ZnO nanoparticles induced inflammatory response and genotoxicity in human blood cells: A mechanistic approach

Food and Chemical Toxicology

Volumn 85, Issue , 2015, Pages 61-70

  Senapati, Violet Aileen ^a,b   Kumar, Ashutosh ^a   Gupta, Govind Sharan ^a   Pandey, Alok Kumar ^b   Dhawan, Alok ^a,b  

^a AHMEDABAD UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Cellular uptake; Cytokines; Immunotoxicity; Oxidative stress; Zinc oxide nanoparticles

Indexed keywords

GLUTATHIONE; INTERLEUKIN 1BETA; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; ZINC OXIDE NANOPARTICLE; BIOLOGICAL MARKER; IL1B PROTEIN, HUMAN; IMMUNOLOGIC FACTOR; METAL NANOPARTICLE; MUTAGENIC AGENT; NITRIC OXIDE; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR; ZINC OXIDE;

ARTICLE; CELL LEVEL; CHEMICAL ANALYSIS; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DISEASE ACTIVITY; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOTOXICITY; IN VITRO STUDY; INFLAMMATION; MICRONUCLEUS TEST; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MONOCYTE; NANOANALYSIS; NITROSATIVE STRESS; OXIDATIVE STRESS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING; ABSORPTION; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; PARTICLE SIZE; SIGNAL TRANSDUCTION; SURFACE PROPERTY; TOXICITY TESTING; ULTRASTRUCTURE;

ABSORPTION, PHYSIOLOGICAL; BIOMARKERS; CELL LINE; DNA DAMAGE; GLUTATHIONE; HUMANS; IMMUNOLOGIC FACTORS; INTERLEUKIN-1BETA; MAP KINASE SIGNALING SYSTEM; METAL NANOPARTICLES; MONOCYTES; MUTAGENS; NITRIC OXIDE; OXIDATIVE STRESS; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SURFACE PROPERTIES; TOXICITY TESTS; TUMOR NECROSIS FACTOR-ALPHA; ZINC OXIDE;

EID: 84958672481     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2015.06.018     Document Type: Article

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