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Angewandte Chemie - International Edition

Volumn 55, Issue 8, 2016, Pages 2683-2687

Effects of Active-Site Modification and Quaternary Structure on the Regioselectivity of Catechol-O-Methyltransferase

(7) Law, Brian J C a Bennett, Matthew R a Thompson, Mark L a Levy, Colin a Shepherd, Sarah A a Leys, David a Micklefield, Jason a

a UNIVERSITY OF MANCHESTER (United Kingdom)

Author keywords

biocatalysis; enzyme structure; methyltransferases; protein engineering; regioselectivity

Indexed keywords

BIOCHEMICAL ENGINEERING; CRYSTALLOGRAPHY; ENZYMES; PHENOLS; REGIOSELECTIVITY;

ACTIVE SITE MODIFICATIONS; BIOCATALYSIS; BIOCATALYTIC PROCESS; CATECHOL-O-METHYLTRANSFERASE; ENZYME STRUCTURES; METHYLTRANSFERASES; PROTEIN ENGINEERING; QUATERNARY STRUCTURE;

X RAY CRYSTALLOGRAPHY;

CATECHOL METHYLTRANSFERASE;

CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM; PROTEIN QUATERNARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; CATECHOL O-METHYLTRANSFERASE; CRYSTALLOGRAPHY, X-RAY; PROTEIN STRUCTURE, QUATERNARY;

EID: 84958818299 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201508287 Document Type: Article

Times cited : (54)

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