Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Science Translational Medicine

Volumn 8, Issue 324, 2016, Pages

  Yang, Guangrui ^a   Chen, Lihong ^a   Grant, Gregory R ^a,b   Paschos, Georgios ^a   Song, Wen Liang ^a   Musiek, Erik S ^c   Lee, Vivian ^d   McLoughlin, Sarah C ^a   Grosser, Tilo ^a   Cotsarelis, George ^a   Fitzgerald, Garret A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; TRANSCRIPTION FACTOR ARNTL; ARNTL PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; TRANSCRIPTOME;

ADULT; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHROPATHY; ARTICLE; ASTROCYTOSIS; BLOOD PRESSURE; BMAL1 GENE; BODY WEIGHT; CIRCADIAN RHYTHM; CONTROLLED STUDY; EYE DISEASE; FERTILITY; GENE EXPRESSION; GENE FUNCTION; GLUCOSE BLOOD LEVEL; HAIR GROWTH; HEART RATE; LIFESPAN; MALE; MOLECULAR CLOCK; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; WILD TYPE; ANIMAL; ATHEROSCLEROSIS; DEFICIENCY; EYE MALFORMATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GLIOSIS; GROWTH, DEVELOPMENT AND AGING; HAIR; KNOCKOUT MOUSE; LIPID DIET; LONGEVITY; METABOLISM; PATHOLOGY; PHENOTYPE; SURVIVAL ANALYSIS; TIME FACTOR;

AGING; ANIMALS; ARNTL TRANSCRIPTION FACTORS; ATHEROSCLEROSIS; BLOOD GLUCOSE; CIRCADIAN CLOCKS; CIRCADIAN RHYTHM; DIET, HIGH-FAT; EYE ABNORMALITIES; FERTILITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLIOSIS; HAIR; LONGEVITY; MICE, KNOCKOUT; PHENOTYPE; SURVIVAL ANALYSIS; TIME FACTORS; TRANSCRIPTOME;

EID: 84958092932     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aad3305     Document Type: Article

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