In vitro and in vivo evaluation of novel implantation technology in hydrogel contact lenses for controlled drug delivery

Journal of Controlled Release

Volumn 226, Issue , 2016, Pages 47-56

  Maulvi, Furqan A ^a   Lakdawala, Dhara H ^a   Shaikh, Anjum A ^a   Desai, Ankita R ^a   Choksi, Harsh H ^a   Vaidya, Rutvi J ^a   Ranch, Ketan M ^a   Koli, Akshay R ^a   Vyas, Bhavin A ^a   Shah, Dinesh O ^b,c,d,e  

^a UKA TARSADIA UNIVERSITY   (India)

^b DHARMSINH DESAI UNIVERSITY   (India)

^c J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^d Columbia University ^*  (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Controlled drug delivery; Hydrogel contact lenses; Pharmacodynamic study; Pharmacokinetic study; Ring implantation; Timolol maleate

Indexed keywords

CELLULOSE; CONTACT LENSES; DROPS; DRUG PRODUCTS; EMULSIFICATION; HYDROGELS; INTRAOCULAR LENSES; LENSES; NANOPARTICLES; OPHTHALMOLOGY; PHARMACODYNAMICS; PHARMACOKINETICS; X RAY DIFFRACTION;

HYDROGEL CONTACT LENS; IMPLANTATION TECHNOLOGY; INTRA OCULAR PRESSURE; PHARMACODYNAMIC DATA; PHARMACOKINETIC STUDIES; SUSTAINED DRUG RELEASE; TIMOLOL MALEATE; X-RAY DIFFRACTION STUDIES;

CONTROLLED DRUG DELIVERY;

2 HYDROXYETHYL METHACRYLATE; ACRYLIC ACID; ETHYL CELLULOSE; ETHYLENE GLYCOL DIMETHACRYLATE; EYE DROPS; NANOPARTICLE; TIMOLOL MALEATE; ANTIHYPERTENSIVE AGENT; DELAYED RELEASE FORMULATION; HYDROGEL; TIMOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTACT LENS; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DEVICE SAFETY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; EYE IRRITATION; GLAUCOMA; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR PRESSURE; LACRIMAL FLUID; LENS IMPLANT; LENS IMPLANTATION; MEAN RESIDENCE TIME; NANOEMULSION; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SUSTAINED DRUG RELEASE; THERAPEUTIC INDEX; X RAY DIFFRACTION; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DEVICES; DRUG EFFECTS; EQUIPMENT DESIGN; FEMALE; MALE; PATHOPHYSIOLOGY; RABBITS AND HARES;

COATINGS; DRUGS; EMULSIONS; ETHYL CELLULOSE; X RAY DIFFRACTION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CONTACT LENSES; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; FEMALE; GLAUCOMA; HYDROGEL; INTRAOCULAR PRESSURE; MALE; OPHTHALMIC SOLUTIONS; RABBITS; TIMOLOL;

EID: 84957928326     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.02.012     Document Type: Article

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