Liposome incorporated ion sensitive in situ gels for opthalmic delivery of timolol maleate

International Journal of Pharmaceutics

Volumn 480, Issue 1-2, 2015, Pages 128-136

  Yu, Shihui ^a   Wang, Qi Ming ^b   Wang, Xin ^a   Liu, Dandan ^c   Zhang, Wenji ^a   Ye, Tiantian ^a   Yang, Xinggang ^a   Pan, Weisan ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c LIAONING INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Deacetylated gellan gum; Liposomal ion sensitivity in situ gel; Ocular drug delivery system; Pharmacodynamics; Timolol maleate

Indexed keywords

EYE DROPS; GELLAN; LIPOSOME; RHODAMINE B; TIMOLOL MALEATE; WATER; ANTIHYPERTENSIVE AGENT; BACTERIAL POLYSACCHARIDE; GEL; TIMOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG INSTILLATION; DRUG PENETRATION; ENCAPSULATION; FEMALE; GAMMA SCINTIGRAPHY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HYDROGEL; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; LIPID VESICLE; LIPOSOMAL DELIVERY; MALE; NEW ZEALAND RABBIT; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; ROOM TEMPERATURE; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; WATER LOADING; ZETA POTENTIAL; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; GEL; INTRAOCULAR DRUG ADMINISTRATION; METABOLISM; PERMEABILITY; RABBIT; TIME FACTOR;

ADMINISTRATION, OPHTHALMIC; ANIMALS; ANTIHYPERTENSIVE AGENTS; CORNEA; DRUG DELIVERY SYSTEMS; FEMALE; GELS; HYDROGEN-ION CONCENTRATION; INTRAOCULAR PRESSURE; LIPOSOMES; MALE; OPHTHALMIC SOLUTIONS; PERMEABILITY; POLYSACCHARIDES, BACTERIAL; RABBITS; TIME FACTORS; TIMOLOL;

EID: 84921762501     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.01.032     Document Type: Article

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