ML264, A novel small-molecule compound that potently inhibits growth of colorectal cancer

Molecular Cancer Therapeutics

Volumn 15, Issue 1, 2016, Pages 72-83

  De Sabando, Ainara Ruiz ^a   Wang, Chao ^b   He, Yuanjun ^b   García Barros, Mónica ^c   Kim, Julie ^a   Shroyer, Kenneth R ^a   Bannister, Thomas D ^b   Yang, Vincent W ^a   Bialkowska, Agnieszka B ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Stony Brook School of Dental Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; CYCLIN A2; CYCLIN B; CYCLIN B1; CYCLIN D1; CYCLIN E; EARLY GROWTH RESPONSE FACTOR 1; GLYCOGEN SYNTHASE KINASE 3BETA; KRUPPEL LIKE FACTOR 5; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; ML 264; PI3K PROTEIN; PROTEIN; RAS PROTEIN; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE 1; UNCLASSIFIED DRUG; VIMENTIN; WNT PROTEIN; ACRYLAMIDE DERIVATIVE; BIOLOGICAL MARKER; CYCLINE; ML264 COMPOUND; PHOSPHATIDYLINOSITOL 3 KINASE; SULFOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL COUNT; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOSIS; MOUSE; MTS ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; S PHASE CELL CYCLE CHECKPOINT; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANIMAL; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG SCREENING; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACRYLAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOMARKERS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIC S-OXIDES; CYCLINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; RAS PROTEINS; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84958158725     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-15-0600     Document Type: Article

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