Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats

Archives of Pharmacal Research

Volumn 39, Issue 2, 2016, Pages 221-230

  Gao, Dawei ^a   Zhao, Min ^b   Qi, Ximing ^b   Liu, Yanping ^a   Li, Nan ^a   Liu, Zhiwei ^a   Bian, Yanhong ^a  

^a YANSHAN UNIVERSITY   (China)

^b The No1 Hospital of Qinhuangdao   (China)

Author keywords

Gynostemma pentaphyllum saponins; Hypoglycemia; Insulin; Nuclear factor erythroid 2 related factor 2 (Nrf2); Reactive oxygen species

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; GLUCOSE; GLUTATHIONE; INSULIN; MALONALDEHYDE; SAPONIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GLUTATHIONE PEROXIDASE; LIPID; NFE2L2 PROTEIN, RAT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CLEARANCE; CONTROLLED STUDY; DIABETES MELLITUS; DYSLIPIDEMIA; GLUCOSE BLOOD LEVEL; GYNOSTEMMA PENTAPHYLLUM; INSULIN BLOOD LEVEL; KIDNEY; LIVER; MALE; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PANCREAS; RAT; SIGNAL TRANSDUCTION; SPLEEN; THYMUS; ANIMAL; BLOOD; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GYNOSTEMMA; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; PHYTOTHERAPY; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BIOMARKERS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; GLUTATHIONE PEROXIDASE; GYNOSTEMMA; HYPOGLYCEMIC AGENTS; INSULIN; KIDNEY; LIPIDS; LIVER; MALE; MALONDIALDEHYDE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS, WISTAR; SAPONINS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 84958125701     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-014-0441-2     Document Type: Article

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