Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells

Journal of Nutritional Biochemistry

Volumn 24, Issue 6, 2013, Pages 1062-1069

  Shan, Yujuan ^a,b   Zhang, Lanwei ^a   Bao, Yongping ^c   Li, Baolong ^d   He, Canxia ^b   Gao, Mingming ^b   Feng, Xue ^b   Xu, Weili ^a   Zhang, Xiaohong ^e   Wang, Shuran ^b  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^e NINGBO UNIVERSITY   (China)

Author keywords

Bladder cancer; E cadherin; Epithelial mesenchymal transition; Metastasis; Sulforaphane

Indexed keywords

CYCLOOXYGENASE 2; GELATINASE A; GELATINASE B; MICRORNA 200C; SULFORAPHANE; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN;

ARTICLE; BLADDER CANCER; CANCER CELL; CELL ADHESION; CELL INVASION; CELL MIGRATION; CHEMOTAXIS; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; PROTEIN EXPRESSION; TUMOR INVASION;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CYCLOOXYGENASE 2; EPITHELIAL-MESENCHYMAL TRANSITION; HOMEODOMAIN PROTEINS; HUMANS; ISOTHIOCYANATES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICRORNAS; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; URINARY BLADDER NEOPLASMS;

GASTROPODA;

EID: 84878011356     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.08.004     Document Type: Article

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