HIV-1 vpr protein induces proteasomal degradation of chromatin-associated class I HDACs to overcome latent infection of macrophages

Journal of Biological Chemistry

Volumn 291, Issue 6, 2016, Pages 2696-2711

  Romani, Bizhan ^a,b   Baygloo, Nima Shaykh ^a   Hamidi Fard, Mojtaba ^c   Aghasadeghi, Mohammad Reza ^c   Allahbakhshi, Elham ^b  

^a UNIVERSITY OF ISFAHAN   (Iran)

^b AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; MACROPHAGES; PROTEINS; VIRUSES;

CLASS I; HYPERACETYLATION; PROMOTOR; PROTEASOMAL DEGRADATION;

DISEASES;

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 8; VPR PROTEIN; CHROMATIN; HISTONE; HISTONE DEACETYLASE; PROTEASOME; VPR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ADULT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ACETYLATION; CHROMATIN; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERMINAL REPEAT; METABOLISM; PATHOLOGY; PHYSIOLOGY; VIROLOGY; VIRUS LATENCY;

ACETYLATION; CHROMATIN; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HELA CELLS; HISTONE DEACETYLASES; HISTONES; HIV INFECTIONS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; MACROPHAGES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; VIRUS LATENCY; VPR GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84957998801     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.689018     Document Type: Article

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