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1
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84930643414
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A review of the pathophysiology and potential biomarkers for peripheral artery disease
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COI: 1:CAS:528:DC%2BC2MXht1egsbfO, PID: 25993296
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Krishna SM, Moxon JV, Golledge J. A review of the pathophysiology and potential biomarkers for peripheral artery disease. Int J Mol Sci. 2015;16:11294–322.
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Krishna, S.M.1
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Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients’ management
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Golledge J, Norman PE. Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients’ management. Curr Opin Cardiol. 2009;24:532–8.
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Golledge, J.1
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3
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0031583733
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Lower-limb arterial disease
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Golledge, J.1
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COI: 1:CAS:528:DC%2BD28XhtFymt7vK, PID: 16973970
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Golledge J, Muller J, Daugherty A, Norman P. Abdominal aortic aneurysm: pathogenesis and implications for management. Arterioscler Thromb Vasc Biol. 2006;26:2605–13.
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Golledge, J.1
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5
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34249849049
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Matrix biology of abdominal aortic aneurysms in diabetes: mechanisms underlying the negative association
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COI: 1:CAS:528:DC%2BD2sXls1SntL8%3D, PID: 17522995
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Norman PE, Davis TM, Le MT, Golledge J. Matrix biology of abdominal aortic aneurysms in diabetes: mechanisms underlying the negative association. Connect Tissue Res. 2007;48:125–31.
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Norman, P.E.1
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6
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77952861302
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Atherosclerosis and abdominal aortic aneurysm: cause, response, or common risk factors?
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COI: 1:CAS:528:DC%2BC3cXmt1alsbw%3D, PID: 20484703
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Golledge J, Norman PE. Atherosclerosis and abdominal aortic aneurysm: cause, response, or common risk factors? Arterioscler Thromb Vasc Biol. 2010;30:1075–7.
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Golledge, J.1
Norman, P.E.2
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7
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84926179234
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Family history as a risk factor for peripheral arterial disease
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PID: 25107577, This is one of the few studies to assess the association of family history with lower limb atherosclerosis associated occlusive disease and reported an odds ratio of 2.2
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Khaleghi M, Isseh IN, Bailey KR, Kullo IJ. Family history as a risk factor for peripheral arterial disease. Am J Cardiol. 2014;114:928–32. This is one of the few studies to assess the association of family history with lower limb atherosclerosis associated occlusive disease and reported an odds ratio of 2.2.
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Am J Cardiol
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Khaleghi, M.1
Isseh, I.N.2
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8
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77956224990
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Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm
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COI: 1:CAS:528:DC%2BC3cXhtFamsrbF, PID: 20347091
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Krishna SM, Dear AE, Norman PE, Golledge J. Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm. Atherosclerosis. 2010;212:16–29.
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Atherosclerosis
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Krishna, S.M.1
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9
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84927172523
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The relevance of epigenetics to occlusive cerebral and peripheral arterial disease
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Krishna SM, Trollope AF, Golledge J. The relevance of epigenetics to occlusive cerebral and peripheral arterial disease. Clin Sci (Lond). 2015;128:537–58.
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Clin Sci (Lond)
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Krishna, S.M.1
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10
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84878107564
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The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation
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COI: 1:CAS:528:DC%2BC3sXktVOrurY%3D, PID: 23497786
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Krishna SM, Dear A, Craig JM, Norman PE, Golledge J. The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation. Atherosclerosis. 2013;228:295–305.
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Atherosclerosis
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Krishna, S.M.1
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Golledge, J.5
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11
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84900400707
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Kloos W, Vogel B, Blessing E. MiRNAs in peripheral artery disease—something gripping this way comes. Vasa. 2014;43:163–70.
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Vasa
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Kloos, W.1
Vogel, B.2
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12
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84937125891
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MicroRNAs in Abdominal Aortic Aneurysm
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COI: 1:CAS:528:DC%2BC2MXhtFKrsbjL, PID: 23713862
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Adam M, Raaz U, Spin JM, Tsao PS. MicroRNAs in Abdominal Aortic Aneurysm. Curr Vasc Pharmacol. 2015;13:280–90.
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Adam, M.1
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13
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84876291921
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Genetics of abdominal aortic aneurysm
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PID: 23478885
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Golledge J, Kuivaniemi H. Genetics of abdominal aortic aneurysm. Curr Opin Cardiol. 2013;28:290–6.
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Curr Opin Cardiol
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Golledge, J.1
Kuivaniemi, H.2
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14
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84930634601
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Adventitial tertiary lymphoid organs as potential source of microRNA biomarkers for abdominal aortic aneurysm
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COI: 1:CAS:528:DC%2BC2MXht1egsbjE, PID: 25993295, This study used laser microdissection to look at MicroRNAs expressed in human AAA associated lymphoid tissue
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Spear R, Boytard L, Blervaque R, Chwastyniak M, Hot D, Vanhoutte J, et al. Adventitial tertiary lymphoid organs as potential source of microRNA biomarkers for abdominal aortic aneurysm. Int J Mol Sci. 2015;16:11276–93. This study used laser microdissection to look at MicroRNAs expressed in human AAA associated lymphoid tissue.
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Int J Mol Sci
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Spear, R.1
Boytard, L.2
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Hot, D.5
Vanhoutte, J.6
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15
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84891634059
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Identification and characterization of microRNAs in vascular smooth muscle cells from patients with abdominal aortic aneurysms
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PID: 23746831
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Cheuk BL, Cheng SW. Identification and characterization of microRNAs in vascular smooth muscle cells from patients with abdominal aortic aneurysms. J Vasc Surg. 2014;59:202–9.
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J Vasc Surg
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Cheuk, B.L.1
Cheng, S.W.2
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16
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84929027152
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Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease
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COI: 1:CAS:528:DC%2BC2MXotFChtL4%3D, PID: 25832031, This study identifies a number of circulating MicroRNAs associated with AAA and lower limb occlusive artery disease
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Stather PW, Sylvius N, Sidloff DA, Dattani N, Verissimo A, Wild JB, et al. Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease. Br J Surg. 2015;102:755–66. This study identifies a number of circulating MicroRNAs associated with AAA and lower limb occlusive artery disease.
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Stather, P.W.1
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Sidloff, D.A.3
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Verissimo, A.5
Wild, J.B.6
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17
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84880120745
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Tissue- and plasma-specific microRNA signatures for atherosclerotic abdominal aortic aneurysm
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PID: 23316282
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Shimamura, K.6
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18
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84894422143
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microRNA profiling in patients with abdominal aortic aneurysms: the significance of miR-155
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COI: 1:CAS:528:DC%2BC2cXjt1ags7g%3D, miR-155 was identified as upregulated within aortic biopsies of human AAA and also serum of patients that had AAAs
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Biros E, Moran CS, Wang Y, Walker PJ, Cardinal J, Golledge J. microRNA profiling in patients with abdominal aortic aneurysms: the significance of miR-155. Clin Sci (Lond). 2014;126:795–803. miR-155 was identified as upregulated within aortic biopsies of human AAA and also serum of patients that had AAAs.
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Clin Sci (Lond)
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Biros, E.1
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Golledge, J.6
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19
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84862174374
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MicroRNA expression signature in human abdominal aortic aneurysms
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COI: 1:CAS:528:DC%2BC3sXht1yqs7o%3D, PID: 22704053
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Pahl MC, Derr K, Gäbel G, Hinterseher I, Elmore JR, Schworer CM, et al. MicroRNA expression signature in human abdominal aortic aneurysms. BMC Med Genomics. 2012;5:25.
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20
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78650512343
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Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans
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COI: 1:CAS:528:DC%2BC3cXhsVGkurbI, PID: 20888330
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Li T, Cao H, Zhuang J, Wan J, Guan M, Yu B, et al. Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans. Clin Chim Acta. 2011;412:66–70.
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21
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84943553960
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Plasma microRNAs serve as potential biomarkers for abdominal aortic aneurysm
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COI: 1:CAS:528:DC%2BC2MXns1Kjsr8%3D, PID: 25916817, Three plasma microRNAs (miR-191-3p, miR-455-3p and miR-1281) were identified as having good sensitivity and specificity in identifying patients with AAA
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Zhang W, Shang T, Huang C, Yu T, Liu C, Qiao T, et al. Plasma microRNAs serve as potential biomarkers for abdominal aortic aneurysm. Clin Biochem. 2015;48:988–92. Three plasma microRNAs (miR-191-3p, miR-455-3p and miR-1281) were identified as having good sensitivity and specificity in identifying patients with AAA.
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Clin Biochem
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Zhang, W.1
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22
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84933050624
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Impairment of wound healing in patients with type 2 diabetes mellitus influences circulating microRNA patterns via inflammatory cytokines
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COI: 1:CAS:528:DC%2BC2MXos1Ojsb4%3D, PID: 25814674
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Dangwal S, Stratmann B, Bang C, Lorenzen JM, Kumarswamy R, Fiedler J, et al. Impairment of wound healing in patients with type 2 diabetes mellitus influences circulating microRNA patterns via inflammatory cytokines. Arterioscler Thromb Vasc Biol. 2015;35:1480–8.
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Fiedler, J.6
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23
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84892374667
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Differential microRNA expression profiles in peripheral arterial disease
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COI: 1:CAS:528:DC%2BC3sXhs1Cis7fI, PID: 24129592, This study identified a number of microRNAs with good diagnostic ability for lower limb arterial occlusive disease as judged by receiver operator characteristic curves
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Stather PW, Sylvius N, Wild JB, Choke E, Sayers RD, Bown MJ. Differential microRNA expression profiles in peripheral arterial disease. Circ Cardiovasc Genet. 2013;6:490–7. This study identified a number of microRNAs with good diagnostic ability for lower limb arterial occlusive disease as judged by receiver operator characteristic curves.
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Stather, P.W.1
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24
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84923380956
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miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development
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COI: 1:CAS:528:DC%2BC2MXktFent7o%3D, PID: 25358394, This study suggests that miR-24 inhibits AAA within a mouse model
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Maegdefessel L, Spin JM, Raaz U, Eken SM, Toh R, Azuma J, et al. miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development. Nat Commun. 2014;5:5214. This study suggests that miR-24 inhibits AAA within a mouse model.
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Nat Commun
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Maegdefessel, L.1
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25
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84927716262
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Role of miR-195 in aortic aneurysmal disease
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COI: 1:CAS:528:DC%2BC2cXhsl2msbjJ, PID: 25201911
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Zampetaki A, Attia R, Mayr U, Gomes RS, Phinikaridou A, Yin X, et al. Role of miR-195 in aortic aneurysmal disease. Circ Res. 2014;115:857–66.
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Yin, X.6
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26
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84903123297
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Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice
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COI: 1:CAS:528:DC%2BC2cXpvV2ktr4%3D, PID: 24812324
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Kim CW, Kumar S, Son DJ, Jang IH, Griendling KK, Jo H. Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice. Arterioscler Thromb Vasc Biol. 2014;34:1412–21.
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Jo, H.6
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27
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84857491474
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MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion
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PID: 22357537
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Maegdefessel L, Azuma J, Toh R, Deng A, Merk DR, Raiesdana A, et al. MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion. Sci Transl Med. 2012;4:122ra22.
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28
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84856552278
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Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development
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COI: 1:CAS:528:DC%2BC38XitVemu7s%3D, PID: 22269326, This study confirms that miR-29b limits AAA within multiple mouse models
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Maegdefessel L, Azuma J, Toh R, Merk DR, Deng A, Chin JT, et al. Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J Clin Invest. 2012;122:497–506. This study confirms that miR-29b limits AAA within multiple mouse models.
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J Clin Invest
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Chin, J.T.6
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29
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COI: 1:CAS:528:DC%2BC3MXhtlOnsLvL, PID: 21903938
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Boon RA, Seeger T, Heydt S, Fischer A, Hergenreider E, Horrevoets AJ, et al. MicroRNA-29 in aortic dilation: implications for aneurysm formation. Circ Res. 2011;109:1115–9.
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30
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84856029029
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miR-29b participates in early aneurysm development in Marfan syndrome
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COI: 1:CAS:528:DC%2BC38XhtVKrt74%3D, PID: 22116819
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Merk DR, Chin JT, Dake BA, Maegdefessel L, Miller MO, Kimura N, et al. miR-29b participates in early aneurysm development in Marfan syndrome. Circ Res. 2012;110:312–24.
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31
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84938484346
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MicroRNA-132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras-MAPK pathway
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COI: 1:CAS:528:DC%2BC2MXht1yrsLrO, PID: 25945589
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Lei Z, van Mil A, Brandt MM, Grundmann S, Hoefer I, Smits M, et al. MicroRNA-132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras-MAPK pathway. J Cell Mol Med. 2015;19:1994–2005.
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32
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84929378089
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MicroRNA-155 exerts cell-specific antiangiogenic but proarteriogenic effects during adaptive neovascularization
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COI: 1:CAS:528:DC%2BC2MXnvFOrsbg%3D, PID: 25850724
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Pankratz F, Bemtgen X, Zeiser R, Leonhardt F, Kreuzaler S, Hilgendorf I, et al. MicroRNA-155 exerts cell-specific antiangiogenic but proarteriogenic effects during adaptive neovascularization. Circulation. 2015;131:1575–89.
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33
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84921767137
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Inhibition of 14q32 microRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia
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COI: 1:CAS:528:DC%2BC2cXhs1SisrnN, PID: 25085941, This study suggests that gene silencing oligonucleotides targeted on 14q32 expressed microRNAs stimulate arteriogenesis in a mouse model of hind limb ischemia
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Welten SM, Bastiaansen AJ, de Jong RC, de Vries MR, Peters EA, Boonstra MC, et al. Inhibition of 14q32 microRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia. Circ Res. 2014;115:696–708. This study suggests that gene silencing oligonucleotides targeted on 14q32 expressed microRNAs stimulate arteriogenesis in a mouse model of hind limb ischemia.
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Circ Res
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Welten, S.M.1
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34
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84893048269
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Systemic delivery of miR-126 by miRNA-loaded Bubble liposomes for the treatment of hindlimb ischemia
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PID: 24457599
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Endo-Takahashi Y, Negishi Y, Nakamura A, Ukai S, Ooaku K, Oda Y, et al. Systemic delivery of miR-126 by miRNA-loaded Bubble liposomes for the treatment of hindlimb ischemia. Sci Rep. 2014;4:3883.
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35
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MicroRNA-93 controls perfusion recovery after hindlimb ischemia by modulating expression of multiple genes in the cell cycle pathway
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COI: 1:CAS:528:DC%2BC3sXnvVahsLc%3D, PID: 23559675
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Hazarika S, Farber CR, Dokun AO, Pitsillides AN, Wang T, Lye RJ, et al. MicroRNA-93 controls perfusion recovery after hindlimb ischemia by modulating expression of multiple genes in the cell cycle pathway. Circulation. 2013;127:1818–28.
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36
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84922390408
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The 106b∼25 microRNA cluster is essential for neovascularization after hindlimb ischaemia in mice
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PID: 23420866
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Semo J, Sharir R, Afek A, Avivi C, Barshack I, Maysel-Auslender S, et al. The 106b∼25 microRNA cluster is essential for neovascularization after hindlimb ischaemia in mice. Eur Heart J. 2014;35:3212–23.
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37
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Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia
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Yin KJ, Olsen K, Hamblin M, Zhang J, Schwendeman SP, Chen YE. Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia. J Biol Chem. 2012;287:27055–64.
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