Modification of the host cell lipid metabolism induced by hypolipidemic drugs targeting the acetyl coenzyme A carboxylase impairs West Nile virus replication

Antimicrobial Agents and Chemotherapy

Volumn 60, Issue 1, 2016, Pages 307-315

  Merino Ramos, Teresa ^a   Vázquez Calvo, Ángela ^a   Casas, Josefina ^b   Sobrino, Francisco ^c   Saiz, Juan Carlos ^a   Martín Acebes, Miguel A ^a,c  

^a INIA   (Spain)

^b INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3,3,14,14 TETRAMETHYLHEXADECANEDIOIC ACID; 5 (TETRADECYLOXY) 2 FUROIC ACID; ACETYL COENZYME A CARBOXYLASE; ANTILIPEMIC AGENT; CERAMIDE; CHOLESTEROL; CHOLESTEROL ESTER; DIACYLGLYCEROL; ENZYME INHIBITOR; GLYCEROPHOSPHOLIPID; LACTOSYLCERAMIDE; MONOHEXOSYLCERAMIDE; SPHINGOLIPID; SPHINGOMYELIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 5-(TETRADECYLOXY)-2-FURANCARBOXYLIC ACID; ANTIVIRUS AGENT; FURAN DERIVATIVE; PALMITIC ACID DERIVATIVE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; FLAVIVIRUS; HOST CELL; LIPID BLOOD LEVEL; LIPID COMPOSITION; LIPID METABOLISM; LIPIDOMICS; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; USUTU VIRUS; VIRUS REPLICATION; WEST NILE VIRUS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HELA CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; MOUSE; NERVE CELL; VERO CELL LINE; VIROLOGY;

ACETYL-COA CARBOXYLASE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CERCOPITHECUS AETHIOPS; CHOLESTEROL; ENZYME INHIBITORS; FURANS; GENE EXPRESSION; GLYCEROPHOSPHOLIPIDS; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; MICE; NEURONS; PALMITIC ACIDS; SPHINGOLIPIDS; VERO CELLS; VIRUS REPLICATION; WEST NILE VIRUS;

EID: 84957889595     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01578-15     Document Type: Article

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