Iron mitigates DMT1-mediated manganese cytotoxicity via the ASK1-JNK signaling axis: Implications of iron supplementation for manganese toxicity

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Tai, Yee Kit ^a   Chew, Katherine C M ^a   Tan, Bryce W Q ^a   Lim, Kah Leong ^a,c,d   Soong, Tuck Wah ^a,b,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL NEUROSCIENCE INSTITUTE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CATION TRANSPORT PROTEIN; FERRITIN; IRON; MANGANESE; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; STRESS ACTIVATED PROTEIN KINASE; THIOREDOXIN;

AUTOPHAGY; BIOLOGICAL MODEL; CELL LINE; CELL SURVIVAL; DIETARY SUPPLEMENT; GENE EXPRESSION; GENETICS; HUMAN; INTOXICATION; LYSOSOME; METABOLISM; NERVE CELL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

AUTOPHAGY; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; CELL LINE; CELL SURVIVAL; DIETARY SUPPLEMENTS; FERRITINS; GENE EXPRESSION; HUMANS; IRON; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYSOSOMES; MANGANESE; MANGANESE POISONING; MAP KINASE KINASE KINASE 5; MODELS, BIOLOGICAL; NEURONS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; THIOREDOXINS;

EID: 84958280986     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21113     Document Type: Article

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