-
2
-
-
62149144052
-
Allergic bronchopulmonary aspergillosis
-
Agarwal R. Allergic bronchopulmonary aspergillosis. Chest 2009;135:805-26.
-
(2009)
Chest
, vol.135
, pp. 805-826
-
-
Agarwal, R.1
-
3
-
-
0034854083
-
Diagnosis and treatment of allergic bronchopulmonary aspergillosis
-
Vlahakis NE, Aksamit TR. Diagnosis and treatment of allergic bronchopulmonary aspergillosis. Mayo Clin Proc 2001;76:930-8.
-
(2001)
Mayo Clin Proc
, vol.76
, pp. 930-938
-
-
Vlahakis, N.E.1
Aksamit, T.R.2
-
4
-
-
32644447957
-
The link between fungi and severe asthma: A summary of the evidence
-
Denning DW, O'Driscoll BR, Hogaboam CM, et al. The link between fungi and severe asthma: a summary of the evidence. Eur Respir J 2006;27:615-26.
-
(2006)
Eur Respir J
, vol.27
, pp. 615-626
-
-
Denning, D.W.1
O'Driscoll, B.R.2
Hogaboam, C.M.3
-
5
-
-
79953754855
-
Aspergillus sensitization is associated with airflow limitation and bronchiectasis in severe asthma
-
Menzies D, Holmes L, McCumesky G, et al. Aspergillus sensitization is associated with airflow limitation and bronchiectasis in severe asthma. Allergy 2011;66:679-85.
-
(2011)
Allergy
, vol.66
, pp. 679-685
-
-
Menzies, D.1
Holmes, L.2
McCumesky, G.3
-
6
-
-
0037382808
-
Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
-
Kwak YG, Song CH, Yi HK, et al. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J Clin Invest 2003;111:1083-92.
-
(2003)
J Clin Invest
, vol.111
, pp. 1083-1092
-
-
Kwak, Y.G.1
Song, C.H.2
Yi, H.K.3
-
7
-
-
0032497832
-
Structure and function of phosphoinositide 3-kinases
-
Wymann MP, Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim Biophys Acta 1998;1436:127-50.
-
(1998)
Biochim Biophys Acta
, vol.1436
, pp. 127-150
-
-
Wymann, M.P.1
Pirola, L.2
-
8
-
-
16244393685
-
Signalling by PI3K isoforms: Insights from gene-targeted mice
-
Vanhaesebroeck B, Ali K, Bilancio A, et al. Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem Sci 2005;30:194-204.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 194-204
-
-
Vanhaesebroeck, B.1
Ali, K.2
Bilancio, A.3
-
9
-
-
0037047590
-
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice
-
Okkenhaug K, Bilancio A, Farjot G, et al. Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Science 2002;297:1031-4.
-
(2002)
Science
, vol.297
, pp. 1031-1034
-
-
Okkenhaug, K.1
Bilancio, A.2
Farjot, G.3
-
10
-
-
42149091691
-
Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo
-
Ali K, Camps M, Pearce WP, et al. Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo. J Immunol 2008;180:2538-44.
-
(2008)
J Immunol
, vol.180
, pp. 2538-2544
-
-
Ali, K.1
Camps, M.2
Pearce, W.P.3
-
11
-
-
11144354388
-
Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue
-
Puri KD, Doggett TA, Douangpanya J, et al. Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue. Blood 2004;103:3448-56.
-
(2004)
Blood
, vol.103
, pp. 3448-3456
-
-
Puri, K.D.1
Doggett, T.A.2
Douangpanya, J.3
-
12
-
-
84861862873
-
The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice
-
Kang BN, Ha SG, Ge XN, et al. The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice. Am J Physiol Lung Cell Mol Physiol 2012;302:L1179-91.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L1179-L1191
-
-
Kang, B.N.1
Ha, S.G.2
Ge, X.N.3
-
13
-
-
65249151877
-
Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice
-
Marwick JA, Caramori G, Stevenson CS, et al. Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice. Am J Respir Crit Care Med 2009;179:542-8.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 542-548
-
-
Marwick, J.A.1
Caramori, G.2
Stevenson, C.S.3
-
14
-
-
51349091512
-
Phosphoinositide 3-kinase delta inhibitor as a novel therapeutic agent in asthma
-
Park SJ, Min KH, Lee YC. Phosphoinositide 3-kinase delta inhibitor as a novel therapeutic agent in asthma. Respirology 2008;13:764-71.
-
(2008)
Respirology
, vol.13
, pp. 764-771
-
-
Park, S.J.1
Min, K.H.2
Lee, Y.C.3
-
15
-
-
84875225940
-
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J Allergy Clin Immunol 2013;131:636-45.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 636-645
-
-
Barnes, P.J.1
-
16
-
-
0027639966
-
The modification and assembly of proteins in the endoplasmic reticulum
-
Gaut JR, Hendershot LM. The modification and assembly of proteins in the endoplasmic reticulum. Curr Opin Cell Biol 1993;5:589-95.
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 589-595
-
-
Gaut, J.R.1
Hendershot, L.M.2
-
17
-
-
47949099916
-
From endoplasmic-reticulum stress to the inflammatory response
-
Zhang K, Kaufman RJ. From endoplasmic-reticulum stress to the inflammatory response. Nature 2008;454:455-62.
-
(2008)
Nature
, vol.454
, pp. 455-462
-
-
Zhang, K.1
Kaufman, R.J.2
-
18
-
-
70549084746
-
Endoplasmic reticulum stress in disease: Mechanisms and therapeutic opportunities
-
Hosoi T, Ozawa K. Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities. Clin Sci (Lond) 2009;118:19-29.
-
(2009)
Clin Sci (Lond)
, vol.118
, pp. 19-29
-
-
Hosoi, T.1
Ozawa, K.2
-
19
-
-
85027927983
-
Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor êB activation
-
Kim SR, Kim DI, Kang MR, et al. Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor êB activation. J Allergy Clin Immunol 2013;132:1397-408.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 1397-1408
-
-
Kim, S.R.1
Kim, D.I.2
Kang, M.R.3
-
20
-
-
84860468095
-
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
-
Appenzeller-Herzog C, Hall MN. Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends Cell Biol 2012;22:274-82.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 274-282
-
-
Appenzeller-Herzog, C.1
Hall, M.N.2
-
21
-
-
77950537400
-
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response
-
Winnay JN, Boucher J, Mori MA, et al. A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response. Nat Med 2010;16:438-45.
-
(2010)
Nat Med
, vol.16
, pp. 438-445
-
-
Winnay, J.N.1
Boucher, J.2
Mori, M.A.3
-
22
-
-
0036314762
-
Eotaxin/CCL11 is involved in acute, but not chronic, allergic airway responses to Aspergillus fumigatus
-
Schuh JM, Blease K, Kunkel SL, et al. Eotaxin/CCL11 is involved in acute, but not chronic, allergic airway responses to Aspergillus fumigatus. Am J Physiol Lung Cell Mol Physiol 2002;283:L198-204.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
, pp. L198-L204
-
-
Schuh, J.M.1
Blease, K.2
Kunkel, S.L.3
-
23
-
-
55249088124
-
Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma
-
Ito K, Herbert C, Siegle JS, et al. Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma. Am J Respir Cell Mol Biol 2008;39:543-50.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 543-550
-
-
Ito, K.1
Herbert, C.2
Siegle, J.S.3
-
24
-
-
84860691114
-
The airway epithelium in asthma
-
Lambrecht BN, Hammad H. The airway epithelium in asthma. Nat Med 2012;18:684-92.
-
(2012)
Nat Med
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
25
-
-
77957102906
-
HIF-1α inhibition ameliorates an allergic airway disease via VEGF suppression in bronchial epithelium
-
Kim SR, Lee KS, Park HS, et al. HIF-1α inhibition ameliorates an allergic airway disease via VEGF suppression in bronchial epithelium. Eur J Immunol 2010;40:2858-69.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2858-2869
-
-
Kim, S.R.1
Lee, K.S.2
Park, H.S.3
-
27
-
-
79955617984
-
Mitochondrial dysfunction and oxidative stress in asthma: Implications for mitochondria-targeted antioxidant therapeutics
-
Reddy PH. Mitochondrial dysfunction and oxidative stress in asthma: implications for mitochondria-targeted antioxidant therapeutics. Pharmaceuticals (Basel) 2011;4:429-56.
-
(2011)
Pharmaceuticals (Basel)
, vol.4
, pp. 429-456
-
-
Reddy, P.H.1
-
28
-
-
84876906830
-
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species
-
Roca FJ, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell 2013;153:521-34.
-
(2013)
Cell
, vol.153
, pp. 521-534
-
-
Roca, F.J.1
Ramakrishnan, L.2
-
29
-
-
58349115630
-
Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study
-
Denning DW, O'Driscoll BR, Powell G, et al. Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. Am J Respir Crit Care Med 2009;179:11-18.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 11-18
-
-
Denning, D.W.1
O'Driscoll, B.R.2
Powell, G.3
-
31
-
-
72549115279
-
Expression of concern: Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity
-
Malhotra D, Thimmulappa R, Vij N, et al. Expression of concern: heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med 2009;180:1196-207.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 1196-1207
-
-
Malhotra, D.1
Thimmulappa, R.2
Vij, N.3
-
32
-
-
54049115076
-
Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
-
Korfei M, Ruppert C, Mahavadi P, et al. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008;178:838-46.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 838-846
-
-
Korfei, M.1
Ruppert, C.2
Mahavadi, P.3
-
33
-
-
84873110577
-
Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
-
Kim HJ, Jeong JS, Kim SR, et al. Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway. Sci Rep 2013;3:1142.
-
(2013)
Sci Rep
, vol.3
, pp. 1142
-
-
Kim, H.J.1
Jeong, J.S.2
Kim, S.R.3
-
34
-
-
57649233054
-
Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway
-
Balloy V, Sallenave JM, Wu Y, et al. Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. J Biol Chem 2008;283:30513-21.
-
(2008)
J Biol Chem
, vol.283
, pp. 30513-30521
-
-
Balloy, V.1
Sallenave, J.M.2
Wu, Y.3
-
35
-
-
79952750885
-
Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae
-
Boyle KB, Gyori D, Sindrilaru A, et al. Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae. J Immunol 2011;186:2978-89.
-
(2011)
J Immunol
, vol.186
, pp. 2978-2989
-
-
Boyle, K.B.1
Gyori, D.2
Sindrilaru, A.3
-
36
-
-
77249102130
-
Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis
-
Bonifazi P, D'Angelo C, Zagarella S, et al. Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis. Mucosal Immunol 2010;3:193-205.
-
(2010)
Mucosal Immunol
, vol.3
, pp. 193-205
-
-
Bonifazi, P.1
D'Angelo, C.2
Zagarella, S.3
-
37
-
-
33645827963
-
Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model
-
Lee KS, Lee HK, Hayflick JS, et al. Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB J 2006;20:455-65.
-
(2006)
FASEB J
, vol.20
, pp. 455-465
-
-
Lee, K.S.1
Lee, H.K.2
Hayflick, J.S.3
-
39
-
-
33746813191
-
Hydrogen peroxide induces vascular permeability via regulation of vascular endothelial growth factor
-
Lee KS, Kim SR, Park SJ, et al. Hydrogen peroxide induces vascular permeability via regulation of vascular endothelial growth factor. Am J Respir Cell Mol Biol 2006;35:190-7.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 190-197
-
-
Lee, K.S.1
Kim, S.R.2
Park, S.J.3
-
41
-
-
84881098989
-
Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology
-
Betz C, Stracka D, Prescianotto-Baschong C, et al. Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proc Natl Acad Sci USA 2013;110:12526-34.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12526-12534
-
-
Betz, C.1
Stracka, D.2
Prescianotto-Baschong, C.3
|