-
3
-
-
0026760990
-
Deep-vein thrombosis and the incidence of subsequent symptomatic cancer
-
Prandoni P, Lensing AW, Buller HR, Cogo A, Prins MH, Cattelan AM, Cuppini S, Noventa F, ten Cate JW. Deep-vein thrombosis and the incidence of subsequent symptomatic cancer. N Engl J Med 1992; 327: 1128-33.
-
(1992)
N Engl J Med
, vol.327
, pp. 1128-1133
-
-
Prandoni, P.1
Lensing, A.W.2
Buller, H.R.3
Cogo, A.4
Prins, M.H.5
Cattelan, A.M.6
Cuppini, S.7
Noventa, F.8
ten Cate, J.W.9
-
4
-
-
69549103137
-
Cancer cell-derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo
-
Thomas GM, Panicot-Dubois L, Lacroix R, Dignat-George F, Lombardo D, Dubois C. Cancer cell-derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo. J Exp Med 2009; 206: 1913-27.
-
(2009)
J Exp Med
, vol.206
, pp. 1913-1927
-
-
Thomas, G.M.1
Panicot-Dubois, L.2
Lacroix, R.3
Dignat-George, F.4
Lombardo, D.5
Dubois, C.6
-
7
-
-
84922041685
-
Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells
-
Tinholt M, Stavik B, Louch W, Carlson CR, Sletten M, Ruf W, Skretting G, Sandset PM, Iversen N. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells. PLoS One 2015; 10: e0117404.
-
(2015)
PLoS One
, vol.10
, pp. e0117404
-
-
Tinholt, M.1
Stavik, B.2
Louch, W.3
Carlson, C.R.4
Sletten, M.5
Ruf, W.6
Skretting, G.7
Sandset, P.M.8
Iversen, N.9
-
8
-
-
84872135966
-
TFPIalpha and TFPIbeta are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity
-
Stavik B, Tinholt M, Sletten M, Skretting G, Sandset PM, Iversen N. TFPIalpha and TFPIbeta are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity. J Hematol Oncol 2013; 6: 5.
-
(2013)
J Hematol Oncol
, vol.6
, pp. 5
-
-
Stavik, B.1
Tinholt, M.2
Sletten, M.3
Skretting, G.4
Sandset, P.M.5
Iversen, N.6
-
9
-
-
84886099738
-
Tumour expression of tissue factor and tissue factor pathway inhibitor in ovarian cancer - relationship with venous thrombosis risk
-
Abu Saadeh F, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N. Tumour expression of tissue factor and tissue factor pathway inhibitor in ovarian cancer - relationship with venous thrombosis risk. Thromb Res 2013; 132: 627-34.
-
(2013)
Thromb Res
, vol.132
, pp. 627-634
-
-
Abu Saadeh, F.1
Norris, L.2
O'Toole, S.3
Mohamed, B.M.4
Langhe, R.5
O'Leary, J.6
Gleeson, N.7
-
10
-
-
74249118444
-
Expression of tissue factor pathway inhibitor (TFPI) in human breast and colon cancer tissue
-
Sierko E, Wojtukiewicz MZ, Zimnoch L, Kisiel W. Expression of tissue factor pathway inhibitor (TFPI) in human breast and colon cancer tissue. Thromb Haemost 2010; 103: 198-204.
-
(2010)
Thromb Haemost
, vol.103
, pp. 198-204
-
-
Sierko, E.1
Wojtukiewicz, M.Z.2
Zimnoch, L.3
Kisiel, W.4
-
11
-
-
84907879683
-
Signaling pathways in breast cancer: therapeutic targeting of the microenvironment
-
Nwabo Kamdje AH, Muller JM, Lukong KE. Signaling pathways in breast cancer: therapeutic targeting of the microenvironment. Cell Signal 2014; 26: 2843-56.
-
(2014)
Cell Signal
, vol.26
, pp. 2843-2856
-
-
Nwabo Kamdje, A.H.1
Muller, J.M.2
Lukong, K.E.3
-
12
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010; 29: 625-34.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
14
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
15
-
-
0036320934
-
2-regulated gene expression
-
2-regulated gene expression. FASEB J 2002; 16: 1151-62.
-
(2002)
FASEB J
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
16
-
-
0035812772
-
HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus
-
Semenza GL. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 2001; 107: 1-3.
-
(2001)
Cell
, vol.107
, pp. 1-3
-
-
Semenza, G.L.1
-
17
-
-
13944256192
-
PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma
-
Rong Y, Post DE, Pieper RO, Durden DL, van Meir EG, Brat DJ. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Res 2005; 65: 1406-13.
-
(2005)
Cancer Res
, vol.65
, pp. 1406-1413
-
-
Rong, Y.1
Post, D.E.2
Pieper, R.O.3
Durden, D.L.4
van Meir, E.G.5
Brat, D.J.6
-
18
-
-
84878200731
-
Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells
-
Eisenreich A, Zakrzewicz A, Huber K, Thierbach H, Pepke W, Goldin-Lang P, Schultheiss HP, Pries A, Rauch U. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol Rep 2013; 30: 462-70.
-
(2013)
Oncol Rep
, vol.30
, pp. 462-470
-
-
Eisenreich, A.1
Zakrzewicz, A.2
Huber, K.3
Thierbach, H.4
Pepke, W.5
Goldin-Lang, P.6
Schultheiss, H.P.7
Pries, A.8
Rauch, U.9
-
19
-
-
84881030198
-
Hypoxia influences stem cell-like properties in multidrug resistant K562 leukemic cells
-
Cui XY, Skretting G, Jing Y, Sun H, Sandset PM, Sun L. Hypoxia influences stem cell-like properties in multidrug resistant K562 leukemic cells. Blood Cells Mol Dis 2013; 51: 177-84.
-
(2013)
Blood Cells Mol Dis
, vol.51
, pp. 177-184
-
-
Cui, X.Y.1
Skretting, G.2
Jing, Y.3
Sun, H.4
Sandset, P.M.5
Sun, L.6
-
20
-
-
0036882302
-
2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2
-
2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. Ann N Y Acad Sci 2002; 973: 443-7.
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 443-447
-
-
Piret, J.P.1
Mottet, D.2
Raes, M.3
Michiels, C.4
-
21
-
-
77953616244
-
Functional characterization of polymorphisms in the human TFPI gene
-
Skretting G, Stavik B, Landvik NE, Myklebust CF, Iversen N, Zienolddiny S, Sandset PM. Functional characterization of polymorphisms in the human TFPI gene. Biochem Biophys Res Commun 2010; 397: 106-11.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, pp. 106-111
-
-
Skretting, G.1
Stavik, B.2
Landvik, N.E.3
Myklebust, C.F.4
Iversen, N.5
Zienolddiny, S.6
Sandset, P.M.7
-
22
-
-
84928890805
-
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
-
Tinholt M, Vollan HK, Sahlberg KK, Jernstrom S, Kaveh F, Lingjaerde OC, Karesen R, Sauer T, Kristensen V, Borresen-Dale AL, Sandset PM, Iversen N. Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF. Breast Cancer Res 2015; 17: 44.
-
(2015)
Breast Cancer Res
, vol.17
, pp. 44
-
-
Tinholt, M.1
Vollan, H.K.2
Sahlberg, K.K.3
Jernstrom, S.4
Kaveh, F.5
Lingjaerde, O.C.6
Karesen, R.7
Sauer, T.8
Kristensen, V.9
Borresen-Dale, A.L.10
Sandset, P.M.11
Iversen, N.12
-
23
-
-
7944224442
-
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
-
Tang N, Wang L, Esko J, Giordano FJ, Huang Y, Gerber HP, Ferrara N, Johnson RS. Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 2004; 6: 485-95.
-
(2004)
Cancer Cell
, vol.6
, pp. 485-495
-
-
Tang, N.1
Wang, L.2
Esko, J.3
Giordano, F.J.4
Huang, Y.5
Gerber, H.P.6
Ferrara, N.7
Johnson, R.S.8
-
24
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-5.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
25
-
-
0037208166
-
TRANSFAC: transcriptional regulation, from patterns to profiles
-
Matys V, Fricke E, Geffers R, Gossling E, Haubrock M, Hehl R, Hornischer K, Karas D, Kel AE, Kel-Margoulis OV, Kloos DU, Land S, Lewicki-Potapov B, Michael H, Munch R, Reuter I, Rotert S, Saxel H, Scheer M, Thiele S, et al. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res 2003; 31: 374-8.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 374-378
-
-
Matys, V.1
Fricke, E.2
Geffers, R.3
Gossling, E.4
Haubrock, M.5
Hehl, R.6
Hornischer, K.7
Karas, D.8
Kel, A.E.9
Kel-Margoulis, O.V.10
Kloos, D.U.11
Land, S.12
Lewicki-Potapov, B.13
Michael, H.14
Munch, R.15
Reuter, I.16
Rotert, S.17
Saxel, H.18
Scheer, M.19
Thiele, S.20
more..
-
27
-
-
58649112595
-
Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia
-
Morote-Garcia JC, Rosenberger P, Nivillac NM, Coe IR, Eltzschig HK. Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia. Gastroenterology 2009; 136: 607-18.
-
(2009)
Gastroenterology
, vol.136
, pp. 607-618
-
-
Morote-Garcia, J.C.1
Rosenberger, P.2
Nivillac, N.M.3
Coe, I.R.4
Eltzschig, H.K.5
-
28
-
-
58249123287
-
Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium
-
Zheng W, Kuhlicke J, Jackel K, Eltzschig HK, Singh A, Sjoblom M, Riederer B, Weinhold C, Seidler U, Colgan SP, Karhausen J. Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium. FASEB J 2009; 23: 204-13.
-
(2009)
FASEB J
, vol.23
, pp. 204-213
-
-
Zheng, W.1
Kuhlicke, J.2
Jackel, K.3
Eltzschig, H.K.4
Singh, A.5
Sjoblom, M.6
Riederer, B.7
Weinhold, C.8
Seidler, U.9
Colgan, S.P.10
Karhausen, J.11
-
29
-
-
78650654512
-
Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD
-
Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D. Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD. J Immunol 2010; 185: 6306-16.
-
(2010)
J Immunol
, vol.185
, pp. 6306-6316
-
-
Hindryckx, P.1
De Vos, M.2
Jacques, P.3
Ferdinande, L.4
Peeters, H.5
Olievier, K.6
Bogaert, S.7
Brinkman, B.8
Vandenabeele, P.9
Elewaut, D.10
Laukens, D.11
-
30
-
-
50149097983
-
Hypoxia, HIF1 and glucose metabolism in the solid tumour
-
Denko NC. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer 2008; 8: 705-13.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 705-713
-
-
Denko, N.C.1
-
32
-
-
70649108815
-
Factors interacting with HIF-1alpha mRNA: novel therapeutic targets
-
Galban S, Gorospe M. Factors interacting with HIF-1alpha mRNA: novel therapeutic targets. Curr Pharm Des 2009; 15: 3853-60.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 3853-3860
-
-
Galban, S.1
Gorospe, M.2
-
33
-
-
21344438419
-
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)
-
Greijer AE, van der Groep P, Kemming D, Shvarts A, Semenza GL, Meijer GA, van de Wiel MA, Belien JA, van Diest PJ, van der Wall E. Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). J Pathol 2005; 206: 291-304.
-
(2005)
J Pathol
, vol.206
, pp. 291-304
-
-
Greijer, A.E.1
van der Groep, P.2
Kemming, D.3
Shvarts, A.4
Semenza, G.L.5
Meijer, G.A.6
van de Wiel, M.A.7
Belien, J.A.8
van Diest, P.J.9
van der Wall, E.10
-
34
-
-
84655161946
-
HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression
-
Keith B, Johnson RS, Simon MC. HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer 2012; 12: 9-22.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
35
-
-
84871079890
-
Venous thromboembolism in cancer clinical trials: recommendation for standardized reporting and analysis
-
subcommittee on Haemostasis and Malignancy for the SSC of the ISTH
-
Carrier M, Khorana AA, Zwicker JI, Lyman GH, Le Gal G, Lee AY; subcommittee on Haemostasis and Malignancy for the SSC of the ISTH. Venous thromboembolism in cancer clinical trials: recommendation for standardized reporting and analysis. J Thromb Haemost 2012; 10: 2599-601.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 2599-2601
-
-
Carrier, M.1
Khorana, A.A.2
Zwicker, J.I.3
Lyman, G.H.4
Le Gal, G.5
Lee, A.Y.6
-
36
-
-
11144357000
-
Identification and characterization of a very low density lipoprotein receptor-binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activity
-
Hembrough TA, Ruiz JF, Swerdlow BM, Swartz GM, Hammers HJ, Zhang L, Plum SM, Williams MS, Strickland DK, Pribluda VS. Identification and characterization of a very low density lipoprotein receptor-binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activity. Blood 2004; 103: 3374-80.
-
(2004)
Blood
, vol.103
, pp. 3374-3380
-
-
Hembrough, T.A.1
Ruiz, J.F.2
Swerdlow, B.M.3
Swartz, G.M.4
Hammers, H.J.5
Zhang, L.6
Plum, S.M.7
Williams, M.S.8
Strickland, D.K.9
Pribluda, V.S.10
-
37
-
-
80051656386
-
Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility
-
Stavik B, Skretting G, Aasheim HC, Tinholt M, Zernichow L, Sletten M, Sandset PM, Iversen N. Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility. BMC Cancer 2011; 11: 357.
-
(2011)
BMC Cancer
, vol.11
, pp. 357
-
-
Stavik, B.1
Skretting, G.2
Aasheim, H.C.3
Tinholt, M.4
Zernichow, L.5
Sletten, M.6
Sandset, P.M.7
Iversen, N.8
-
39
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 2006; 441: 437-43.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
40
-
-
84905643012
-
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
-
Wang T, Gilkes DM, Takano N, Xiang L, Luo W, Bishop CJ, Chaturvedi P, Green JJ, Semenza GL. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci USA 2014; 111: E3234-42.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E3234-E3242
-
-
Wang, T.1
Gilkes, D.M.2
Takano, N.3
Xiang, L.4
Luo, W.5
Bishop, C.J.6
Chaturvedi, P.7
Green, J.J.8
Semenza, G.L.9
-
41
-
-
84900300482
-
TFPI1 mediates resistance to doxorubicin in breast cancer cells by inducing a hypoxic-like response
-
Davies GF, Berg A, Postnikoff SD, Wilson HL, Arnason TG, Kusalik A, Harkness TA. TFPI1 mediates resistance to doxorubicin in breast cancer cells by inducing a hypoxic-like response. PLoS One 2014; 9: e84611.
-
(2014)
PLoS One
, vol.9
, pp. e84611
-
-
Davies, G.F.1
Berg, A.2
Postnikoff, S.D.3
Wilson, H.L.4
Arnason, T.G.5
Kusalik, A.6
Harkness, T.A.7
-
42
-
-
84906956919
-
The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth
-
Ueda J, Ho JC, Lee KL, Kitajima S, Yang H, Sun W, Fukuhara N, Zaiden N, Chan SL, Tachibana M, Shinkai Y, Kato H, Poellinger L. The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth. Mol Cell Biol 2014; 34: 3702-20.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 3702-3720
-
-
Ueda, J.1
Ho, J.C.2
Lee, K.L.3
Kitajima, S.4
Yang, H.5
Sun, W.6
Fukuhara, N.7
Zaiden, N.8
Chan, S.L.9
Tachibana, M.10
Shinkai, Y.11
Kato, H.12
Poellinger, L.13
|