Hypoxia-inducible factor-2α induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells

Inflammation Research

Volumn 65, Issue 6, 2016, Pages 439-448

  Ishizuka, Shinya ^a,b   Sakai, Tadahiro ^a   Hiraiwa, Hideki ^a   Hamada, Takashi ^a   Knudson, Warren ^b   Omachi, Takaaki ^a,c   Ono, Yohei ^a   Nakashima, Motoshige ^a   Matsukawa, Tetsuya ^a   Oda, Tomoyuki ^a   Takamatsu, Akira ^a   Yamashita, Satoshi ^a   Ishiguro, Naoki ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b EAST CAROLINA UNIVERSITY   (United States)

^c Department of Internal Medicine   (Japan)

Author keywords

HIF 2 ; Interleukin 1 ; Matrix metalloproteinase 13; Meniscal cell; Osteoarthritis; Type X collagen

Indexed keywords

COLLAGEN TYPE 10; COLLAGENASE 3; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INTERLEUKIN 1BETA; MESSENGER RNA; VASCULOTROPIN A; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; MMP13 PROTEIN, HUMAN;

ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HISTOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; KNEE MENISCUS; KNEE OSTEOARTHRITIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AGED; ARTICULAR CARTILAGE; CELL CULTURE; CYTOLOGY; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; OSTEOARTHRITIS;

AGED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARTILAGE, ARTICULAR; CELLS, CULTURED; COLLAGEN TYPE X; FEMALE; HUMANS; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASE 13; MENISCUS; MIDDLE AGED; OSTEOARTHRITIS; RNA, MESSENGER;

EID: 84958766300     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-016-0926-1     Document Type: Article

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