Design of pH-Responsive Biomaterials to Enable the Oral Route of Hematological Factor IX

Annals of Biomedical Engineering

Volumn 44, Issue 6, 2016, Pages 1970-1982

  Horava, Sarena D ^a,b   Peppas, Nicholas A ^a,b,c  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Biomaterials; Drug delivery; Factor IX; Hydrogels

Indexed keywords

BIOMATERIALS; COSTS; DRUG DELIVERY; IONIC STRENGTH; PATIENT TREATMENT; POLYETHYLENE GLYCOLS;

FACTOR IX; HYDROGEL NETWORKS; LOADING CONDITION; ORAL ADMINISTRATION; PH RESPONSIVE BIOMATERIALS; PH-RESPONSIVE HYDROGELS; POLY (METHACRYLIC ACID); PROTEIN DEGRADATION;

HYDROGELS;

BIOMATERIAL; BLOOD CLOTTING FACTOR 9; DRUG CARRIER; MACROGOL; POLYMETHACRYLIC ACID; HYDROGEL; MACROGOL DERIVATIVE; POLYETHYLENE GLYCOL 1000; POLYMETHACRYLIC ACID DERIVATIVE;

ARTICLE; BIOENGINEERING; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; INCUBATION TIME; IONIC STRENGTH; ORAL DRUG ADMINISTRATION; PH; PH RESPONSIVE HYDROGEL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SYNTHESIS; CHEMISTRY; PHARMACOLOGY; PROCEDURES;

ADMINISTRATION, ORAL; DRUG DELIVERY SYSTEMS; FACTOR IX; HUMANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS;

EID: 84958767452     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-016-1566-x     Document Type: Article

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