Effects of L. paracasei subp. paracasei X12 on cell cycle of colon cancer HT-29 cells and regulation of mTOR signalling pathway

Journal of Functional Foods

Volumn 21, Issue , 2016, Pages 431-439

  Huang, Lei ^a   Shan, Yu Juan ^a   He, Can Xia ^a   Ren, Ming Hua ^b   Tian, Pei Jun ^a   Song, Wei ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Cell cycle; Colon cancer; MTOR signalling pathway; Probiotics

Indexed keywords

EID: 84957893443     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2015.12.024     Document Type: Article

References (40)

1. Bruce W.R., Wolever T.M., Giacca A. Mechanisms linking diet and colorectal cancer: The possible role of insulin resistance. Nutrition and Cancer 2000, 37(1):19-26.
2. Burn J., Gerdes A.M., Macrae F., Mecklin J.P., Moeslein G., Olschwang S., Eccles D., Evans D.G., Maher E.R., Bertario L., Bisgaard M.L., Dunlop M.G., Ho J.W., Hodgson S.V., Lindblom A., Lubinski J., Morrison P.J., Murday V., Ramesar R., Side L., Scott R.J., Thomas H.J., Vasen H.F., Barker G., Crawford G., Elliott F., Movahedi M., Pylvanainen K., Wijnen J.T., Fodde R., Lynch H.T., Mathers J.C., Bishop D.T. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: An analysis from the CAPP2 randomised controlled trial. The Lancet 2012, 378(9809):2081-2087.
3. Chen Z.F., Ai L.Y., Wang J.L., Ren L.L., Yu Y.N., Xu J., Chen H.Y., Yu J., Li M., Qin W.X., Ma X., Shen N., Chen Y.X., Hong J., Fang J.Y. Probiotics Clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis. Future Microbiology 2015, 10(9):1433-1445.
4. Chien W., Lee D.H., Zheng Y., Wuensche P., Alvarez R., Wen D.L., Aribi A.M., Thean S.M., Doan N.B., Said J.W., Koeffler H.P. Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo. Molecular Carcinogenesis 2014, 53(9):722-735.
5. David L.A., Maurice C.F., Carmody R.N., Gootenberg D.B., Button J.E., Wolfe B.E., Ling A.V., Devlin A.S., Varma Y., Fischbach M.A., Biddinger S.B., Dutton R.J., Turnbaugh P.J. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014, 505(7484):559-563.
6. Davis C.D., Milner J.A. Gastrointestinal microflora, food components and colon cancer prevention. The Journal of Nutritional Biochemistry 2009, 20(10):743-752.
7. De Filippo C., Cavalieri D., Di Paola M., Ramazzotti M., Poullet J.B., Massart S., Collini S., Pieraccini G., Lionetti P. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences of the United States of America 2010, 107(33):14691-14696.
8. Duncan S.H., Belenguer A., Holtrop G., Johnstone A.M., Flint H.J., Lobley G.E. Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Applied and Environmental Microbiology 2007, 73(4):1073-1078.
9. Elmore S. Apoptosis: A review of programmed cell death. Toxicologic Pathology 2007, 35(4):495-516.
10. Femia A.P., Luceri C., Dolara P., Giannini A., Biggeri A., Salvadori M., Clune Y., Collins K.J., Paglierani M., Caderni G. Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats. Carcinogenesis 2002, 23(11):1953-1960.
11. Gulhati P., Bowen K.A., Liu J., Stevens P.D., Rychahou P.G., Chen M., Lee E.Y., Weiss H.L., O'Connor K.L., Gao T., Evers B.M. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways. Cancer Research 2011, 71(9):3246-3256.
12. Hartwell L.H., Kastan M.B. Cell cycle control and cancer. Science 1994, 266(5192):1821-1828.
13. Hu P., Song W., Shan Y., Du M., Huang M., Song C., Zhang L. Lactobacillus paracasei supsp. paracasei M5L induces cell cycle arrest and calreticulin translocation via the generation of reactive oxygen species in HT-29 cell apoptosis. Food & Function 2015, 6(7):2257-2265.
14. Huang S., Houghton P.J. Targeting mTOR signaling for cancer therapy. Current Opinion in Pharmacology 2003, 3(4):371-377.
15. Iyer C., Kosters A., Sethi G., Kunnumakkara A.B., Aggarwal B.B., Versalovic J. Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-κB and MAPK signalling. Cellular Microbiology 2008, 10(7):1442-1452.
16. Jemal A., Center M.M., DeSantis C., Ward E.M. Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiology Biomarkers & Prevention 2010, 19(8):1893-1907.
17. Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D. Global cancer statistics. CA: A Cancer Journal for Clinicians 2011, 61(2):69-90.
18. Kim N., Kim J.E., Choung H.K., Lee M.J., Khwarg S.I. Expression of cell cycle regulatory proteins in eyelid sebaceous gland carcinoma: Low p27 expression predicts poor prognosis. Experimental Eye Research 2014, 118:46-52.
19. Laplante M., Sabatini D.M. mTOR signaling in growth control and disease. Cell 2012, 149(2):274-293.
20. Lee M., Theodoropoulou M., Graw J., Roncaroli F., Zatelli M.C., Pellegata N.S. Levels of p27 sensitize to dual PI3K/mTOR inhibition. Molecular Cancer Therapeutics 2011, 10(8):1450-1459.
21. Lim M., Hussain Z., Howe A., Storey R., Petty D., Haselden J., Sebag-Montefiore D., Alexander D. The oncological outcome after right hemicolectomy and accuracy of CT scan as a preoperative tool for staging in right sided colonic cancers. Colorectal Disease 2013, 15(5):536-543.
22. Massagué J. G1 cell-cycle control and cancer. Nature 2004, 432(7015):298-306.
23. Meeker S., Seamons A., Paik J., Treuting P.M., Brabb T., Grady W.M., Maggio-Price L. Increased dietary vitamin D suppresses MAPK signaling, colitis, and colon cancer. Cancer Research 2014, 74(16):4398-4408.
24. Moorehead R., Hoper M., McKelvey S. Assessment of ornithine decarboxylase activity in rectal mucosa as a marker for colorectal adenomas and carcinomas. British Journal of Surgery 1987, 74(5):364-365.
25. Moschetta M., Reale A., Marasco C., Vacca A., Carratù M. Therapeutic targeting of the mTOR-signalling pathway in cancer: Benefits and limitations. British Journal of Pharmacology 2014, 171(16):3801-3813.
26. Nagao T., Kurosu T., Umezawa Y., Nogami A., Oshikawa G., Tohda S., Yamamoto M., Miura O. Proliferation and survival signaling from both Jak2-V617F and lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-cell line newly established from acute myeloid leukemia transformed from polycythemia vera. PLoS ONE 2014, 9(1):e84746.
27. Roulin D., Cerantola Y., Dormond-Meuwly A., Demartines N., Dormond O. Short communication: Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo 2010.
28. Salonen A., Lahti L., Salojärvi J., Holtrop G., Korpela K., Duncan S.H., Date P., Farquharson F., Johnstone A.M., Lobley G.E., Louis P., Flint H.J., de Vos W.M. Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men. The ISME Journal 2014, 8:2218-2230.
29. Shan Y., Zhang L., Bao Y., Li B., He C., Gao M., Feng X., Xu W., Zhang X., Wang S. Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells. The Journal of Nutritional Biochemistry 2013, 24(6):1062-1069.
30. Sikalidis A.K., Fitch M.D., Fleming S.E. Diet induced obesity increases the risk of colonic tumorigenesis in mice. Pathology Oncology Research 2013, 19(4):657-666.
31. Tian P.J., Li B.L., Shan Y.J., Zhang J.N., Chen J.Y., Yu M., Zhang L.W. Extraction of peptidoglycan from L. paracasei subp. paracasei X12 and its preliminary mechanisms of inducing immunogenic cell death in HT-29 cells. International Journal of Molecular Sciences 2015, 16(8):20033-20049.
32. Uccello M., Malaguarnera G., Basile F., D'agata V., Malaguarnera M., Bertino G., Vacante M., Drago F., Biondi A. Potential role of probiotics on colorectal cancer prevention. BMC Surgery 2012, 12(Suppl. 1):S35.
33. Walker A.W., Ince J., Duncan S.H., Webster L.M., Holtrop G., Ze X., Brown D., Stares M.D., Scott P., Bergerat A., Louis P., McIntosh F., Johnstone A.M., Lobley G.E., Parkhill J., Flint H.J. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. The ISME Journal 2011, 5(2):220-230.
34. Wang S.M., Zhang L.W., Fan R.B., Han X., Yi H.X., Zhang L.L., Xue C.H., Li H.B., Zhang Y.H., Shigwedha N. Induction of HT-29 cells apoptosis by lactobacilli isolated from fermented products. Research in Microbiology 2014, 165(3):202-214.
35. Weijenberg M.P., Mullie P.F., Brants H.A., Heinen M.M., Goldbohm R.A., van den Brandt P.A. Dietary glycemic load, glycemic index and colorectal cancer risk: Results from the Netherlands Cohort Study. International Journal of Cancer 2008, 122(3):620-629.
36. Wiseman M. The second World Cancer Research Fund/American Institute for Cancer Research expert report. Food, nutrition, physical activity, and the prevention of cancer: A global perspective. Proceedings of the Nutrition Society 2008, 67(03):253-256.
37. Wu G.D., Chen J., Hoffmann C., Bittinger K., Chen Y.Y., Keilbaugh S.A., Bewtra M., Knights D., Walters W.A., Knight R., Sinha R., Gilroy E., Gupta K., Baldassano R., Nessel L., Li H., Bushman F.D., Lewis J.D. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011, 334(6052):105-108.
38. Yoshimoto S., Loo T.M., Atarashi K., Kanda H., Sato S., Oyadomari S., Iwakura Y., Oshima K., Morita H., Hattori M., Honda K., Ishikawa Y., Hara E., Ohtani N. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 2013, 499(7456):97-101.
39. Zackular J.P., Baxter N.T., Iverson K.D., Sadler W.D., Petrosino J.F., Chen G.Y., Schloss P.D. The gut microbiome modulates colon tumorigenesis. MBio 2013, 4(6). e00692-13.
40. Zhu Q.C., Gao R.Y., Wu W., Guo B.M., Peng J.Y., Qin H.L. Effect of a high-fat diet in development of colonic adenoma in an animal model. World Journal of Gastroenterology: WJG 2014, 20(25):8119.