MicroRNA-132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras-MAPK pathway

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 8, 2015, Pages 1994-2005

  Lei, Zhiyong ^a   van Mil, Alain ^a   Brandt, Maarten M ^b   Grundmann, Sebastian ^c   Hoefer, Imo ^a   Smits, Michiel ^a   el Azzouzi, Hamid ^a   Fukao, Taro ^d   Cheng, Caroline ^a,b   Doevendans, Pieter A ^a,e   Sluijter, Joost P G ^a,e  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^d MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^e ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Arteriogenesis; Hindlimb ischaemia; MiR 132 212; Ras MAPK

Indexed keywords

MICRORNA; MICRORNA 132; MICRORNA 212; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; UNCLASSIFIED DRUG; MIRN132 MICRORNA, MOUSE; MIRN212 MICRORNA, MOUSE; SIGNAL PEPTIDE;

ANGIOGENESIS; ANGIOGENESIS ASSAY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; GENE INACTIVATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HINDLIMB; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEG ISCHEMIA; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RASA1 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; SPRED1 GENE; SPRY1 GENE; VASCULAR RING; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENE SILENCING; GENETICS; HEK293 CELL LINE; HUMAN; IN VITRO STUDY; ISCHEMIA; KNOCKOUT MOUSE; METABOLISM; MORPHOGENESIS; PATHOLOGY; PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULARIZATION;

MUS;

ANIMALS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HINDLIMB; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IN VITRO TECHNIQUES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIA; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOGENESIS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; RAS PROTEINS; UP-REGULATION;

EID: 84938484346     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12586     Document Type: Article

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