Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon

Developmental Biology

Volumn 387, Issue 2, 2014, Pages 191-202

  Nandan, Mandayam O ^a   Ghaleb, Amr M ^a   Liu, Yang ^a   Bialkowska, Agnieszka B ^a   McConnell, Beth B ^b   Shroyer, Kenneth R ^a   Robine, Sylvie ^c   Yang, Vincent W ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUT CURIE   (France)

Author keywords

Colon; Cre recombinase; Differentiation; Epithelium; Inducible deletion; Intestine; KLF5; Proliferation; Reg1A; Regeneration; Sox9

Indexed keywords

KRUPPEL LIKE FACTOR 5; TAMOXIFEN; TRANSCRIPTION FACTOR SOX9; CYCLIN B2; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; KI 67 ANTIGEN;

ADULT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COLON MUCOSA; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GOBLET CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MICROARRAY ANALYSIS; MORPHOLOGY; MOUSE; NONHUMAN; PANETH CELL; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REG1A GENE; REG3B GENE; REG3G GENE; TISSUE REGENERATION; TUMOR VOLUME; ANIMAL CELL; CDC2 GENE; COLON REGENERATION; CRYPT CELL; CYCLIN B GENE; CYCLIN D1 GENE; GENE EXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; KI 67 GENE; KLF5 GENE; LETHALITY; REGENERATIVE ABILITY; SOX9 GENE; WEIGHT REDUCTION;

MUS;

COLON; CRE RECOMBINASE; DIFFERENTIATION; EPITHELIUM; INDUCIBLE DELETION; INTESTINE; KLF5; PROLIFERATION; REG1A; REGENERATION; SOX9;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL PROLIFERATION; COLON; COLORECTAL NEOPLASMS; CYCLIN B; CYCLIN D1; DOWN-REGULATION; GOBLET CELLS; HCT116 CELLS; HEK293 CELLS; HUMANS; KI-67 ANTIGEN; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LITHOSTATHINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PANETH CELLS; PROMOTER REGIONS, GENETIC; PROTEINS; REGENERATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE DELETION; SIGNAL TRANSDUCTION; SOX9 TRANSCRIPTION FACTOR; TAMOXIFEN; UP-REGULATION;

EID: 84894630587     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.01.002     Document Type: Article

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