Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex

Biological Psychiatry

Volumn 73, Issue 6, 2013, Pages 546-554

  Smith, Ryan M ^a   Papp, Audrey C ^a   Webb, Amy ^b   Ruble, Cara L ^c   Munsie, Leanne M ^c   Nisenbaum, Laura K ^c   Kleinman, Joel E ^d   Lipska, Barbara K ^d   Sadee, Wolfgang ^a,b  

^a The College of Medicine   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

5 HT2A; depression; HTR2A; mRNA expression; schizophrenia; serotonin

Indexed keywords

CITALOPRAM; COMPLEMENTARY DNA; SEROTONIN 2A RECEPTOR;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; AFRICAN AMERICAN; ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CPG ISLAND; DEPRESSION; DISEASE MARKER; DISEASE SEVERITY; DNA METHYLATION; DNA SEQUENCE; EXON; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; HAPLOTYPE; HEART PALPITATION; HERITABILITY; HISPANIC; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULA; POLYADENYLATION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE TRAIT LOCUS; RNA SEQUENCE; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ALLELES; CEREBRAL CORTEX; CLINICAL TRIALS AS TOPIC; DEPRESSION; EXONS; GENE EXPRESSION REGULATION; GENETIC VARIATION; HUMANS; METHYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN UPTAKE INHIBITORS; TRANSCRIPTOME; UNTRANSLATED REGIONS;

EID: 84874533799     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.09.028     Document Type: Article

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