메뉴 건너뛰기




Volumn 1862, Issue 4, 2016, Pages 511-517

Lipoic acid improves neuronal insulin signalling and rescues cognitive function regulating VGlut1 expression in high-fat-fed rats: Implications for Alzheimer's disease

Author keywords

Cognitive deficits; High fat diet; Insulin; Ketone bodies; VGlut1

Indexed keywords

GLUTAMIC ACID; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; KETONE BODY; PROTEIN KINASE B; THIOCTIC ACID; VESICULAR GLUTAMATE TRANSPORTER 1;

EID: 84958191290     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2016.01.004     Document Type: Article
Times cited : (23)

References (53)
  • 1
    • 84922725184 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and Alzheimer's disease
    • Barbagallo M., Dominguez L.J. Type 2 diabetes mellitus and Alzheimer's disease. World J. Diabetes 2014, 5:889-893.
    • (2014) World J. Diabetes , vol.5 , pp. 889-893
    • Barbagallo, M.1    Dominguez, L.J.2
  • 2
    • 51649088252 scopus 로고    scopus 로고
    • Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment
    • Caselli R.J., Chen K., Lee W., Alexander G.E., Reiman E.M. Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment. Arch. Neurol. 2008, 65:1231-1236.
    • (2008) Arch. Neurol. , vol.65 , pp. 1231-1236
    • Caselli, R.J.1    Chen, K.2    Lee, W.3    Alexander, G.E.4    Reiman, E.M.5
  • 5
    • 0025856239 scopus 로고
    • Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a cross-sectional comparison against advanced late-onset and incipient early-onset cases
    • Hoyer S., Nitsch R., Oesterreich K. Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a cross-sectional comparison against advanced late-onset and incipient early-onset cases. J. Neural Transm. Park. Dis. Dement. Sect. 1991, 3:1-14.
    • (1991) J. Neural Transm. Park. Dis. Dement. Sect. , vol.3 , pp. 1-14
    • Hoyer, S.1    Nitsch, R.2    Oesterreich, K.3
  • 10
    • 59449095272 scopus 로고    scopus 로고
    • Glutamate acting on N-methyl-d-aspartate receptors attenuates insulin-like growth factor-receptor tyrosine phosphorylation and its survival signalling properties in rat hippocampal neurons
    • Zheng W.H., Quirion R. Glutamate acting on N-methyl-d-aspartate receptors attenuates insulin-like growth factor-receptor tyrosine phosphorylation and its survival signalling properties in rat hippocampal neurons. J. Biol. Chem. 2009, 284:855-861.
    • (2009) J. Biol. Chem. , vol.284 , pp. 855-861
    • Zheng, W.H.1    Quirion, R.2
  • 11
    • 0027302996 scopus 로고
    • Glutamate: its role in learning, memory, and the aging brain
    • McEntee W.J., Crook T.H. Glutamate: its role in learning, memory, and the aging brain. Psychopharmacology 1993, 111:391-401.
    • (1993) Psychopharmacology , vol.111 , pp. 391-401
    • McEntee, W.J.1    Crook, T.H.2
  • 12
  • 13
    • 77950240594 scopus 로고    scopus 로고
    • Neurochemical basis for symptomatic treatment of Alzheimer's disease
    • Francis P.T., Ramírez M.J., Lai M.K. Neurochemical basis for symptomatic treatment of Alzheimer's disease. Neuropharmacology 2010, 59:221-229.
    • (2010) Neuropharmacology , vol.59 , pp. 221-229
    • Francis, P.T.1    Ramírez, M.J.2    Lai, M.K.3
  • 16
    • 84879879175 scopus 로고    scopus 로고
    • Altered synapses and gliotransmission in Alzheimer's disease and AD model mice
    • Mitew S., Kirkcaldie M.T.K., Dickson T.C., Vickers J.C. Altered synapses and gliotransmission in Alzheimer's disease and AD model mice. Neurobiol. Aging 2013, 34:2341-2351.
    • (2013) Neurobiol. Aging , vol.34 , pp. 2341-2351
    • Mitew, S.1    Kirkcaldie, M.T.K.2    Dickson, T.C.3    Vickers, J.C.4
  • 19
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao J., Irwin R.W., Zhao L., Nilsen J., Hamilton R.T., Brinton R.D. Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:14670-14675.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6
  • 20
    • 84920771529 scopus 로고    scopus 로고
    • α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects. Biochim. Biophys
    • Fernández-Galilea M., Pérez-Matute P., Prieto-Hontoria P.L., Houssier M., Burrell M.A., Langin D., Martínez J.A., Moreno-Aliaga M.J. α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects. Biochim. Biophys. Acta 2015, 1851:273-281.
    • (2015) Acta , vol.1851 , pp. 273-281
    • Fernández-Galilea, M.1    Pérez-Matute, P.2    Prieto-Hontoria, P.L.3    Houssier, M.4    Burrell, M.A.5    Langin, D.6    Martínez, J.A.7    Moreno-Aliaga, M.J.8
  • 24
    • 84931266653 scopus 로고    scopus 로고
    • Object recognition test for studying cognitive impairments in animal models of Alzheimer's disease
    • Bengoetxea X., Rodriguez-Perdigon M., Ramirez M.J. Object recognition test for studying cognitive impairments in animal models of Alzheimer's disease. Front. Biosci. Sch. Ed. 2015, 7:10-29.
    • (2015) Front. Biosci. Sch. Ed. , vol.7 , pp. 10-29
    • Bengoetxea, X.1    Rodriguez-Perdigon, M.2    Ramirez, M.J.3
  • 25
    • 46749158301 scopus 로고    scopus 로고
    • High-fat diets promote insulin resistance through cytokine gene expression in growing female rats
    • Flanagan A.M., Brown J.L., Santiago C.A., Aad P.Y., Spicer L.J., Spicer M.T. High-fat diets promote insulin resistance through cytokine gene expression in growing female rats. J. Nutr. Biochem. 2008, 19:505-513.
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 505-513
    • Flanagan, A.M.1    Brown, J.L.2    Santiago, C.A.3    Aad, P.Y.4    Spicer, L.J.5    Spicer, M.T.6
  • 26
    • 41549087566 scopus 로고    scopus 로고
    • Adiponectin and resistin response in the onset of obesity in male and female rats
    • Ribot J., Rodríguez A.M., Rodríguez E., Palou A. Adiponectin and resistin response in the onset of obesity in male and female rats. Obesity 2008, 16:723-730.
    • (2008) Obesity , vol.16 , pp. 723-730
    • Ribot, J.1    Rodríguez, A.M.2    Rodríguez, E.3    Palou, A.4
  • 27
    • 84904264999 scopus 로고    scopus 로고
    • Potential for primary prevention of Alzheimer's disease: an analysis of population-based data
    • Norton S., Matthews F.E., Barnes D.E., Yaffe K., Brayne C. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. Lancet Neurol. 2014, 13:788-794.
    • (2014) Lancet Neurol. , vol.13 , pp. 788-794
    • Norton, S.1    Matthews, F.E.2    Barnes, D.E.3    Yaffe, K.4    Brayne, C.5
  • 28
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetes-evidence reviewed
    • De la Monte S.M., Wands J.R. Alzheimer's disease is type 3 diabetes-evidence reviewed. J. Diabetes Sci. Technol. 2008, 2:1101-1113.
    • (2008) J. Diabetes Sci. Technol. , vol.2 , pp. 1101-1113
    • De la Monte, S.M.1    Wands, J.R.2
  • 29
    • 84908542203 scopus 로고    scopus 로고
    • IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity
    • White M.F. IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity. Diabetes Obes. Metab. 2014, 16(Suppl. 1):4-15.
    • (2014) Diabetes Obes. Metab. , vol.16 , pp. 4-15
    • White, M.F.1
  • 30
    • 80053624120 scopus 로고    scopus 로고
    • Brain insulin signalling: a key component of cognitive processes and a potential basis for cognitive impairment in type 2 diabetes
    • McNay E.C., Recknagel A.K. Brain insulin signalling: a key component of cognitive processes and a potential basis for cognitive impairment in type 2 diabetes. Neurobiol. Learn. Mem. 2011, 96:432-442.
    • (2011) Neurobiol. Learn. Mem. , vol.96 , pp. 432-442
    • McNay, E.C.1    Recknagel, A.K.2
  • 34
    • 84887076229 scopus 로고    scopus 로고
    • Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats
    • M.F.C.A.L.W.P.G.Q.C.K.K.M.J.S.P.O.P.
    • Castro G., M.F.C.A., L.W., P.G.Q., C.K.K., M.J.S., P.O.P. Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats. FEBS Open Bio 2013, 3:443-449.
    • (2013) FEBS Open Bio , vol.3 , pp. 443-449
    • Castro, G.1
  • 35
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: molecular targets of insulin resistance
    • Pessin J.E., Saltiel A.R. Signaling pathways in insulin action: molecular targets of insulin resistance. J. Clin. Invest. 2000, 106:165-169.
    • (2000) J. Clin. Invest. , vol.106 , pp. 165-169
    • Pessin, J.E.1    Saltiel, A.R.2
  • 36
    • 79960896430 scopus 로고    scopus 로고
    • Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
    • Liu Y., Liu F., Grundke-Iqbal I., Iqbal K., Gong C.X. Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J. Pathol. 2011, 225:54-62.
    • (2011) J. Pathol. , vol.225 , pp. 54-62
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 37
    • 28444466516 scopus 로고    scopus 로고
    • High-fat diets, insulin resistance and declining cognitive function
    • Greenwood C.E., Winocur G. High-fat diets, insulin resistance and declining cognitive function. Neurobiol. Aging 2005, 26(Suppl. 1):42-45.
    • (2005) Neurobiol. Aging , vol.26 , pp. 42-45
    • Greenwood, C.E.1    Winocur, G.2
  • 38
    • 71349085957 scopus 로고    scopus 로고
    • Defects in IGF-receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-and insulin signalling
    • Moloney A.M., Griffin R.J., Timmons S., O'Connor R., Ravid R., O'Neill C. Defects in IGF-receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-and insulin signalling. Neurobiol. Aging 2010, 31:224-243.
    • (2010) Neurobiol. Aging , vol.31 , pp. 224-243
    • Moloney, A.M.1    Griffin, R.J.2    Timmons, S.3    O'Connor, R.4    Ravid, R.5    O'Neill, C.6
  • 39
    • 84942193634 scopus 로고    scopus 로고
    • Naringin improves neuronal insulin signalling, brain mitochondrial function, and cognitive function in high-fat diet-induced obese mice
    • Wang D., Yan J., Chen J., Wu W., Zhu X., Wang Y. Naringin improves neuronal insulin signalling, brain mitochondrial function, and cognitive function in high-fat diet-induced obese mice. Cell. Mol. Neurobiol. 2015, 35:1061-1071.
    • (2015) Cell. Mol. Neurobiol. , vol.35 , pp. 1061-1071
    • Wang, D.1    Yan, J.2    Chen, J.3    Wu, W.4    Zhu, X.5    Wang, Y.6
  • 41
    • 33746238205 scopus 로고    scopus 로고
    • Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease
    • De la Monte S.M., Wands J.R. Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease. J. Alzheimers Dis. 2006, 9:167-181.
    • (2006) J. Alzheimers Dis. , vol.9 , pp. 167-181
    • De la Monte, S.M.1    Wands, J.R.2
  • 42
    • 33748478598 scopus 로고    scopus 로고
    • Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain
    • Soscia S.J., Tong M., Xu X.J., Cohen A.C., Chu J., Wands J.R., de la Monte S.M. Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain. Cell. Mol. Life Sci. 2006, 63:2039-2056.
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 2039-2056
    • Soscia, S.J.1    Tong, M.2    Xu, X.J.3    Cohen, A.C.4    Chu, J.5    Wands, J.R.6    de la Monte, S.M.7
  • 43
    • 81855164838 scopus 로고    scopus 로고
    • Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions
    • Yao J., Rettberg J.R., Klosinski L.P., Cadenas E., Brinton R.D. Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. Mol. Asp. Med. 2011, 32:247-257.
    • (2011) Mol. Asp. Med. , vol.32 , pp. 247-257
    • Yao, J.1    Rettberg, J.R.2    Klosinski, L.P.3    Cadenas, E.4    Brinton, R.D.5
  • 45
    • 77954981010 scopus 로고    scopus 로고
    • The effects of a high-energy diet on hippocampal function and blood-brain barrier integrity in the rat
    • Kanoski S.E., Zhang Y., Zheng W., Davidson T.L. The effects of a high-energy diet on hippocampal function and blood-brain barrier integrity in the rat. J. Alzheimers Dis. 2010, 21:207-219.
    • (2010) J. Alzheimers Dis. , vol.21 , pp. 207-219
    • Kanoski, S.E.1    Zhang, Y.2    Zheng, W.3    Davidson, T.L.4
  • 46
    • 0037458584 scopus 로고    scopus 로고
    • Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase
    • Ikemoto A., Bole D.G., Ueda T. Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. J. Biol. Chem. 2003, 278:5929-5940.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5929-5940
    • Ikemoto, A.1    Bole, D.G.2    Ueda, T.3
  • 47
    • 33745920510 scopus 로고    scopus 로고
    • Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease
    • Kirvell S.L., Esiri M., Francis P.T. Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease. J. Neurochem. 2006, 98:939-950.
    • (2006) J. Neurochem. , vol.98 , pp. 939-950
    • Kirvell, S.L.1    Esiri, M.2    Francis, P.T.3
  • 48
    • 67449116585 scopus 로고    scopus 로고
    • Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons
    • Lund T.M., Risa O., Sonnewald U., Schousboe A., Waagepetersen H.S. Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons. J. Neurochem. 2009, 110:80-91.
    • (2009) J. Neurochem. , vol.110 , pp. 80-91
    • Lund, T.M.1    Risa, O.2    Sonnewald, U.3    Schousboe, A.4    Waagepetersen, H.S.5
  • 49
    • 84938739658 scopus 로고    scopus 로고
    • The metabolic impact of β-hydroxybutyrate on neurotransmission: reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity
    • Lund T.M., Ploug K.B., Iversen A., Jensen A.A., Jansen-Olesen I. The metabolic impact of β-hydroxybutyrate on neurotransmission: reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity. J. Neurochem. 2014, 10.1111/jnc.12975.
    • (2014) J. Neurochem.
    • Lund, T.M.1    Ploug, K.B.2    Iversen, A.3    Jensen, A.A.4    Jansen-Olesen, I.5
  • 50
    • 62749126684 scopus 로고    scopus 로고
    • Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance
    • Padmalayam I., Hasham S., Saxena U., Pillarisetti S. Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance. Diabetes 2009, 58:600-608.
    • (2009) Diabetes , vol.58 , pp. 600-608
    • Padmalayam, I.1    Hasham, S.2    Saxena, U.3    Pillarisetti, S.4
  • 51
    • 84895072006 scopus 로고    scopus 로고
    • Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study
    • Sancheti H., Kanamori K., Patil I., Díaz B.R., Ross B.D., Cadenas E. Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study. J. Cereb. Blood Flow Metab. 2014, 34:288-296.
    • (2014) J. Cereb. Blood Flow Metab. , vol.34 , pp. 288-296
    • Sancheti, H.1    Kanamori, K.2    Patil, I.3    Díaz, B.R.4    Ross, B.D.5    Cadenas, E.6
  • 53
    • 84935885840 scopus 로고    scopus 로고
    • Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function
    • Hertz L., Chen Y., Waagepetersen H.S. Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function. J. Neurochem. 2015, 10.1111/jnc.13107.
    • (2015) J. Neurochem.
    • Hertz, L.1    Chen, Y.2    Waagepetersen, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.