-
1
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008;321(5897):1807-1812.
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
2
-
-
58349111311
-
IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors
-
Bleeker FE, Lamba S, Leenstra S, et al. IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat. 2009;30(1):7-11.
-
(2009)
Hum Mutat
, vol.30
, Issue.1
, pp. 7-11
-
-
Bleeker, F.E.1
Lamba, S.2
Leenstra, S.3
-
3
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, ParsonsDW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360(8):765-773.
-
(2009)
N Engl J Med
, vol.360
, Issue.8
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
4
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
-
Zhao S, Lin Y, Xu W, et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science. 2009;324(5924):261-265.
-
(2009)
Science
, vol.324
, Issue.5924
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
-
5
-
-
77149134353
-
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
-
Gross S, Cairns RA, Minden MD, et al. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med. 2010;207(2):339-344.
-
(2010)
J Exp Med
, vol.207
, Issue.2
, pp. 339-344
-
-
Gross, S.1
Cairns, R.A.2
Minden, M.D.3
-
6
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 2010;17(3):225-234.
-
(2010)
Cancer Cell
, vol.17
, Issue.3
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
-
7
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361(11):1058- 1066.
-
(2009)
N Engl J Med
, vol.361
, Issue.11
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
-
8
-
-
77950968519
-
Distinct clinical and biological characteristics in adult acute myeloid leukemia bearing isocitrate dehydrogenase 1 (IDH1) mutation
-
Chou WC, Hou HA, Chen CY, et al. Distinct clinical and biological characteristics in adult acute myeloid leukemia bearing isocitrate dehydrogenase 1 (IDH1) mutation. Blood. 2010;115(14):2749-2754.
-
(2010)
Blood
, vol.115
, Issue.14
, pp. 2749-2754
-
-
Chou, W.C.1
Hou, H.A.2
Chen, C.Y.3
-
9
-
-
54349092877
-
Monosomal karyotype in acute myeloid leukemia: A better indicator of poor prognosis than a complex karyotype
-
Breems DA, Van Putten WL, De Greef GE, et al. Monosomal karyotype in acute myeloid leukemia: a better indicator of poor prognosis than a complex karyotype. J Clin Oncol. 2008;26(29):4791-4797.
-
(2008)
J Clin Oncol
, vol.26
, Issue.29
, pp. 4791-4797
-
-
Breems, D.A.1
Van Putten, W.L.2
De Greef, G.E.3
-
10
-
-
0842328518
-
Second hit mutations in the RTK/RAS signaling pathway in acute myeloid leukemia with inv(16)
-
Valk PJM, Bowen DT, Frew ME, Goodeve AC, Löwenberg B, Reilly JT. Second hit mutations in the RTK/RAS signalling pathway in acute myeloid leukaemia and inv(16). Haematologica. 2004;89(01):106. (Pubitemid 38165863)
-
(2004)
Haematologica
, vol.89
, Issue.1
, pp. 106
-
-
Valk, P.J.M.1
Bowen, D.T.2
Frew, M.E.3
Goodeve, A.C.4
Lowenberg, B.5
Reilly, J.T.6
-
11
-
-
0037591396
-
Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML
-
van Waalwijk van Doorn-Khosrovani SB, Erpelinck C, Meijer J, et al. Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML. Hematol J. 2003;4(1):31-40.
-
(2003)
Hematol J
, vol.4
, Issue.1
, pp. 31-40
-
-
Van Waalwijk Van Doorn-Khosrovani, S.B.1
Erpelinck, C.2
Meijer, J.3
-
12
-
-
0038170400
-
Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias
-
Care RS, Valk PJ, Goodeve AC, et al. Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias. Br J Haematol. 2003;121(5):775-777.
-
(2003)
Br J Haematol
, vol.121
, Issue.5
, pp. 775-777
-
-
Care, R.S.1
Valk, P.J.2
Goodeve, A.C.3
-
13
-
-
28444446313
-
Mutations in nucleophosmin NPM1 in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
Verhaak RG, Goudswaard CS, van Putten W, et al. Mutations in nucleophosmin NPM1 in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood. 2005;106(12):3747-3754.
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3747-3754
-
-
Verhaak, R.G.1
Goudswaard, C.S.2
Van Putten, W.3
-
14
-
-
75449119103
-
Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms
-
Green A, Beer P. Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms. N Engl J Med. 2010;362(4):369-370.
-
(2010)
N Engl J Med
, vol.362
, Issue.4
, pp. 369-370
-
-
Green, A.1
Beer, P.2
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