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Volumn 9, Issue 2, 2016, Pages 204-209

DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects

Author keywords

Autism; DNA methylation; Epigenetics; HTR2A; Serotonin

Indexed keywords

SEROTONIN 2A RECEPTOR;

EID: 84958626332     PISSN: 19393792     EISSN: 19393806     Source Type: Journal    
DOI: 10.1002/aur.1519     Document Type: Article
Times cited : (19)

References (40)
  • 2
    • 82855166035 scopus 로고    scopus 로고
    • Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain
    • Bonnin, A., & Levitt, P. (2011). Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain. Neuroscience, 197, 1-7.
    • (2011) Neuroscience , vol.197 , pp. 1-7
    • Bonnin, A.1    Levitt, P.2
  • 4
    • 33847300921 scopus 로고    scopus 로고
    • Family-based association study of 5-HTTLPR and the 5-HT2A receptor gene polymorphisms with autism spectrum disorder in Korean trios
    • Cho, I.H., Yoo, H.J., Park, M., Lee, Y.S., & Kim, S.A. (2007). Family-based association study of 5-HTTLPR and the 5-HT2A receptor gene polymorphisms with autism spectrum disorder in Korean trios. Brain Research, 1139, 34-41.
    • (2007) Brain Research , vol.1139 , pp. 34-41
    • Cho, I.H.1    Yoo, H.J.2    Park, M.3    Lee, Y.S.4    Kim, S.A.5
  • 6
    • 83255166570 scopus 로고    scopus 로고
    • Increased DNA methylation of neuropsychiatric genes occurs in borderline personality disorder
    • Dammann, G., Teschler, S., Haag, T., Altmüller, F., Tuczek, F., & Dammann, R.H. (2011). Increased DNA methylation of neuropsychiatric genes occurs in borderline personality disorder. Epigenetics, 6, 1454-1462.
    • (2011) Epigenetics , vol.6 , pp. 1454-1462
    • Dammann, G.1    Teschler, S.2    Haag, T.3    Altmüller, F.4    Tuczek, F.5    Dammann, R.H.6
  • 7
    • 59649086138 scopus 로고    scopus 로고
    • Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: Analysis of suicidality in major psychosis
    • De Luca, V., Viggiano, E., Dhoot, R., Kennedy, J.L., & Wong, A.H.C. (2009). Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: Analysis of suicidality in major psychosis. Journal of Psychiatric Research, 43, 532-537.
    • (2009) Journal of Psychiatric Research , vol.43 , pp. 532-537
    • De Luca, V.1    Viggiano, E.2    Dhoot, R.3    Kennedy, J.L.4    Wong, A.H.C.5
  • 8
    • 79952706987 scopus 로고    scopus 로고
    • Functional genomics of serotonin receptor 2A (HTR2A): Interaction of polymorphism, methylation, expression and disease association
    • Falkenberg, V.R., Gurbaxani, B.M., Unger, E.R., & Rajeevan, M.S. (2011). Functional genomics of serotonin receptor 2A (HTR2A): Interaction of polymorphism, methylation, expression and disease association. Neuromolecular Medicine, 13, 66-76.
    • (2011) Neuromolecular Medicine , vol.13 , pp. 66-76
    • Falkenberg, V.R.1    Gurbaxani, B.M.2    Unger, E.R.3    Rajeevan, M.S.4
  • 9
    • 77951621358 scopus 로고    scopus 로고
    • Identification of a potential molecular link between the glucocorticoid and serotonergic signaling systems
    • Falkenberg, V.R., & Rajeevan, M.S. (2010). Identification of a potential molecular link between the glucocorticoid and serotonergic signaling systems. Journal of Molecular Neuroscience, 41, 322-327.
    • (2010) Journal of Molecular Neuroscience , vol.41 , pp. 322-327
    • Falkenberg, V.R.1    Rajeevan, M.S.2
  • 13
    • 70350006636 scopus 로고    scopus 로고
    • Analysis of serotonin receptor 2A gene (HTR2A): Association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes
    • Guhathakurta, S., Singh, A.S., Sinha, S., Chatterjee, A., Ahmed, S., Ghosh, S., & Usha, R. (2009). Analysis of serotonin receptor 2A gene (HTR2A): Association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes. Neurochemistry International, 55, 754-759.
    • (2009) Neurochemistry International , vol.55 , pp. 754-759
    • Guhathakurta, S.1    Singh, A.S.2    Sinha, S.3    Chatterjee, A.4    Ahmed, S.5    Ghosh, S.6    Usha, R.7
  • 15
    • 85034961029 scopus 로고    scopus 로고
    • Hyperserotonemia in autism: 5HT-regulating proteins
    • In V. Patel, V. Preedy & C. Martin (Eds.), Heidelberg: Springer-Verlag Berlin, SpringerReference.
    • Hranilovic, D., & Blazevic, S. (2012). Hyperserotonemia in autism: 5HT-regulating proteins. In V. Patel, V. Preedy & C. Martin (Eds.), The comprehensive guide to autism. Heidelberg: Springer-Verlag Berlin, SpringerReference.
    • (2012) The comprehensive guide to autism
    • Hranilovic, D.1    Blazevic, S.2
  • 18
    • 75949111786 scopus 로고    scopus 로고
    • Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces
    • Jiang, M., Zhang, Y., Fei, J., Chang, X., Fan, W., Qian, X., ... Lu, D. (2010). Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces. Laboratory Investigation, 90, 282-290.
    • (2010) Laboratory Investigation , vol.90 , pp. 282-290
    • Jiang, M.1    Zhang, Y.2    Fei, J.3    Chang, X.4    Fan, W.5    Qian, X.6    Lu, D.7
  • 19
    • 0037311477 scopus 로고    scopus 로고
    • Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders
    • Marek, G.J., Carpenter, L.L., McDougle, C.J., & Price, L.H. (2003). Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders. Neuropsychopharmacology, 28, 402-412.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 402-412
    • Marek, G.J.1    Carpenter, L.L.2    McDougle, C.J.3    Price, L.H.4
  • 22
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki, J.R., Vincent, P.C., & Clark, S.J. (1999). Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Research, 59, 3730-3740.
    • (1999) Cancer Research , vol.59 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 23
    • 85047699588 scopus 로고    scopus 로고
    • Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: An in vivo SPECT study
    • Murphy, D.L., Daly, E., Schmitz, N., Toal, F., Murphy, K.M., Curran, S., ... Travis, M. (2006). Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: An in vivo SPECT study. American Journal of Psychiatry, 163, 934-936.
    • (2006) American Journal of Psychiatry , vol.163 , pp. 934-936
    • Murphy, D.L.1    Daly, E.2    Schmitz, N.3    Toal, F.4    Murphy, K.M.5    Curran, S.6    Travis, M.7
  • 24
    • 34247095504 scopus 로고    scopus 로고
    • Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation
    • Nagarajan, R., Hogart, A., Gwye, Y., Martin, M., & Lasalle, J.M. (2006). Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics, 1, e1-11.
    • (2006) Epigenetics , vol.1 , pp. e1-11
    • Nagarajan, R.1    Hogart, A.2    Gwye, Y.3    Martin, M.4    Lasalle, J.M.5
  • 25
    • 77955803943 scopus 로고    scopus 로고
    • Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
    • Nguyen, A., Rauch, T.A., Pfeifer, G.P., & Hu, V.W. (2010). Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. The FASEB Journal, 24, 3036-3051.
    • (2010) The FASEB Journal , vol.24 , pp. 3036-3051
    • Nguyen, A.1    Rauch, T.A.2    Pfeifer, G.P.3    Hu, V.W.4
  • 26
    • 84890793543 scopus 로고    scopus 로고
    • Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism
    • Oblak, A., Gibbs, T.T., & Blatt, G.J. (2013). Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism. Autism Research, 6, 571-583.
    • (2013) Autism Research , vol.6 , pp. 571-583
    • Oblak, A.1    Gibbs, T.T.2    Blatt, G.J.3
  • 28
    • 84927154636 scopus 로고    scopus 로고
    • The developmental basis of epigenetic regulation of HTR2A and psychiatric outcomes
    • Paquette, A.G., & Marsit, C.J. (2014). The developmental basis of epigenetic regulation of HTR2A and psychiatric outcomes. Journal of Cellular Biochemistry, 115, 2065-2072.
    • (2014) Journal of Cellular Biochemistry , vol.115 , pp. 2065-2072
    • Paquette, A.G.1    Marsit, C.J.2
  • 29
    • 31844438690 scopus 로고    scopus 로고
    • Allele C specific methylation of the 5-HT2A receptor gene: Evidence for correlation with its expression and expression of DNA methylase DNMT1
    • Polesskaya, O.O., Aston, C., & Sokolov, B.P (2006). Allele C specific methylation of the 5-HT2A receptor gene: Evidence for correlation with its expression and expression of DNA methylase DNMT1. Journal of Neuroscience Research, 83, 362-373.
    • (2006) Journal of Neuroscience Research , vol.83 , pp. 362-373
    • Polesskaya, O.O.1    Aston, C.2    Sokolov, B.P.3
  • 30
    • 84886241144 scopus 로고    scopus 로고
    • Epigenetics, autism spectrum, and neurodevelopmental disorders
    • Rangasamy, S., D'Mello, S.R., & Narayanan, V. (2013). Epigenetics, autism spectrum, and neurodevelopmental disorders. Neurotherapeutics, 10, 742-756.
    • (2013) Neurotherapeutics , vol.10 , pp. 742-756
    • Rangasamy, S.1    D'Mello, S.R.2    Narayanan, V.3
  • 32
    • 33749007122 scopus 로고    scopus 로고
    • Epigenetics of autism spectrum disorders
    • Schanen, N.C. (2006). Epigenetics of autism spectrum disorders. Human Molecular Genetics, 15, R138-R150.
    • (2006) Human Molecular Genetics , vol.15 , pp. R138-R150
    • Schanen, N.C.1
  • 34
    • 84905909773 scopus 로고    scopus 로고
    • Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder
    • Smith, R.M., Banks, W., Hansen, E., Sadee, W., & Herman, G.E. (2014). Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism Research, 7, 459-467.
    • (2014) Autism Research , vol.7 , pp. 459-467
    • Smith, R.M.1    Banks, W.2    Hansen, E.3    Sadee, W.4    Herman, G.E.5
  • 35
    • 84874533799 scopus 로고    scopus 로고
    • Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex
    • Smith, R.M., Papp, A.C., Webb, A., Ruble, C.L., Munsie, L.M., Nisenbaum, L.K., ... Sadee, W. (2013). Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex. Biological Psychiatry, 73, 546-554.
    • (2013) Biological Psychiatry , vol.73 , pp. 546-554
    • Smith, R.M.1    Papp, A.C.2    Webb, A.3    Ruble, C.L.4    Munsie, L.M.5    Nisenbaum, L.K.6    Sadee, W.7
  • 36
    • 15144353438 scopus 로고    scopus 로고
    • A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter
    • Spurlock, G., Heils, A., & Holmans, P. (1998). A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter. Molecular Psychiatry, 3, 42-49.
    • (1998) Molecular Psychiatry , vol.3 , pp. 42-49
    • Spurlock, G.1    Heils, A.2    Holmans, P.3
  • 40
    • 84863768068 scopus 로고    scopus 로고
    • DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression
    • Zill, P., Baghai, T.C., Schüle, C., Born, C., Früstück, C., Büttner, A., ... Bondy, B. (2012). DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. PloS One, 7, e40479.
    • (2012) PloS One , vol.7 , pp. e40479
    • Zill, P.1    Baghai, T.C.2    Schüle, C.3    Born, C.4    Früstück, C.5    Büttner, A.6    Bondy, B.7


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