Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture

European Journal of Vascular and Endovascular Surgery

Volumn 45, Issue 2, 2013, Pages 121-127

  Salem, M K ^a   Vijaynagar, B ^a   Sayers, R D ^a   West, K ^b   Moore, D ^b   Robinson, T G ^a   Naylor, A R ^a   Bown, M J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Asymptomatic; Carotid; Gene expression; Histology

Indexed keywords

ACETYLSALICYLIC ACID; CHEMOKINE; CLOPIDOGREL; COMPLEMENTARY DNA; RNA POLYMERASE II; SIMVASTATIN;

ADULT; AGED; ARTICLE; BIOINFORMATICS; CAROTID ARTERY OBSTRUCTION; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CLINICAL ARTICLE; CLINICAL FEATURE; DOWN REGULATION; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; MALE; MICROARRAY ANALYSIS; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RNA EXTRACTION; SCORING SYSTEM; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; APOPTOSIS; ASYMPTOMATIC DISEASES; CAROTID ARTERIES; CAROTID STENOSIS; CHEMOKINES; CHI-SQUARE DISTRIBUTION; CLUSTER ANALYSIS; DISEASE PROGRESSION; ENDARTERECTOMY, CAROTID; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLAQUE, ATHEROSCLEROTIC; RUPTURE, SPONTANEOUS; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION;

EID: 84872612674     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2012.11.006     Document Type: Article

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