What does cartilage calcification tell us about osteoarthritis?

Journal of Rheumatology

Volumn 29, Issue 3, 2002, Pages 411-415

  Terkeltaub, Robert A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; INTERLEUKIN 1; NITRIC OXIDE; PARATHYROID HORMONE RELATED PROTEIN; PHOSPHATIDYLINOSITIDE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA;

ARTHROPLASTY; CALCIFICATION; CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CORRELATION ANALYSIS; CRYSTALLIZATION; EDITORIAL; HISTOPATHOLOGY; HUMAN; JOINT SURGERY; LONG TERM CARE; OSTEOARTHRITIS; PATHOPHYSIOLOGY; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNOVIAL FLUID LEVEL;

CALCINOSIS; CARTILAGE; HUMANS; OSTEOARTHRITIS;

EID: 0036199537     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (28)

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3. Submicroscopic crystals in osteoarthritic synovial fluids
4. Autopsy study correlating degree of osteoarthritis, synovitis and evidence of articular calcification
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6. New developments in the pathogenesis of articular cartilage calcification
7. Parathyroid hormone related protein (PTHrP) expression is abundant in osteoarthritic cartilage, and the PTHrP 1-173 isoform is selectively induced by TGFβ in articular chondrocytes, and suppresses extracellular inorganic pyrophosphate generation
8. The mitochondrion in osteoarthritis
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13. Role of the mouse ank gene in control of tissue calcification and arthritis
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15. Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member plasma cell membrane glycoprotein-1 (PC-1) is both a marker and pathogenic factor for knee meniscal cartilage matrix calcification
16. PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification
17. The nucleoside triphosphate pyrophosphohydrolase (NTPPPH) isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles
18. Insulin-like growth factor-1 suppresses pyrophosphate elaboration by transforming growth factor beta 1-stimulated chondrocytes and cartilage
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