The PDZ-domain protein whirlin facilitates mechanosensory signaling in mammalian proprioceptors

Journal of Neuroscience

Volumn 35, Issue 7, 2015, Pages 3073-3084

  de Nooij, Joriene C ^a   Simon, Christian M ^b   Simon, Anna ^g   Doobar, Staceyann ^a   Steel, Karen P ^h   Banks, Robert W ⁱ   Mentis, George Z ^b,c,d   Bewick, Guy S ^g   Jessell, Thomas M ^a,e,f  

^a Biochemistry and Molecular Biophysics   (United States)

^b Departments of Pathology and Cell Biology and Pharmacology   (United States)

^c Department of Neurokgy ^*  (United States)

^d Center for Motor Neuron Biology and Disease   (United States)

^e Kavli Institute for Brain Science   (United States)

^f Columbia University ^*  (United States)

^g UNIVERSITY OF ABERDEEN   (United Kingdom)

^h WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

ⁱ DURHAM UNIVERSITY   (United Kingdom)

Author keywords

Mechanoreception; Muscle spindle; PDZ proteins; Proprioceptors; Sensory motor control

Indexed keywords

PDZ PROTEIN; UNCLASSIFIED DRUG; WHIRLIN PROTEIN; EARLY GROWTH RESPONSE FACTOR 2; EGR2 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; PARVALBUMIN; PHOTOPROTEIN; TAU PROTEIN; WHEAT GERM AGGLUTININ; WHRN PROTEIN, MOUSE;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CONNECTOME; CONTROLLED STUDY; GENE EXPRESSION; HAIR CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING; MECHANORECEPTOR; MECHANOTRANSDUCTION; MOUSE; MUSCLE STRETCHING; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; PROPRIOCEPTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE CELL; SENSORY NERVE CONDUCTION; SIGNAL TRANSDUCTION; SOLEUS MUSCLE; SPIKE; SPINAL GANGLION; VESTIBULAR NERVE; ANIMAL; CELL CULTURE; COCHLEAR HAIR CELL; CYTOLOGY; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MUSCLE SPINDLE; PHYSIOLOGY; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ANIMALS; CELLS, CULTURED; EARLY GROWTH RESPONSE PROTEIN 2; GANGLIA, SPINAL; GENE EXPRESSION PROFILING; HAIR CELLS, AUDITORY; HOMEODOMAIN PROTEINS; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUSCLE SPINDLES; MUSCLE, SKELETAL; NEURAL CONDUCTION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARVALBUMINS; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; TAU PROTEINS; WHEAT GERM AGGLUTININS;

EID: 84923024254     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3699-14.2015     Document Type: Article

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