Cochlear gene transfer mediated by adeno-associated virus: Comparison of two surgical approaches

Laryngoscope

Volumn 125, Issue 11, 2015, Pages 2557-2564

  Chien, Wade W ^a,b   McDougald, Devin S ^a   Roy, Soumen ^a   Fitzgerald, Tracy S ^a   Cunningham, Lisa L ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adeno associated virus; cochleostomy; Gene therapy; hearing loss; round window

Indexed keywords

GREEN FLUORESCENT PROTEIN; MYOSIN VIIA; PARVOVIRUS VECTOR; LUMINESCENT AGENT;

ADENO ASSOCIATED VIRUS 2; ADENO ASSOCIATED VIRUS 8; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; COCHLEA; COCHLEA FENESTRA; COCHLEAR INFECTION; COCHLEOSTOMY; COMPARATIVE STUDY; CONTROLLED STUDY; EAR SURGERY; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE TRANSFER; HEARING IMPAIRMENT; INNER EAR DISEASE; INNER HAIR CELL; MOUSE; NONHUMAN; OUTER HAIR CELL; PRIORITY JOURNAL; SURGICAL APPROACH; VIRUS INFECTION; ANIMAL; CBA MOUSE; DEPENDOPARVOVIRUS; FEMALE; GENE THERAPY; GENETICS; HAIR CELL; MALE; METABOLISM; PARVOVIRUS INFECTION; PROCEDURES; SURGERY; VIROLOGY;

ANIMALS; COCHLEA; DEPENDOVIRUS; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GREEN FLUORESCENT PROTEINS; HAIR CELLS, AUDITORY, INNER; HEARING LOSS; LUMINESCENT AGENTS; MALE; MICE, INBRED CBA; OTOLOGIC SURGICAL PROCEDURES; PARVOVIRIDAE INFECTIONS; ROUND WINDOW, EAR;

EID: 84944513553     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.25317     Document Type: Article

References (22)

1. Morton NE,. Genetic epidemiology of hearing impairment. Ann N Y Acad Sci 1991; 630: 16-31.
2. Luebke AE, Foster PK, Muller CD, Peel AL,. Cochlear function and transgene expression in the guinea pig cochlea, using adenovirus- and adeno-associated virus-directed gene transfer. Hum Gene Ther 2001; 12: 773-781.
3. Luebke AE, Steiger JD, Hodges BL, Amalfitano A,. A modified adenovirus can transfect cochlear hair cells in vivo without compromising cochlear function. Gene Ther 2001; 8: 789-794.
4. Lalwani A, Walsh B, Reilly P, et al., A. Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus. Gene Ther 1998; 5: 277-281.
5. Shibata SB, Di Pasquale G, Cortez SR, Chiorini JA, Raphael Y,. Gene transfer using bovine adeno-associated virus in the guinea pig cochlea. Gene Ther 2009; 16: 990-997.
6. Di Pasquale G, Rzadzinska A, Schneider ME, Bossis I, Chiorini JA, Kachar B,. A novel bovine virus efficiently transduces inner ear neuroepithelial cells. Mol Ther 2005; 11: 849-855.
7. Stone IM, Lurie DI, Kelley MW, Poulsen DJ,. Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea. Mol Ther 2005; 11: 843-848.
8. Kilpatrick AM,. Globalization, land use, and the invasion of West Nile virus. Science 2011; 334: 323-327.
9. Iizuka T, Kanzaki S, Mochizuki H, et al., Noninvasive in vivo delivery of transgene via adeno-associated virus into supporting cells of the neonatal mouse cochlea. Hum Gene Ther 2008; 19: 384-390.
10. Xia L, Yin S, Wang J,. Inner ear gene transfection in neonatal mice using adeno-associated viral vector: a comparison of two approaches. PLoS One 2012; 7: e43218.
11. Konishi M, Kawamoto K, Izumikawa M, Kuriyama H, Yamashita T,. Gene transfer into guinea pig cochlea using adeno-associated virus vectors. J Gene Med 2008; 10: 610-618.
12. Bedrosian JC, Gratton MA, Brigande JV, Tang W, Landau J, Bennett J,. In vivo delivery of recombinant viruses to the fetal murine cochlea: transduction characteristics and long-term effects on auditory function. Mol Ther 2006; 14: 328-335.
13. Liu Y, Okada T, Sheykholeslami K, et al., Specific and efficient transduction of Cochlear inner hair cells with recombinant adeno-associated virus type 3 vector. Mol Ther 2005; 12: 725-733.
14. Li Duan M, Bordet T, Mezzina M, Kahn A, Ulfendahl M,. Adenoviral and adeno-associated viral vector mediated gene transfer in the guinea pig cochlea. Neuroreport 2002; 13: 1295-1299.
15. Akil O, Seal RP, Burke K, et al., Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy. Neuron 2012; 75: 283-293.
16. Jero J, Tseng CJ, Mhatre AN, Lalwani AK,. A surgical approach appropriate for targeted cochlear gene therapy in the mouse. Hear Res 2001; 151: 106-114.
17. Kilpatrick LA, Li Q, Yang J, Goddard JC, Fekete DM, Lang H,. Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear. Gene Ther 2011; 18: 569-578.
18. Lalwani AK, Walsh BJ, Reilly PG, Muzyczka N, Mhatre AN,. Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig. Gene Ther 1996; 3: 588-592.
19. Lalwani AK, Walsh BJ, Carvalho GJ, Muzyczka N, Mhatre AN,. Expression of adeno-associated virus integrated transgene within the mammalian vestibular organs. Am J Otol 1998; 19: 390-395.
20. House HP, Hansen MR, Al Dakhail AA, House JW,. Stapedectomy versus stapedotomy: comparison of results with long-term follow-up. Laryngoscope 2002; 112: 2046-2050.
21. Santa Maria PL, Domville-Lewis C, Sucher CM, Chester-Browne R, Atlas MD,. Hearing preservation surgery for cochlear implantation-hearing and quality of life after 2 years. Otol Neurotol 2013; 34: 526-531.
22. Thorne M, Salt AN, DeMott JE, Henson MM, Henson OW Jr, Gewalt SL,. Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images. Laryngoscope 1999; 109: 1661-1668.