Identification of 3 H -naphtho[1,2,3- de ]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1)

Journal of Medicinal Chemistry

Volumn 54, Issue 8, 2011, Pages 2680-2686

  Volynets, Galyna P ^a   Chekanov, Maksym O ^a,b   Synyugin, Anatoliy R ^a,b   Golub, Andriy G ^a   Kukharenko, Oleksandr P ^a   Bdzhola, Volodymyr G ^a   Yarmoluk, Sergiy M ^a,b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b Otava Ltd   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; APOPTOSIS SIGNAL REGULATING KINASE 1 INHIBITOR; ENZYME INHIBITOR; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; MAP3K5 PROTEIN, MOUSE; PROTEIN KINASE INHIBITOR; QUINOLONE DERIVATIVE;

ARTICLE; COMPETITIVE INHIBITION; DEGENERATIVE DISEASE; DRUG ACTIVITY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; HEART DISEASE; HUMAN; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; MOLECULAR DYNAMICS; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; MAGNETIC RESONANCE SPECTROSCOPY; MAP KINASE KINASE KINASE 5; MICE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN KINASE INHIBITORS; QUINOLONES;

EID: 79955460731     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200117h     Document Type: Article

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