-
1
-
-
79953287708
-
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
-
Bralten LB, Kloosterhof NK, Balvers R, Sacchetti A, Lapre L, Lamfers M, Leenstra S, de Jonge H, Kros JM, Jansen EE, Struys EA, Jakobs C, Salomons GS, Diks SH, Peppelenbosch M, Kremer A, Hoogenraad CC, Smitt PA, French PJ. 2011. IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo. Ann Neurol 69:455-463.
-
(2011)
Ann Neurol
, vol.69
, pp. 455-463
-
-
Bralten, L.B.1
Kloosterhof, N.K.2
Balvers, R.3
Sacchetti, A.4
Lapre, L.5
Lamfers, M.6
Leenstra, S.7
de Jonge, H.8
Kros, J.M.9
Jansen, E.E.10
Struys, E.A.11
Jakobs, C.12
Salomons, G.S.13
Diks, S.H.14
Peppelenbosch, M.15
Kremer, A.16
Hoogenraad, C.C.17
Smitt, P.A.18
French, P.J.19
-
2
-
-
84867320257
-
Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas
-
Chou AP, Chowdhury R, Li S, Chen W, Kim AJ, Piccioni DE, Selfridge JM, Mody RR, Chang S, Lalezari S, Lin J, Sanchez DE, Wilson RW, Garrett MC, Harry B, Mottahedeh J, Nghiemphu PL, Kornblum HI, Mischel PS, Prins RM, Yong WH, Cloughesy T, Nelson SF, Liau LM, Lai A. 2012. Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas. J Natl Cancer Inst 104:1458-1469.
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 1458-1469
-
-
Chou, A.P.1
Chowdhury, R.2
Li, S.3
Chen, W.4
Kim, A.J.5
Piccioni, D.E.6
Selfridge, J.M.7
Mody, R.R.8
Chang, S.9
Lalezari, S.10
Lin, J.11
Sanchez, D.E.12
Wilson, R.W.13
Garrett, M.C.14
Harry, B.15
Mottahedeh, J.16
Nghiemphu, P.L.17
Kornblum, H.I.18
Mischel, P.S.19
Prins, R.M.20
Yong, W.H.21
Cloughesy, T.22
Nelson, S.F.23
Liau, L.M.24
Lai, A.25
more..
-
3
-
-
79251470741
-
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma
-
Christensen BC, Smith AA, Zheng S, Koestler DC, Houseman EA, Marsit CJ, Wiemels JL, Nelson HH, Karagas MR, Wrensch MR, Kelsey KT, Wiencke JK. 2011. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst 103:143-153.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 143-153
-
-
Christensen, B.C.1
Smith, A.A.2
Zheng, S.3
Koestler, D.C.4
Houseman, E.A.5
Marsit, C.J.6
Wiemels, J.L.7
Nelson, H.H.8
Karagas, M.R.9
Wrensch, M.R.10
Kelsey, K.T.11
Wiencke, J.K.12
-
4
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD, Cantley LC, Thompson CB, Vander Heiden MG, Su SM. 2009. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462:739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
Fantin, V.R.7
Jang, H.G.8
Jin, S.9
Keenan, M.C.10
Marks, K.M.11
Prins, R.M.12
Ward, P.S.13
Yen, K.E.14
Liau, L.M.15
Rabinowitz, J.D.16
Cantley, L.C.17
Thompson, C.B.18
Vander Heiden, M.G.19
Su, S.M.20
more..
-
5
-
-
78649475003
-
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
-
Du P, Zhang X, Huang CC, Jafari N, Kibbe WA, Hou L, Lin SM. 2010. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics 11:587.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 587
-
-
Du, P.1
Zhang, X.2
Huang, C.C.3
Jafari, N.4
Kibbe, W.A.5
Hou, L.6
Lin, S.M.7
-
6
-
-
84873362485
-
Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951
-
Erdem-Eraslan L, Gravendeel LA, de Rooi J, Eilers PH, Idbaih A, Spliet WG, den Dunnen WF, Teepen JL, Wesseling P, Sillevis Smitt PA, Kros JM, Gorlia T, van den Bent MJ, French PJ. 2013. Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951. J Clin Oncol 31:328-336.
-
(2013)
J Clin Oncol
, vol.31
, pp. 328-336
-
-
Erdem-Eraslan, L.1
Gravendeel, L.A.2
De Rooi, J.3
Eilers, P.H.4
Idbaih, A.5
Spliet, W.G.6
Den Dunnen, W.F.7
Teepen, J.L.8
Wesseling, P.9
Sillevis Smitt, P.A.10
Kros, J.M.11
Gorlia, T.12
Van Den Bent, M.J.13
French, P.J.14
-
7
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. 2008. Epigenetics in cancer. N Engl J Med 358:1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
8
-
-
78650035002
-
DNA methylation in glioblastoma: Impact on gene expression and clinical outcome
-
Etcheverry A, Aubry M, de Tayrac M, Vauleon E, Boniface R, Guenot F, Saikali S, Hamlat A, Riffaud L, Menei P, Quillien V, Mosser J. 2010. DNA methylation in glioblastoma: Impact on gene expression and clinical outcome. BMC Genomics 11:701.
-
(2010)
BMC Genomics
, vol.11
, pp. 701
-
-
Etcheverry, A.1
Aubry, M.2
de Tayrac, M.3
Vauleon, E.4
Boniface, R.5
Guenot, F.6
Saikali, S.7
Hamlat, A.8
Riffaud, L.9
Menei, P.10
Quillien, V.11
Mosser, J.12
-
9
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, Choe SE, Fantin VR, Paietta E, Lowenberg B, Licht JD, Godley LA, Delwel R, Valk PJ, Thompson CB, Levine RL, Melnick A. 2010. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18:553-567.
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
Shih, A.6
Li, Y.7
Bhagwat, N.8
Vasanthakumar, A.9
Fernandez, H.F.10
Tallman, M.S.11
Sun, Z.12
Wolniak, K.13
Peeters, J.K.14
Liu, W.15
Choe, S.E.16
Fantin, V.R.17
Paietta, E.18
Lowenberg, B.19
Licht, J.D.20
Godley, L.A.21
Delwel, R.22
Valk, P.J.23
Thompson, C.B.24
Levine, R.L.25
Melnick, A.26
more..
-
10
-
-
29244472476
-
Gene expression profiles associated with treatment response in oligodendrogliomas
-
French PJ, Swagemakers SMA, Nagel JHA, Kouwenhoven MCM, Brouwer E, van der Spek P, Luider TM, Kros JM, van den Bent MJ, Sillevis Smitt PA. 2005. Gene expression profiles associated with treatment response in oligodendrogliomas. Cancer Res 65:11335-11344.
-
(2005)
Cancer Res
, vol.65
, pp. 11335-11344
-
-
French, P.J.1
Swagemakers, S.M.A.2
Nagel, J.H.A.3
Kouwenhoven, M.C.M.4
Brouwer, E.5
Van Der Spek, P.6
Luider, T.M.7
Kros, J.M.8
Van Den Bent, M.J.9
Sillevis Smitt, P.A.10
-
11
-
-
71549126830
-
Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology
-
Gravendeel LA, Kouwenhoven MC, Gevaert O, de Rooi JJ, Stubbs AP, Duijm JE, Daemen A, Bleeker FE, Bralten LB, Kloosterhof NK, De Moor B, Eilers PH, van der Spek PJ, Kros JM, Sillevis Smitt PA, van den Bent MJ, French PJ. 2009. Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology. Cancer Res 69:9065-9072.
-
(2009)
Cancer Res
, vol.69
, pp. 9065-9072
-
-
Gravendeel, L.A.1
Kouwenhoven, M.C.2
Gevaert, O.3
de Rooi, J.J.4
Stubbs, A.P.5
Duijm, J.E.6
Daemen, A.7
Bleeker, F.E.8
Bralten, L.B.9
Kloosterhof, N.K.10
De Moor, B.11
Eilers, P.H.12
Van Der Spek, P.J.13
Kros, J.M.14
Sillevis Smitt, P.A.15
Van Den Bent, M.J.16
French, P.J.17
-
12
-
-
77149152775
-
Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma
-
Gravendeel LA, Kloosterhof NK, Bralten LB, van Marion R, Dubbink HJ, Dinjens W, Bleeker FE, Hoogenraad CC, Michiels E, Kros JM, van den Bent M, Smitt PA, French PJ. 2010. Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma. Hum Mutat 31:E1186-E1199.
-
(2010)
Hum Mutat
, vol.31
-
-
Gravendeel, L.A.1
Kloosterhof, N.K.2
Bralten, L.B.3
Van Marion, R.4
Dubbink, H.J.5
Dinjens, W.6
Bleeker, F.E.7
Hoogenraad, C.C.8
Michiels, E.9
Kros, J.M.10
van den Bent, M.11
Smitt, P.A.12
French, P.J.13
-
13
-
-
77149134353
-
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
-
Gross S, Cairns RA, Minden MD, Driggers EM, Bittinger MA, Jang HG, Sasaki M, Jin S, Schenkein DP, Su SM, Dang L, Fantin VR, Mak TW. 2010. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med 207:339-344.
-
(2010)
J Exp Med
, vol.207
, pp. 339-344
-
-
Gross, S.1
Cairns, R.A.2
Minden, M.D.3
Driggers, E.M.4
Bittinger, M.A.5
Jang, H.G.6
Sasaki, M.7
Jin, S.8
Schenkein, D.P.9
Su, S.M.10
Dang, L.11
Fantin, V.R.12
Mak, T.W.13
-
14
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL. 2011. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333:1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
Sun, Y.11
Li, X.12
Dai, Q.13
Song, C.X.14
Zhang, K.15
He, C.16
Xu, G.L.17
-
15
-
-
81255179895
-
The CpG island methylator phenotype in colorectal cancer: Progress and problems
-
Hughes LA, Khalid-de Bakker CA, Smits KM, van den Brandt PA, Jonkers D, Ahuja N, Herman JG, Weijenberg MP, van Engeland M. 2012. The CpG island methylator phenotype in colorectal cancer: Progress and problems. Biochim Biophys Acta 1825:77-85.
-
(2012)
Biochim Biophys Acta
, vol.1825
, pp. 77-85
-
-
Hughes, L.A.1
Khalid-de Bakker, C.A.2
Smits, K.M.3
Van Den Brandt, P.A.4
Jonkers, D.5
Ahuja, N.6
Herman, J.G.7
Weijenberg, M.P.8
Van Engeland, M.9
-
16
-
-
79957905986
-
Molecular subclassification of diffuse gliomas: Seeing order in the chaos
-
Huse JT, Phillips HS, Brennan CW. 2011. Molecular subclassification of diffuse gliomas: Seeing order in the chaos. Glia 59:1190-1199.
-
(2011)
Glia
, vol.59
, pp. 1190-1199
-
-
Huse, J.T.1
Phillips, H.S.2
Brennan, C.W.3
-
17
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y. 2011. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333:1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
18
-
-
33845438621
-
Are clusters found in one dataset present in another dataset?
-
Kapp AV, Tibshirani R. 2007. Are clusters found in one dataset present in another dataset? Biostatistics 8:9-31.
-
(2007)
Biostatistics
, vol.8
, pp. 9-31
-
-
Kapp, A.V.1
Tibshirani, R.2
-
19
-
-
78650682939
-
Isocitrate dehydrogenase-1 mutations: A fundamentally new understanding of diffuse glioma?
-
Kloosterhof NK, Bralten LB, Dubbink HJ, French PJ, van den Bent MJ. 2011. Isocitrate dehydrogenase-1 mutations: A fundamentally new understanding of diffuse glioma? Lancet Oncol 12:83-91.
-
(2011)
Lancet Oncol
, vol.12
, pp. 83-91
-
-
Kloosterhof, N.K.1
Bralten, L.B.2
Dubbink, H.J.3
French, P.J.4
Van Den Bent, M.J.5
-
20
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG, Jr. 1971. Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson Jr, A.G.1
-
21
-
-
34249915554
-
Panel review of anaplastic oligodendroglioma from European Organization For Research and Treatment of Cancer Trial 26951: Assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome
-
Kros JM, Gorlia T, Kouwenhoven MC, Zheng PP, Collins VP, Figarella-Branger D, Giangaspero F, Giannini C, Mokhtari K, Mork SJ, Paetau A, Reifenberger G, van den Bent MJ. 2007. Panel review of anaplastic oligodendroglioma from European Organization For Research and Treatment of Cancer Trial 26951: Assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome. J Neuropathol Exp Neurol 66:545-551.
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 545-551
-
-
Kros, J.M.1
Gorlia, T.2
Kouwenhoven, M.C.3
Zheng, P.P.4
Collins, V.P.5
Figarella-Branger, D.6
Giangaspero, F.7
Giannini, C.8
Mokhtari, K.9
Mork, S.J.10
Paetau, A.11
Reifenberger, G.12
Van Den Bent, M.J.13
-
22
-
-
79951611375
-
Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis
-
Laffaire J, Everhard S, Idbaih A, Criniere E, Marie Y, de Reynies A, Schiappa R, Mokhtari K, Hoang-Xuan K, Sanson M, Delattre JY, Thillet J, Ducray F. 2010. Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis. Neuro Oncol 13:84-98.
-
(2010)
Neuro Oncol
, vol.13
, pp. 84-98
-
-
Laffaire, J.1
Everhard, S.2
Idbaih, A.3
Criniere, E.4
Marie, Y.5
de Reynies, A.6
Schiappa, R.7
Mokhtari, K.8
Hoang-Xuan, K.9
Sanson, M.10
Delattre, J.Y.11
Thillet, J.12
Ducray, F.13
-
23
-
-
62449321780
-
Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes
-
Li A, Walling J, Ahn S, Kotliarov Y, Su Q, Quezado M, Oberholtzer JC, Park J, Zenklusen JC, Fine HA. 2009. Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes. Cancer Res 69:2091-2099.
-
(2009)
Cancer Res
, vol.69
, pp. 2091-2099
-
-
Li, A.1
Walling, J.2
Ahn, S.3
Kotliarov, Y.4
Su, Q.5
Quezado, M.6
Oberholtzer, J.C.7
Park, J.8
Zenklusen, J.C.9
Fine, H.A.10
-
24
-
-
69949087520
-
A microarray-based DNA methylation study of glioblastoma multiforme
-
Martinez R, Martin-Subero JI, Rohde V, Kirsch M, Alaminos M, Fernandez AF, Ropero S, Schackert G, Esteller M. 2009. A microarray-based DNA methylation study of glioblastoma multiforme. Epigenetics 4:255-264.
-
(2009)
Epigenetics
, vol.4
, pp. 255-264
-
-
Martinez, R.1
Martin-Subero, J.I.2
Rohde, V.3
Kirsch, M.4
Alaminos, M.5
Fernandez, A.F.6
Ropero, S.7
Schackert, G.8
Esteller, M.9
-
25
-
-
0036815848
-
Neuropathological diagnostic accuracy
-
Murphy M, Loosemore A, Ferrer I, Wesseling P, Wilkins PR, Bell BA. 2002. Neuropathological diagnostic accuracy. Br J Neurosurg 16:461-464.
-
(2002)
Br J Neurosurg
, vol.16
, pp. 461-464
-
-
Murphy, M.1
Loosemore, A.2
Ferrer, I.3
Wesseling, P.4
Wilkins, P.R.5
Bell, B.A.6
-
26
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, Ding L, Wilson RK, Van Den Berg D, Shen H, Bengtsson H, Neuvial P, Cope LM, Buckley J, Herman JG, Baylin SB, Laird PW, Aldape K. 2010. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17:510-522.
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
Pan, F.7
Pelloski, C.E.8
Sulman, E.P.9
Bhat, K.P.10
Verhaak, R.G.11
Hoadley, K.A.12
Hayes, D.N.13
Perou, C.M.14
Schmidt, H.K.15
Ding, L.16
Wilson, R.K.17
Van Den Berg, D.18
Shen, H.19
Bengtsson, H.20
Neuvial, P.21
Cope, L.M.22
Buckley, J.23
Herman, J.G.24
Baylin, S.B.25
Laird, P.W.26
Aldape, K.27
more..
-
27
-
-
82255183048
-
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
-
Pansuriya TC, van Eijk R, d'Adamo P, van Ruler MA, Kuijjer ML, Oosting J, Cleton-Jansen AM, van Oosterwijk JG, Verbeke SL, Meijer D, van Wezel T, Nord KH, Sangiorgi L, Toker B, Liegl-Atzwanger B, San-Julian M, Sciot R, Limaye N, Kindblom LG, Daugaard S, Godfraind C, Boon LM, Vikkula M, Kurek KC, Szuhai K, French PJ, Bovee JV. 2011. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat Genet 43:1256-1261.
-
(2011)
Nat Genet
, vol.43
, pp. 1256-1261
-
-
Pansuriya, T.C.1
van Eijk, R.2
d'Adamo, P.3
van Ruler, M.A.4
Kuijjer, M.L.5
Oosting, J.6
Cleton-Jansen, A.M.7
van Oosterwijk, J.G.8
Verbeke, S.L.9
Meijer, D.10
van Wezel, T.11
Nord, K.H.12
Sangiorgi, L.13
Toker, B.14
Liegl-Atzwanger, B.15
San-Julian, M.16
Sciot, R.17
Limaye, N.18
Kindblom, L.G.19
Daugaard, S.20
Godfraind, C.21
Boon, L.M.22
Vikkula, M.23
Kurek, K.C.24
Szuhai, K.25
French, P.J.26
Bovee, J.V.27
more..
-
28
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K. 2006. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157-173.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
Misra, A.7
Nigro, J.M.8
Colman, H.9
Soroceanu, L.10
Williams, P.M.11
Modrusan, Z.12
Feuerstein, B.G.13
Aldape, K.14
-
29
-
-
0029042988
-
Central pathology review in clinical trials for patients with malignant glioma. A report of radiation therapy oncology group 83-02
-
Scott CB, Nelson JS, Farnan NC, Curran WJ, Jr., Murray KJ, Fischbach AJ, Gaspar LE, Nelson DF. 1995. Central pathology review in clinical trials for patients with malignant glioma. A report of radiation therapy oncology group 83-02. Cancer 76:307-313.
-
(1995)
Cancer
, vol.76
, pp. 307-313
-
-
Scott, C.B.1
Nelson, J.S.2
Farnan, N.C.3
Curran Jr, W.J.4
Murray, K.J.5
Fischbach, A.J.6
Gaspar, L.E.7
Nelson, D.F.8
-
31
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP. 1999. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 96:8681-8686.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
32
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA. 2012. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483:479-478.
-
(2012)
Nature
, vol.483
, pp. 479-478
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
Walsh, L.A.4
Fang, F.5
Yilmaz, E.6
Campos, C.7
Fabius, A.W.8
Lu, C.9
Ward, P.S.10
Thompson, C.B.11
Kaufman, A.12
Guryanova, O.13
Levine, R.14
Heguy, A.15
Viale, A.16
Morris, L.G.17
Huse, J.T.18
Mellinghoff, I.K.19
Chan, T.A.20
more..
-
33
-
-
73349121355
-
MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: A report from EORTC Brain Tumor Group Study 26951
-
van den Bent MJ, Dubbink HJ, Sanson M, van der Lee-Haarloo CR, Hegi M, Jeuken JW, Ibdaih A, Brandes AA, Taphoorn MJ, Frenay M, Lacombe D, Gorlia T, Dinjens WN, Kros JM. 2009. MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: A report from EORTC Brain Tumor Group Study 26951. J Clin Oncol 27:5881-5886.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5881-5886
-
-
Van Den Bent, M.J.1
Dubbink, H.J.2
Sanson, M.3
Van Der Lee-Haarloo, C.R.4
Hegi, M.5
Jeuken, J.W.6
Ibdaih, A.7
Brandes, A.A.8
Taphoorn, M.J.9
Frenay, M.10
Lacombe, D.11
Gorlia, T.12
Dinjens, W.N.13
Kros, J.M.14
-
34
-
-
81255128997
-
A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951
-
van den Bent MJ, Gravendeel LA, Gorlia T, Kros JM, Lapre L, Wesseling P, Teepen JL, Idbaih A, Sanson M, Smitt PA, French PJ. 2011. A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951. Clin Cancer Res 17:7148-7155.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7148-7155
-
-
Van Den Bent, M.J.1
Gravendeel, L.A.2
Gorlia, T.3
Kros, J.M.4
Lapre, L.5
Wesseling, P.6
Teepen, J.L.7
Idbaih, A.8
Sanson, M.9
Smitt, P.A.10
French, P.J.11
-
35
-
-
0042384763
-
A new algorithm for hybrid hierarchical clustering with visualization and the bootstrap
-
Van der Laan MJ, Pollard KS. 2003. A new algorithm for hybrid hierarchical clustering with visualization and the bootstrap. J Stat Plan Inference 117:275-303.
-
(2003)
J Stat Plan Inference
, vol.117
, pp. 275-303
-
-
Van der Laan, M.J.1
Pollard, K.S.2
-
36
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN. 2010. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
Alexe, G.11
Lawrence, M.12
O'Kelly, M.13
Tamayo, P.14
Weir, B.A.15
Gabriel, S.16
Winckler, W.17
Gupta, S.18
Jakkula, L.19
Feiler, H.S.20
Hodgson, J.G.21
James, C.D.22
Sarkaria, J.N.23
Brennan, C.24
Kahn, A.25
Spellman, P.T.26
Wilson, R.K.27
Speed, T.P.28
Gray, J.W.29
Meyerson, M.30
Getz, G.31
Perou, C.M.32
Hayes, D.N.33
more..
-
37
-
-
84861407516
-
Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production
-
Ward PS, Cross JR, Lu C, Weigert O, Abel-Wahab O, Levine RL, Weinstock DM, Sharp KA, Thompson CB. 2012. Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. Oncogene 31:2491-2498.
-
(2012)
Oncogene
, vol.31
, pp. 2491-2498
-
-
Ward, P.S.1
Cross, J.R.2
Lu, C.3
Weigert, O.4
Abel-Wahab, O.5
Levine, R.L.6
Weinstock, D.M.7
Sharp, K.A.8
Thompson, C.B.9
-
38
-
-
77950813610
-
CpG island hypermethylation in human astrocytomas
-
Wu X, Rauch TA, Zhong X, Bennett WP, Latif F, Krex D, Pfeifer GP. 2010. CpG island hypermethylation in human astrocytomas. Cancer Res 70:2718-2727.
-
(2010)
Cancer Res
, vol.70
, pp. 2718-2727
-
-
Wu, X.1
Rauch, T.A.2
Zhong, X.3
Bennett, W.P.4
Latif, F.5
Krex, D.6
Pfeifer, G.P.7
-
39
-
-
78651463452
-
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. 2011. Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19:17-30.
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.H.6
Ito, S.7
Yang, C.8
Wang, P.9
Xiao, M.T.10
Liu, L.X.11
Jiang, W.Q.12
Liu, J.13
Zhang, J.Y.14
Wang, B.15
Frye, S.16
Zhang, Y.17
Xu, Y.H.18
Lei, Q.Y.19
Guan, K.L.20
Zhao, S.M.21
Xiong, Y.22
more..
|