Gene therapy restores hair cell stereocilia morphology in inner ears of deaf whirler mice

Molecular Therapy

Volumn 24, Issue 1, 2016, Pages 17-25

  Chien, Wade W ^a,b   Isgrig, Kevin ^a   Roy, Soumen ^a   Belyantseva, Inna A ^a   Drummond, Meghan C ^a   May, Lindsey A ^a   Fitzgerald, Tracy S ^a   Friedman, Thomas B ^a   Cunningham, Lisa L ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRUCTURE; CELL SURVIVAL; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE THERAPY; HAIR CELL; HEARING; HEARING IMPAIRMENT; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INNER EAR; MOUSE; MOUSE MUTANT; NEWBORN; NONHUMAN; SCANNING ELECTRON MICROSCOPY; STEREOCILIUM; WHIRLER MICE; WILD TYPE; ADMINISTRATION AND DOSAGE; ANIMAL; CYTOLOGY; DEAFNESS; DEPENDOPARVOVIRUS; DISEASE MODEL; GENE VECTOR; GENETICS; HUMAN; INNER HAIR CELL; METABOLISM; PATHOLOGY; PROCEDURES; TREATMENT OUTCOME; ULTRASTRUCTURE;

MEMBRANE PROTEIN; WHRN PROTEIN, MOUSE;

ANIMALS; CELL SURVIVAL; DEAFNESS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; EAR, INNER; GENETIC THERAPY; GENETIC VECTORS; HAIR CELLS, AUDITORY, INNER; HUMANS; MEMBRANE PROTEINS; MICE; STEREOCILIA; TREATMENT OUTCOME;

EID: 84957841732     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.150     Document Type: Article

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