldenrijk K.A., et al. Gender-associated differences in plaque phenotype of patients undergoing carotid endarterectomy. J Vasc Surg 45 (2007) 289-296 discussion 296-7
30. van Oostrom O., Velema E., Schoneveld A.H., de Vries J.P., de Bruin P., Seldenrijk C.A., et al. Age-related changes in plaque composition: a study in patients suffering from carotid artery stenosis. Cardiovasc Pathol 14 (2005) 126-134
31. Gonçalves I., Lindholm M.W., Pedro L.M., Dias N., Fernandes e Fernandes J., Fredrikson G.N., et al. Elastin and calcium rather than collagen or lipid content are associated with echogenicity of human carotid plaques. Stroke 35 (2004) 2795-2800
32. Katano H., and Yamada K. Analysis of calcium in carotid plaques with Agatston scores for appropriate selection of surgical intervention. Stroke 38 (2007) 3040-3044
33. Baroncini L.A., Filho A.P., Ramos S.G., Martins A.R., and Murta Jr. L.O. Histological composition and progression of carotid plaque. Thromb J 5 (2007) 4
34. Seeger J.M., and Klingman N. The relationship between carotid plaque composition and neurologic symptoms. J Surg Res 43 (1987) 78-85
35. Agapitos E., Kavantzas N., Bakouris M., Pavlopoulos P.M., Kassis K., Liapis C., et al. Estimation of the percentage of carotid atheromatous plaque components and investigation of a probable correlation with the neurologic status of the patients. Gen Diagn Pathol 142 (1996) 105-108
36. Serfaty J.M., Nonent M., Nighoghossian N., Rouhart F., Derex L., Rotaru C., et al. Plaque density on CT, a potential marker of ischemic stroke. Neurology 66 (2006) 118-120
37. Romero J.M., Babiarz L.S., Forero N.P., Murphy E.K., Schaefer P.W., Gonzalez R.G., and Lev M.H. Arterial wall enhancement overlying carotid plaque on CT angiography correlates with symptoms in patients with high grade stenosis. Stroke 40 (2009) 1894-1896
38. Peeters W., Hellings W.E., de Kleijn D.P., de Vries J.P., Moll F.L., Vink A., and Pasterkamp G. Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization. Arterioscler Thromb Vasc Biol 29 (2009) 128-133
39. Wahlgren C.M., Zheng W., Shaalan W., Tang J., and Bassiouny H.S. Human carotid plaque calcification and vulnerability. Relationship between degree of plaque calcification, fibrous cap inflammatory gene expression and symptomatology. Cerebrovasc Dis 27 (2009) 193-200
40. Wintermark M., Arora S., Tong E., Vittinghoff E., Lau B.C., Chien J.D., et al. Carotid plaque computed tomography imaging in stroke and nonstroke patients. Ann Neurol 64 (2008) 149-157
41. Raman S.V., Winner III M.W., Tran T., Velayutham M., Simonetti O.P., Baker P.B., et al. In vivo atherosclerotic plaque characterization using magnetic susceptibility distinguishes symptom-producing plaques. JACC Cardiovasc Imaging 1 (2008) 49-57
42. Nandalur K.R., Hardie A.D., Raghavan P., Schipper M.J., Baskurt E., and Kramer C.M. Composition of the stable carotid plaque: insights from a multidetector computed tomography study of plaque volume. Stroke 38 (2007) 935-940
43. Uwatoko T., Toyoda K., Inoue T., Yasumori K., Hirai Y., Makihara N., et al. Carotid artery calcification on multislice detector-row computed tomography. Cerebrovasc Dis 24 (2007) 20-26
44. Miralles M., Merino J., Busto M., Perich X., Barranco C., and Vidal-Barraquer F. Quantification and characterization of carotid calcium with multi-detector CT-angiography. Eur J Vasc Endovasc Surg 32 (2006) 561-567
45. Baroncini L.A., Pazin Filho A., Murta Junior L.O., Martins A.R., Ramos S.G., Cherri J., and Piccinato C.E. Ultrasonic tissue characterization of vulnerable carotid plaque: correlation between videodensitometric method and histological examination. Cardiovasc Ultrasound 4 (2006) 32
46. Saam T., Cai J., Ma L., Cai Y.Q., Ferguson M.S., Polissar N.L., et al. Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. Radiology 240 (2006) 464-472
47. Lal B.K., Hobson II R.W., Hameed M., Pappas P.J., Padberg Jr. F.T., Jamil Z., and Durán W.N. Noninvasive identification of the unstable carotid plaque. Ann Vasc Surg 20 (2006) 167-174
48. Fisher M., Paganini-Hill A., Martin A., Cosgrove M., Toole J.F., Barnett H.J., and Norris J. Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke 36 (2005) 253-257
49. Nandalur K.R., Baskurt E., Hagspiel K.D., Phillips C.D., and Kramer C.M. Calcified carotid atherosclerotic plaque is associated less with ischemic symptoms than is noncalcified plaque on MDCT. AJR Am J Roentgenol 184 (2005) 295-298
50. Shaalan W.E., Cheng H., Gewertz B., McKinsey J.F., Schwartz L.B., Katz D., et al. Degree of carotid plaque calcification in relation to symptomatic outcome and plaque inflammation. J Vasc Surg 40 (2004) 262-269
51. Gonçalves I., Moses J., Dias N., Pedro L.M., Fernandes e Fernandes J., Nilsson J., and Ares M.P. Changes related to age and cerebrovascular symptoms in the extracellular matrix of human carotid plaques. Stroke 34 (2003) 616-622
52. Kim D.I., Lee S.J., Lee B.B., Kim Y.I., Chung C.S., Seo D.W., et al. The relationship between the angiographic findings and the clinical features of carotid artery plaque. Surg Today 30 (2000) 37-42
53. Montauban van Swijndregt A.D., Elbers H.R., Moll F.L., de Letter J., and Ackerstaff R.G. Cerebral ischemic disease and morphometric analyses of carotid plaques. Ann Vasc Surg 13 (1999) 468-474
54. Carr S., Farb A., Pearce W.H., Virmani R., and Yao J.S. Atherosclerotic plaque rupture in symptomatic carotid artery stenosis. J Vasc Surg 23 (1996) 755-765 discussion 765-6
55. Seeger J.M., Barratt E., Lawson G.A., and Klingman N. The relationship between carotid plaque composition, plaque morphology, and neurologic symptoms. J Surg Res 58 (1995) 330-336
56. Avril G., Batt M., Guidoin R., Marois M., Hassen-Khodja R., Daune B., et al. Carotid endarterectomy plaques: correlations of clinical and anatomic findings. Ann Vasc Surg 5 (1991) 50-54
57. Bassiouny H.S., Davis H., Massawa N., Gewertz B.L., Glagov S., and Zarins C.K. Critical carotid stenoses: morphologic and chemical similarity between symptomatic and asymptomatic plaques. J Vasc Surg 9 (1989) 202-212
58. [No authors listed] North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress. Stroke 22 (1991) 711-720
59. [No authors listed]. MRC European Carotid Surgery Trial. interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group. Lancet 337 (1991) 1235-1243
60. de Jong G., Kessels F., and Lodder J. Two types of lacunar infarcts: further arguments from a study on prognosis. Stroke 33 (2002) 2072-2076
61. Rothwell P.M., Mayberg M.R., Warlow C.P., Barnett H.J., and Carotid Endarterectomy Trialists' Collaboration. Meta-analysis of individual patient data from randomised controlled trials of carotid endarterectomy for symptomatic stenosis: the efficacy of carotid surgery in important pre-defined subgroups. Cerebrovasc Dis 10 Suppl 2 (2000) 8
62. Kakkos S.K., Sabetai M., Tegos T., Stevens J., Thomas D., Griffin M., et al. Silent embolic infarcts on computed tomography brain scans and risk of ipsilateral hemispheric events in patients with asymptomatic internal carotid artery stenosis. J Vasc Surg 49 (2009) 902-909
63. Abedin M., Tintut Y., and Demer L.L. Vascular calcification: mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol 24 (2004) 1161-1170
64. [No authors listed] Study design for randomized prospective trial of carotid endarterectomy for asymptomatic atherosclerosis. The Asymptomatic Carotid Atherosclerosis Study Group. Stroke 20 (1989) 844-849
65. Li Z.Y., Howarth S., Tang T., Graves M., U-King-Im J., and Gillard J.H. Does calcium deposition play a role in the stability of atheroma?. Location may be the key. Cerebrovasc Dis 24 (2007) 452-459