-
1
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
Ohgaki H, Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol (2007) 170:1445-53. doi:10.2353/ajpath.2007.070011
-
(2007)
Am J Pathol
, vol.170
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med (2005) 352:987-96. doi:10.1056/NEJMoa043330
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
3
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol (2009) 10:459-66. doi:10.1016/S1470-2045(09)70025-7
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
-
4
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature (2009) 462:739-44. doi:10.1038/nature08617
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
5
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature (2008) 455:1061-8. doi:10.1038/nature07385
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
6
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, et al. An integrated genomic analysis of human glioblastoma multiforme. Science (2008) 321:1807-12. doi:10.1126/science.1164382
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
7
-
-
0033520476
-
The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase
-
Geisbrecht BV, Liang X, Morrell JC, Schulz H, Gould SJ. The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. J Biol Chem (1999) 274:25814-20. doi:10.1074/jbc.274.36.25814
-
(1999)
J Biol Chem
, vol.274
, pp. 25814-25820
-
-
Geisbrecht, B.V.1
Liang, X.2
Morrell, J.C.3
Schulz, H.4
Gould, S.J.5
-
8
-
-
79958126696
-
A tale of two subunits: how the neomorphic R132H IDH1 mutation enhances production of alphaHG
-
Pietrak B, Zhao H, Qi H, Quinn C, Gao E, Boyer JG, et al. A tale of two subunits: how the neomorphic R132H IDH1 mutation enhances production of alphaHG. Biochemistry (2011) 50:4804-12. doi:10.1021/bi200499m
-
(2011)
Biochemistry
, vol.50
, pp. 4804-4812
-
-
Pietrak, B.1
Zhao, H.2
Qi, H.3
Quinn, C.4
Gao, E.5
Boyer, J.G.6
-
9
-
-
84906491826
-
D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma
-
Pusch S, Schweizer L, Beck AC, Lehmler JM, Weissert S, Balss J, et al. D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma. Acta Neuropathol Commun (2014) 2:19. doi:10.1186/2051-5960-2-19
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 19
-
-
Pusch, S.1
Schweizer, L.2
Beck, A.C.3
Lehmler, J.M.4
Weissert, S.5
Balss, J.6
-
10
-
-
84873600673
-
From genomics to the clinic: biological and translational insights of mutant IDH1/2 in glioma
-
Dunn GP, Andronesi OC, Cahill DP. From genomics to the clinic: biological and translational insights of mutant IDH1/2 in glioma. Neurosurg Focus (2013) 34:E2. doi:10.3171/2012.12.FOCUS12355
-
(2013)
Neurosurg Focus
, vol.34
-
-
Dunn, G.P.1
Andronesi, O.C.2
Cahill, D.P.3
-
11
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol (2008) 116:597-602. doi:10.1007/s00401-008-0455-2
-
(2008)
Acta Neuropathol
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
von Deimling, A.6
-
12
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med (2009) 361:1058-66. doi:10.1056/NEJMoa0903840
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
Chen, K.6
-
13
-
-
77957192661
-
Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value
-
Abbas S, Lugthart S, Kavelaars FG, Schelen A, Koenders JE, Zeilemaker A, et al. Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value. Blood (2010) 116:2122-6. doi:10.1182/blood-2009-11-250878
-
(2010)
Blood
, vol.116
, pp. 2122-2126
-
-
Abbas, S.1
Lugthart, S.2
Kavelaars, F.G.3
Schelen, A.4
Koenders, J.E.5
Zeilemaker, A.6
-
14
-
-
77952426827
-
Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms
-
Kosmider O, Gelsi-Boyer V, Slama L, Dreyfus F, Beyne-Rauzy O, Quesnel B, et al. Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms. Leukemia (2010) 24:1094-6. doi:10.1038/leu.2010.52
-
(2010)
Leukemia
, vol.24
, pp. 1094-1096
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Slama, L.3
Dreyfus, F.4
Beyne-Rauzy, O.5
Quesnel, B.6
-
15
-
-
84879418850
-
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
-
Wang P, Dong Q, Zhang C, Kuan PF, Liu Y, Jeck WR, et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2013) 32:3091-100. doi:10.1038/onc.2012.315
-
(2013)
Oncogene
, vol.32
, pp. 3091-3100
-
-
Wang, P.1
Dong, Q.2
Zhang, C.3
Kuan, P.F.4
Liu, Y.5
Jeck, W.R.6
-
16
-
-
79958226901
-
IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
-
Amary MF, Bacsi K, Maggiani F, Damato S, Halai D, Berisha F, et al. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours. J Pathol (2011) 224:334-43. doi:10.1002/path.2913
-
(2011)
J Pathol
, vol.224
, pp. 334-343
-
-
Amary, M.F.1
Bacsi, K.2
Maggiani, F.3
Damato, S.4
Halai, D.5
Berisha, F.6
-
17
-
-
82255183051
-
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
-
Amary MF, Damato S, Halai D, Eskandarpour M, Berisha F, Bonar F, et al. Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat Genet (2011) 43:1262-5. doi:10.1038/ng.994
-
(2011)
Nat Genet
, vol.43
, pp. 1262-1265
-
-
Amary, M.F.1
Damato, S.2
Halai, D.3
Eskandarpour, M.4
Berisha, F.5
Bonar, F.6
-
18
-
-
78650018623
-
The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations
-
von Deimling A, Korshunov A, Hartmann C. The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations. Brain Pathol (2011) 21:74-87. doi:10.1111/j.1750-3639.2010.00454.x
-
(2011)
Brain Pathol
, vol.21
, pp. 74-87
-
-
von Deimling, A.1
Korshunov, A.2
Hartmann, C.3
-
19
-
-
78049359978
-
A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples
-
Setty P, Hammes J, Rothamel T, Vladimirova V, Kramm CM, Pietsch T, et al. A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples. J Mol Diagn (2010) 12:750-6. doi:10.2353/jmoldx.2010.090237
-
(2010)
J Mol Diagn
, vol.12
, pp. 750-756
-
-
Setty, P.1
Hammes, J.2
Rothamel, T.3
Vladimirova, V.4
Kramm, C.M.5
Pietsch, T.6
-
20
-
-
75949103649
-
PCR-and restriction endonuclease-based detection of IDH1 mutations
-
Meyer J, Pusch S, Balss J, Capper D, Mueller W, Christians A, et al. PCR-and restriction endonuclease-based detection of IDH1 mutations. Brain Pathol (2010) 20:298-300. doi:10.1111/j.1750-3639.2009.00327.x
-
(2010)
Brain Pathol
, vol.20
, pp. 298-300
-
-
Meyer, J.1
Pusch, S.2
Balss, J.3
Capper, D.4
Mueller, W.5
Christians, A.6
-
21
-
-
78649585883
-
COLD PCR HRM: a highly sensitive detection method for IDH1 mutations
-
Boisselier B, Marie Y, Labussiere M, Ciccarino P, Desestret V, Wang X, et al. COLD PCR HRM: a highly sensitive detection method for IDH1 mutations. Hum Mutat (2010) 31:1360-5. doi:10.1002/humu.21365
-
(2010)
Hum Mutat
, vol.31
, pp. 1360-1365
-
-
Boisselier, B.1
Marie, Y.2
Labussiere, M.3
Ciccarino, P.4
Desestret, V.5
Wang, X.6
-
22
-
-
77954566882
-
Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine
-
Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBO Mol Med (2010) 2:146-58. doi:10.1002/emmm.201000070
-
(2010)
EMBO Mol Med
, vol.2
, pp. 146-158
-
-
Dias-Santagata, D.1
Akhavanfard, S.2
David, S.S.3
Vernovsky, K.4
Kuhlmann, G.5
Boisvert, S.L.6
-
23
-
-
70849116358
-
Profiling critical cancer gene mutations in clinical tumor samples
-
MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, et al. Profiling critical cancer gene mutations in clinical tumor samples. PLoS One (2009) 4:e7887. doi:10.1371/journal.pone.0007887
-
(2009)
PLoS One
, vol.4
-
-
MacConaill, L.E.1
Campbell, C.D.2
Kehoe, S.M.3
Bass, A.J.4
Hatton, C.5
Niu, L.6
-
24
-
-
84871250894
-
Detection of IDH1 mutation in the plasma of patients with glioma
-
Boisselier B, Gallego Perez-Larraya J, Rossetto M, Labussiere M, Ciccarino P, Marie Y, et al. Detection of IDH1 mutation in the plasma of patients with glioma. Neurology (2012) 79:1693-8. doi:10.1212/WNL.0b013e31826e9b0a
-
(2012)
Neurology
, vol.79
, pp. 1693-1698
-
-
Boisselier, B.1
Gallego Perez-Larraya, J.2
Rossetto, M.3
Labussiere, M.4
Ciccarino, P.5
Marie, Y.6
-
25
-
-
84902120217
-
Comparative examination of various PCR-based methods for DNMT3A and IDH1/2 mutations identification in acute myeloid leukemia
-
Berenstein R, Blau IW, Kar A, Cay R, Sindram A, Seide C, et al. Comparative examination of various PCR-based methods for DNMT3A and IDH1/2 mutations identification in acute myeloid leukemia. J Exp Clin Cancer Res (2014) 33:44. doi:10.1186/1756-9966-33-44
-
(2014)
J Exp Clin Cancer Res
, vol.33
, pp. 44
-
-
Berenstein, R.1
Blau, I.W.2
Kar, A.3
Cay, R.4
Sindram, A.5
Seide, C.6
-
26
-
-
84921670101
-
A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma
-
Catteau A, Girardi H, Monville F, Poggionovo C, Carpentier S, Frayssinet V, et al. A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma. Acta Neuropathol Commun (2014) 2:58. doi:10.1186/2051-5960-2-58
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 58
-
-
Catteau, A.1
Girardi, H.2
Monville, F.3
Poggionovo, C.4
Carpentier, S.5
Frayssinet, V.6
-
27
-
-
79451475068
-
Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology
-
Capper D, Reuss D, Schittenhelm J, Hartmann C, Bremer J, Sahm F, et al. Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. Acta Neuropathol (2011) 121:241-52. doi:10.1007/s00401-010-0770-2
-
(2011)
Acta Neuropathol
, vol.121
, pp. 241-252
-
-
Capper, D.1
Reuss, D.2
Schittenhelm, J.3
Hartmann, C.4
Bremer, J.5
Sahm, F.6
-
28
-
-
80052780994
-
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing
-
Takano S, Tian W, Matsuda M, Yamamoto T, Ishikawa E, Kaneko MK, et al. Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing. Brain Tumor Pathol (2011) 28:115-23. doi:10.1007/s10014-011-0023-7
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 115-123
-
-
Takano, S.1
Tian, W.2
Matsuda, M.3
Yamamoto, T.4
Ishikawa, E.5
Kaneko, M.K.6
-
29
-
-
79251601011
-
A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53
-
Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Cosper AK, Dias-Santagata D, et al. A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53. J Neuropathol Exp Neurol (2011) 70:110-5. doi:10.1097/NEN.0b013e31820565f9
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 110-115
-
-
Camelo-Piragua, S.1
Jansen, M.2
Ganguly, A.3
Kim, J.C.4
Cosper, A.K.5
Dias-Santagata, D.6
-
30
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell (2010) 17:225-34. doi:10.1016/j.ccr.2010.01.020
-
(2010)
Cancer Cell
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
Abdel-Wahab, O.4
Bennett, B.D.5
Coller, H.A.6
-
31
-
-
84859554794
-
2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size
-
Capper D, Simon M, Langhans CD, Okun JG, Tonn JC, Weller M, et al. 2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size. Int J Cancer (2012) 131:766-8. doi:10.1002/ijc.26425
-
(2012)
Int J Cancer
, vol.131
, pp. 766-768
-
-
Capper, D.1
Simon, M.2
Langhans, C.D.3
Okun, J.G.4
Tonn, J.C.5
Weller, M.6
-
32
-
-
84865291187
-
Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma
-
Carrillo JA, Lai A, Nghiemphu PL, Kim HJ, Phillips HS, Kharbanda S, et al. Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma. AJNR Am J Neuroradiol (2012) 33:1349-55. doi:10.3174/ajnr. A2950
-
(2012)
AJNR Am J Neuroradiol
, vol.33
, pp. 1349-1355
-
-
Carrillo, J.A.1
Lai, A.2
Nghiemphu, P.L.3
Kim, H.J.4
Phillips, H.S.5
Kharbanda, S.6
-
33
-
-
84858603856
-
Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy
-
Pope WB, Prins RM, Albert Thomas M, Nagarajan R, Yen KE, Bittinger MA, et al. Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. J Neurooncol (2012) 107:197-205. doi:10.1007/s11060-011-0737-8
-
(2012)
J Neurooncol
, vol.107
, pp. 197-205
-
-
Pope, W.B.1
Prins, R.M.2
Albert Thomas, M.3
Nagarajan, R.4
Yen, K.E.5
Bittinger, M.A.6
-
34
-
-
84862776826
-
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
-
Choi C, Ganji SK, DeBerardinis RJ, Hatanpaa KJ, Rakheja D, Kovacs Z, et al. 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas. Nat Med (2012) 18:624-9. doi:10.1038/nm.2682
-
(2012)
Nat Med
, vol.18
, pp. 624-629
-
-
Choi, C.1
Ganji, S.K.2
DeBerardinis, R.J.3
Hatanpaa, K.J.4
Rakheja, D.5
Kovacs, Z.6
-
35
-
-
84855710482
-
Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy
-
Andronesi OC, Kim GS, Gerstner E, Batchelor T, Tzika AA, Fantin VR, et al. Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. Sci Transl Med (2012) 4:116ra114. doi:10.1126/scitranslmed.3002693
-
(2012)
Sci Transl Med
, vol.4
-
-
Andronesi, O.C.1
Kim, G.S.2
Gerstner, E.3
Batchelor, T.4
Tzika, A.A.5
Fantin, V.R.6
-
36
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
-
Ichimura K, Pearson DM, Kocialkowski S, Backlund LM, Chan R, Jones DT, et al. IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Neuro Oncol (2009) 11:341-7. doi:10.1215/15228517-2009-025
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
Backlund, L.M.4
Chan, R.5
Jones, D.T.6
-
37
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S, Idbaih A, Laffaire J, Ducray F, et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol (2009) 27:4150-4. doi:10.1200/JCO.2009.21.9832
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
Idbaih, A.4
Laffaire, J.5
Ducray, F.6
-
38
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med (2009) 360:765-73. doi:10.1056/NEJMoa0808710
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
-
39
-
-
77149152775
-
Segregation of non-p. R132H mutations in IDH1 in distinct molecular subtypes of glioma
-
Gravendeel LA, Kloosterhof NK, Bralten LB, van Marion R, Dubbink HJ, Dinjens W, et al. Segregation of non-p. R132H mutations in IDH1 in distinct molecular subtypes of glioma. Hum Mutat (2010) 31:E1186-99. doi:10.1002/humu.21201
-
(2010)
Hum Mutat
, vol.31
, pp. E1186-E1199
-
-
Gravendeel, L.A.1
Kloosterhof, N.K.2
Bralten, L.B.3
van Marion, R.4
Dubbink, H.J.5
Dinjens, W.6
-
40
-
-
77953351926
-
All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2
-
Labussiere M, Idbaih A, Wang XW, Marie Y, Boisselier B, Falet C, et al. All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2. Neurology (2010) 74:1886-90. doi:10.1212/WNL.0b013e3181e1cf3a
-
(2010)
Neurology
, vol.74
, pp. 1886-1890
-
-
Labussiere, M.1
Idbaih, A.2
Wang, X.W.3
Marie, Y.4
Boisselier, B.5
Falet, C.6
-
41
-
-
77649122144
-
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group
-
van den Bent MJ, Dubbink HJ, Marie Y, Brandes AA, Taphoorn MJ, Wesseling P, et al. IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. Clin Cancer Res (2010) 16:1597-604. doi:10.1158/1078-0432.CCR-09-2902
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1597-1604
-
-
van den Bent, M.J.1
Dubbink, H.J.2
Marie, Y.3
Brandes, A.A.4
Taphoorn, M.J.5
Wesseling, P.6
-
42
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol (2009) 27:5874-80. doi:10.1200/JCO.2009.23.6497
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
Stoffels, M.4
Felsberg, J.5
Stockhammer, F.6
-
43
-
-
73349108806
-
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide
-
Dubbink HJ, Taal W, van Marion R, Kros JM, van Heuvel I, Bromberg JE, et al. IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. Neurology (2009) 73:1792-5. doi:10.1212/WNL.0b013e3181c34ace
-
(2009)
Neurology
, vol.73
, pp. 1792-1795
-
-
Dubbink, H.J.1
Taal, W.2
van Marion, R.3
Kros, J.M.4
van Heuvel, I.5
Bromberg, J.E.6
-
44
-
-
78651067051
-
Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis
-
Metellus P, Coulibaly B, Colin C, de Paula AM, Vasiljevic A, Taieb D, et al. Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis. Acta Neuropathol (2010) 120:719-29. doi:10.1007/s00401-010-0777-8
-
(2010)
Acta Neuropathol
, vol.120
, pp. 719-729
-
-
Metellus, P.1
Coulibaly, B.2
Colin, C.3
de Paula, A.M.4
Vasiljevic, A.5
Taieb, D.6
-
45
-
-
78650226575
-
Molecular classification of low-grade diffuse gliomas
-
Kim YH, Nobusawa S, Mittelbronn M, Paulus W, Brokinkel B, Keyvani K, et al. Molecular classification of low-grade diffuse gliomas. Am J Pathol (2010) 177:2708-14. doi:10.2353/ajpath.2010.100680
-
(2010)
Am J Pathol
, vol.177
, pp. 2708-2714
-
-
Kim, Y.H.1
Nobusawa, S.2
Mittelbronn, M.3
Paulus, W.4
Brokinkel, B.5
Keyvani, K.6
-
46
-
-
78149249554
-
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
-
Houillier C, Wang X, Kaloshi G, Mokhtari K, Guillevin R, Laffaire J, et al. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology (2010) 75:1560-6. doi:10.1212/WNL.0b013e3181f96282
-
(2010)
Neurology
, vol.75
, pp. 1560-1566
-
-
Houillier, C.1
Wang, X.2
Kaloshi, G.3
Mokhtari, K.4
Guillevin, R.5
Laffaire, J.6
-
47
-
-
79960315686
-
Molecular markers in low-grade gliomas: predictive or prognostic?
-
Hartmann C, Hentschel B, Tatagiba M, Schramm J, Schnell O, Seidel C, et al. Molecular markers in low-grade gliomas: predictive or prognostic? Clin Cancer Res (2011) 17:4588-99. doi:10.1158/1078-0432.CCR-10-3194
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4588-4599
-
-
Hartmann, C.1
Hentschel, B.2
Tatagiba, M.3
Schramm, J.4
Schnell, O.5
Seidel, C.6
-
48
-
-
84868611367
-
Mutant IDH1 is required for IDH1 mutated tumor cell growth
-
Jin G, Pirozzi CJ, Chen LH, Lopez GY, Duncan CG, Feng J, et al. Mutant IDH1 is required for IDH1 mutated tumor cell growth. Oncotarget (2012) 3:774-82. doi:10.18632/oncotarget.577
-
(2012)
Oncotarget
, vol.3
, pp. 774-782
-
-
Jin, G.1
Pirozzi, C.J.2
Chen, L.H.3
Lopez, G.Y.4
Duncan, C.G.5
Feng, J.6
-
49
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell (2007) 128:683-92. doi:10.1016/j.cell.2007.01.029
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
50
-
-
84877923019
-
Molecular subtypes of glioma identified by genome-wide methylation profiling
-
Kloosterhof NK, de Rooi JJ, Kros M, Eilers PH, Sillevis Smitt PA, van den Bent MJ, et al. Molecular subtypes of glioma identified by genome-wide methylation profiling. Genes Chromosomes Cancer (2013) 52:665-74. doi:10.1002/gcc.22062
-
(2013)
Genes Chromosomes Cancer
, vol.52
, pp. 665-674
-
-
Kloosterhof, N.K.1
de Rooi, J.J.2
Kros, M.3
Eilers, P.H.4
Sillevis Smitt, P.A.5
van den Bent, M.J.6
-
51
-
-
33749039999
-
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
-
Cadieux B, Ching TT, VandenBerg SR, Costello JF. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res (2006) 66:8469-76. doi:10.1158/0008-5472.CAN-06-1547
-
(2006)
Cancer Res
, vol.66
, pp. 8469-8476
-
-
Cadieux, B.1
Ching, T.T.2
VandenBerg, S.R.3
Costello, J.F.4
-
52
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet (2007) 39:457-66. doi:10.1038/ng1990
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
-
53
-
-
84878106525
-
The good, the bad and the ugly: epigenetic mechanisms in glioblastoma
-
Caren H, Pollard SM, Beck S. The good, the bad and the ugly: epigenetic mechanisms in glioblastoma. Mol Aspects Med (2013) 34:849-62. doi:10.1016/j.mam.2012.06.007
-
(2013)
Mol Aspects Med
, vol.34
, pp. 849-862
-
-
Caren, H.1
Pollard, S.M.2
Beck, S.3
-
54
-
-
69949087520
-
A microarray-based DNA methylation study of glioblastoma multiforme
-
Martinez R, Martin-Subero JI, Rohde V, Kirsch M, Alaminos M, Fernandez AF, et al. A microarray-based DNA methylation study of glioblastoma multiforme. Epigenetics (2009) 4:255-64. doi:10.4161/epi.9130
-
(2009)
Epigenetics
, vol.4
, pp. 255-264
-
-
Martinez, R.1
Martin-Subero, J.I.2
Rohde, V.3
Kirsch, M.4
Alaminos, M.5
Fernandez, A.F.6
-
55
-
-
77951247981
-
Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas
-
Gotze S, Wolter M, Reifenberger G, Muller O, Sievers S. Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas. Int J Cancer (2010) 126:2584-93. doi:10.1002/ijc.24981
-
(2010)
Int J Cancer
, vol.126
, pp. 2584-2593
-
-
Gotze, S.1
Wolter, M.2
Reifenberger, G.3
Muller, O.4
Sievers, S.5
-
56
-
-
33846821916
-
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
Bruna A, Darken RS, Rojo F, Ocana A, Penuelas S, Arias A, et al. High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell (2007) 11:147-60. doi:10.1016/j.ccr.2006.11.023
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
Ocana, A.4
Penuelas, S.5
Arias, A.6
-
57
-
-
15744392240
-
Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas
-
Waha A, Guntner S, Huang TH, Yan PS, Arslan B, Pietsch T, et al. Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. Neoplasia (2005) 7:193-9. doi:10.1593/neo.04490
-
(2005)
Neoplasia
, vol.7
, pp. 193-199
-
-
Waha, A.1
Guntner, S.2
Huang, T.H.3
Yan, P.S.4
Arslan, B.5
Pietsch, T.6
-
58
-
-
34247892414
-
Reciprocal regulation of SOCS 1 and SOCS3 enhances resistance to ionizing radiation in glioblastoma multiforme
-
Zhou H, Miki R, Eeva M, Fike FM, Seligson D, Yang L, et al. Reciprocal regulation of SOCS 1 and SOCS3 enhances resistance to ionizing radiation in glioblastoma multiforme. Clin Cancer Res (2007) 13:2344-53. doi:10.1158/1078-0432.CCR-06-2303
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2344-2353
-
-
Zhou, H.1
Miki, R.2
Eeva, M.3
Fike, F.M.4
Seligson, D.5
Yang, L.6
-
59
-
-
47749133381
-
Copy number alterations of the polycomb gene BMI1 in gliomas
-
Hayry V, Tanner M, Blom T, Tynninen O, Roselli A, Ollikainen M, et al. Copy number alterations of the polycomb gene BMI1 in gliomas. Acta Neuropathol (2008) 116:97-102. doi:10.1007/s00401-008-0376-0
-
(2008)
Acta Neuropathol
, vol.116
, pp. 97-102
-
-
Hayry, V.1
Tanner, M.2
Blom, T.3
Tynninen, O.4
Roselli, A.5
Ollikainen, M.6
-
60
-
-
52249090461
-
Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas
-
Lucio-Eterovic AK, Cortez MA, Valera ET, Motta FJ, Queiroz RG, Machado HR, et al. Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas. BMC Cancer (2008) 8:243. doi:10.1186/1471-2407-8-243
-
(2008)
BMC Cancer
, vol.8
, pp. 243
-
-
Lucio-Eterovic, A.K.1
Cortez, M.A.2
Valera, E.T.3
Motta, F.J.4
Queiroz, R.G.5
Machado, H.R.6
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