The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

Cellular Signalling

Volumn 27, Issue 12, 2015, Pages 2579-2588

  Peeters, Miriam C ^a,b   Fokkelman, Michiel ^b   Boogaard, Bob ^b   Egerod, Kristoffer L ^a   van de Water, Bob ^b   IJzerman, Ad P ^b   Schwartz, Thue W ^a  

^a University of Copenhagen   (Denmark)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Activation mechanism; ADGRG2 GPR64; Adhesion G protein coupled receptor; Breast cancer; Cell adhesion; Cell migration

Indexed keywords

ADHESION G PROTEIN COUPLED RECEPTOR G2; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; GPR64 PROTEIN, HUMAN; RELB PROTEIN, HUMAN; SRE PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELB;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPROTEOLYSIS; BREAST CANCER CELL LINE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; HEK293 CELL LINE; HS578T CELL LINE; INTRACELLULAR SIGNALING; MDA MB 231 CELL LINE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; SERUM RESPONSIVE ELEMENT; STRUCTURE ACTIVITY RELATION; CELL MOTION; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; PROTEOLYSIS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTORS;

EID: 84958672500     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.08.015     Document Type: Article

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